Abstract: A tissue clipping device includes (a) a first body extending from a proximal end to a distal end and including a first channel extending therethrough and (b) a plurality of first arm elements, each of the plurality of first arm elements extending radially into the first channel from a first end coupled to the first body to a second end proximal of its first end so that tissue drawn into a distal end of the first channel proximally beyond the second end of the plurality of first arm elements is compressed between each of the plurality of first arm elements and retained in the first channel.

Abstract: A medical/surgical device for performing tissue resection can include an endoscope with proximal and distal ends, defining working channels, and a snare assembly located in one of the working channels. The working channel may include a bend near the distal end and towards the outward radial wall of the endoscope. The snare assembly may include a snare loop and an actuation element imparted with the pre-formed angular bends and an actuation control handle. The bends of the actuation element and the working channel may be the same. The rotational manipulation of the actuation element may synchronize the pre-formed bend of the actuation element with the bend of the working channel to concentrically (or otherwise) align the deployed snare loop with the endoscope or endoscope attachments.

Abstract: Access and connection for a buried pipeline, wherein a hole is dug to a buried pipeline, a riser pipe is disposed within the hole, and one or more powered tools are lowered into the hole and activated such that work is performed on the pipeline without the need for anyone to be lowered into the hole. Because no one needs to be physically present down in the hole at the pipeline, the hole, and thus the surface disturbance can be much smaller than conventional pipeline work methods.

Abstract: According to an embodiment of the present disclosure, a medical device for deploying a ligation band may include a tubular body. The tubular body may include a proximal end, a distal end, a radially inner surface defining a lumen through the tubular body, and a radially outer surface. The radially outer surface may include protrusions arranged in rows extending at least partially around a proximal region of the radially outer surface. Protrusions in adjacent rows may be separated by a first distance. Surface features may extend at least partially around a distal region of the radially outer surface. Adjacent surface features may be separated by a second distance larger than the first distance.

Abstract: The medical device may include an elongate member having a proximal end and a distal end, and a plurality of legs coupled to the distal end of the elongate member. The medical device may also include a moveable element distal to the distal end of the elongate member, disposed around the plurality of legs. The moveable element may be reciprocally moveable relative to the elongate member and plurality of legs between a first and second position. The plurality of legs may be in a collapsed configuration when the moveable element is in the first position, and may be in an expanded configuration when the moveable element is in the second position.

Abstract: Provided herein is a method including the steps of: establishing at least one policy in a centralized policy management framework (PMF), wherein the policy includes at least one policy condition; monitoring data traffic; determining if the data traffic at least substantially meets one of the policy conditions; sending a trigger to the PMF, if at least one of the policy conditions is at least substantially met; generating an enforcement decision at the PMF, wherein the enforcement decision includes at least one enforcement action; sending the enforcement decision to an enforcement function; and enforcing the enforcement decision. A system for realizing this method is also provided.

Abstract: The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands of the double-stranded nucleic acid molecule are attached to a solid support at the 5? end, cleaving one or both strands of the double-stranded nucleic acid molecule, and subjecting the cleaved strand(s) to denaturing conditions to remove the portion of the cleaved strand(s) not attached to the solid support, thereby generating a partially or substantially single-stranded template for a nucleic acid sequencing reaction,

Abstract: Various aspects described or referenced herein are directed to different methods, systems, and computer program products relating to multi-media management and streaming techniques implemented over a computer network, including, for example, one or more features and/or functions relation to one or more of the following (or combinations thereof): venue-based streaming radio stations, mobile user graphical user interfaces, creation and streaming of dynamic streaming radio stations based on a user's geolocation, ticketing and reservations, etc.

Abstract: Provided are processes comprising crosslinking polyethylene or using crosslinked polyethylene. Furthermore, the processes may include compacting and/or sintering the polyethylene. The polyethylene can comprise virgin ultrahigh molecular weight polyethylene having a weight average molecular weight of at least 1,000,000 g/mol, to provide a compacted composition comprising virgin ultrahigh molecular weight polyethylene.

Abstract: Knee-walkers allow amputees and individuals with injuries to maintain independent movement. Their stability and steering is very important. The invention comprises a knee-walker (10) comprising a frame (20), at least two ground-engaging wheels (50) at the front, a seat (90), a steering column (70), and a steering belt (200) linking the steering column to the two front wheels, the two front wheels being steered by rotation of the steering column and consequent rotation of the belt.

Abstract: Various aspects described or referenced herein are directed to different methods, systems, and computer program products relating to multi-media management and streaming techniques implemented over a computer network. In one embodiment, a Multi-Media Management and Streaming (MMMS) System may be configured or designed to provide online users with “location based” streaming radio functionality. Users from different geographic locations may access a variety of MMMS System GUIs to access information relating to one or more artists/bands, songs, venues, and/or events such as live music performances. Users may also access a variety of MMMS System GUIs to search for, create, and/or share customized streaming radio stations which may be configured to identify, present information relating to, and/or play/stream music associated with one or more artists/bands, songs, venues, and/or events.

Abstract: The invention relates to modified polymerase enzymes which exhibit improved incorporation of nucleotide analogs bearing substituents at the 3? position of the sugar moiety that are larger in size than the naturally occurring 3? hydroxyl group. Also described are methods of using the polymerases to incorporate nucleotides into polynucleotides, particularly in the context of DNA sequencing.

Abstract: The present invention provides methods for creating an array of features on a surface based on content transferred from a plurality of beads to the surface. Nucleic acid content can be transferred using a method including the steps of (a) providing a surface having one or more primer oligonucleotides attached to the surface; (b) providing a pool of beads, wherein beads in the pool have a plurality of templates attached thereto, the plurality comprising multiple copies of a single nucleic acid template sequence; (c) arraying the beads onto the surface by hybridizing the templates to the primer oligonucleotides; and (d) extending the primers to produce copies of the templates attached to the surface.

Abstract: A petrophysically regularized time domain nuclear magnetic resonance (NMR) inversion includes using an NMR tool to acquire NMR data and inverting the acquired NMR data in a time domain using petrophysical constraints. The inverted NMR data is analyzed. The petrophysical constraints may be identified by: determining a number of porobodons to seek, defining a plurality of zones in which only a subset of porobodon sets is present, and stacking all NMR echoes in each zone satisfying discriminators. The number of porobodons to seek may be based on knowledge of core samples, logs, and NMR sensitivity. The discriminator logs may be logs sensitive to porosity partitioning. A computing system having a processor, a memory, and a program stored in memory may be configured to perform the method. The system may be conveyed downhole on a wireline, a while-drilling drill string, a coiled tubing, a slickline, or a wired drill pipe.

Abstract: Modified DNA polymerases have an affinity for DNA such that the polymerase has an ability to incorporate one or more nucleotides into a plurality of separate DNA templates in each reaction cycle. The polymerases are capable of forming an increased number of productive polymerase-DNA complexes in each reaction cycle. The modified polymerases may be used in a number of DNA sequencing applications, especially in the context of clustered arrays.

Abstract: A medical device may include a housing. The housing may include an outer wall, an inner wall spaced from the outer wall, and a cavity defined by the outer wall and the inner wall. The distal end of the outer wall may be disposed proximally from the distal end of the inner wall. The housing may further define a passageway therethrough. The cavity may be in fluid communication with a port configured to adjust pressure within the cavity.

Abstract: A medical device for resecting tissue. The medical device is slidably disposed within a working channel of an elongate introduction sheath. The medical device includes an elongate shaft having a proximal end, a distal end, and a lumen extending therebetween. The distal end of the elongate shaft may include an opening in communication with the lumen. In addition, the medical device includes a support structure having a slot extending along an inner surface of the support structure in communication with the lumen of the elongate shaft. The medical device further includes a snare loop having a first position disposed within the slot of the support structure, and a second position disposed within the lumen of the elongate shaft. An actuation member is slidably disposed within the lumen of the elongate shaft and is connected to the snare loop.

Abstract: Medical devices having one or more micropatterned surfaces (e.g., micropatterned coatings).

Abstract: A device for tissue resection and methods of using the same is disclosed, including a snare loop and a tubular handle. The snare loop has both conductive and insulated portions such that the snare loop can be used to cut tissue selectively to make perimeter cuts on the tissue to be resected. The snare loop may be placed and tightened on a target tissue and may be activated for cutting the tissue to be resected by passing an electrical current through the snare loop. Some embodiments of the device include a hood and cutting wire for making perimeter cuts on the tissue to be resected.

Abstract: A method for reducing mucus accumulation in an airway including disposing an implantable device within an airway, wherein the implantable device has a first end, a second end, and an inner surface defining a lumen extending from the first end to the second end; wherein at least a portion of the inner surface has a hydrophobic polymer coating thereon, wherein a polymer coating surface has dynamic water contact angles of 145 degrees or greater; and wherein the implantable device is constructed and arranged to maintain patency of the airway; wherein accumulation of mucus is reduced as compared to a similar implantable device without the hydrophobic portion of the inner surface. An implantable medical device having a superhydrophobic surface and a method of making an implantable medical device having a superhydrophobic surface are also provided.