Abstract: The present invention relates to antibodies capable of binding a human V?9V?d2 T cell receptor. The invention further relates to pharmaceutical compositions comprising the antibodies of the invention and to uses of the antibodies of the invention for medical treatment.

Abstract: A method for on-demand access to table partitions may include receiving, at a data execution engine, a query accessing a database table divided into a first partition and a second partition stored at different nodes of the database. The data execution engine may respond to the query by acquiring a lock on the database table and instantiating data structures to support the execution of the query without loading any of the partitions of the database table into a main memory. Instead, the loading of the individual partitions of the database table may be delegated to the operators tasked with performing the operations included in the execution plan for the query. Each operator may refrain from loading those partitions of the database table that are determined to be unnecessary for performing the individual operations. Related systems and computer program products are also provided.

Abstract: A method for allocating worker threads may include receiving a first fetch call for a query accessing a dataset stored at a database. The first fetch call may require a first portion of a result for the query. A first quantity of worker threads may be allocated to generate the first portion of the result for the query in response to the first fetch call. In response to a second fetch call for the query by determining a threshold corresponding to the first quantity of worker threads, a second quantity of data required for the second fetch call, and a third quantity of data buffered from the first fetch call. A second quantity of worker threads to generate a second portion of the result for the query may be allocated based on the threshold. Related systems and computer program products are also provided.

Abstract: Provided herein are antibodies capable of binding human PSMA and capable of binding a human V?9V?2 T cell receptor. In particular, provided herein are pharmaceutical compositions comprising the antibodies capable of binding human PSMA and capable of binding a human V?9V? T cell receptor and uses of the antibodies for medical treatment.

Abstract: Aspects of the current subject matter are directed to providing query results to clients by incorporating pause and/or detach operations into the query execution after a first fetch of results. The pause and the detach operations for query execution consistent with implementations of the current subject matter result in reduced times and conserved resources in providing query results by computing only results necessary to satisfy a first fetch call prior to computing results necessary to satisfy subsequent fetch calls.

Abstract: The invention relates to a method for providing a composition selected from the group consisting of aqueous pastes, inks, paints and coating formulations with retroreflective properties, said method comprising the steps of: a) providing an aqueous paste, ink, paint or coating formulation without retroreflective properties, said aqueous paste, ink, paint or coating formulation having a viscosity ?1 of between 0.25 and 1000 Pa·s at a shear rate of 0.01 s-1; b) providing an aqueous pseudoplastic gel composition comprising a thickener; c) admixing the aqueous ink, paint or coating formulation provided in step (a) with the aqueous pseudoplastic gel composition provided in step (b) in a weight ratio of between 30 : 70 to 70 : 30; and d) admixing the mixture obtained in step (c) with 0 - 2 wt.%, based on the total weight of the aqueous paste, ink, paint or coating formulation with retroreflective properties, of a thickener.

Abstract: Aspects of the current subject matter are directed to providing query results to clients by incorporating pause and/or detach operations into the query execution after a first fetch of results. The pause and the detach operations for query execution consistent with implementations of the current subject matter result in reduced times and conserved resources in providing query results by computing only results necessary to satisfy a first fetch call prior to computing results necessary to satisfy subsequent fetch calls.

Abstract: A method may include responding to a query to retrieve data from a database by identifying a plurality of query execution plans. An overall robustness value may be determined for each query execution plan. The overall robustness value of a query execution plan may correspond to a sum of individual robustness values for each operator included in the query execution plan. Each operator may have an individual robustness value that corresponds to a first change in a total cost of a query execution plan including the operator relative to a second change in an output cardinality of the operator. One of the plurality of query execution plans may be selected based on the overall robustness value of each of the plurality of query execution plans. The query may be executed by performing a sequence of operators included in the selected one of the plurality of query execution plan.

Abstract: The invention relates to methods for the treatment of cancer. In particular, the invention relates to methods for the treatment of cancer, comprising administration of a high dose of an antibody capable of binding a human V?9V?2 T cell receptor.

Abstract: Aspects of the current subject matter are directed to executing queries on tables in which one or more columns contain a single value. Upon execution of a query, columns in which a single value is contained are identified, and a pre-compiled code entry containing relevant identifying information is compiled as part of a query execution plan. The query execution plan is used for subsequent query executions, alleviating the need to access the columns during the subsequent query executions that involve the columns. A fingerprint value may be used to track if changes to relevant tables occur.

Abstract: In some aspects, there is provided a method that may include: intercepting a query requiring access to data stored in a table. The query may include an identifier, which may be associated with a row of the table and a reference to a column of the table. The method may further include preparing a table object to enable access to the data stored in the row and the column of the table. The preparing may include locating the row associated with the identifier. The preparing may further include acquiring locks for the data stored in the located row and the column in the row. The method may also include executing the query upon preparing the table object. Related systems, methods, and articles of manufacture are also described.

Abstract: A method, a system, and a computer program product for generating a query executable plan. A query requiring access to data stored in a database system is received. Based on the received query, a query execution plan having a plurality of query execution pipelines is generated. Each query execution pipeline in the plurality of query execution pipelines is configured to execute a plurality of operations in a predetermined order associated with each query execution pipeline. The generated query execution plan is fragmented into a plurality of fragments. Each fragment has one or more query execution pipelines in the plurality of query execution pipelines. The received query is executed by executing each fragment in the plurality of fragments.

Abstract: The present disclosure relates to the use of 2-iminobiotin for treating brain cell injury, in particular in adults. The treatment may be used for the treatment of cerebral hypoxia-ischemia and/or reperfusion injury, including one or more symptoms thereof. Provided are methods of treatment comprising administering a therapeutically effective dose of 2-iminobiotin to an individual in need thereof.

Abstract: A query is received at a database execution engine. The query is executed by the database execution engine, the executing including executing one or more threads that operate on versions of data of the delta fragment; acquiring and releasing, by a first thread, a latch on a first version of the data of the delta fragment, the releasing is performed prior to the first thread entering a wait state; and reclaiming the first version of the data of the delta fragment from memory and during execution of the query. Related systems, methods, and articles of manufacture are also described.

Abstract: A method, a system, and a computer program product for executing a query in a database system. A query plan for execution of a query is generated. The query requires access to at least one table stored in a database system. One or more occurrences of one or more duplicate predicates is detected in the query plan. In response to detecting a first occurrence of the duplicate predicates, one or more intermediate query execution results responsive to the duplicate predicates are generated. The generated intermediate query execution results are cached. Query execution results incorporating cached intermediate query execution results being responsive to each occurrence of the duplicate predicates subsequent to the first occurrence of the duplicate predicates in the query plan are generated.

Abstract: The present invention relates to the field of immunology, more in particular to the field of binding moieties and/or immunoglobulins which bind to human CD1d, including antibodies and fragments thereof that modify CD1d-mediated biological functions such as enhanced activation and reduced activation of CD1d-restricted T cells, including the natural killer T-cells and gamma-delta T-cells, and modulation of the function of cells expressing CD1d. The invention also relates to bi-, tri- or multi-specific immunoglobulins that bind to CD1d and a gamma-delta TCR and/or a tumor target. The invention further relates to pharmaceutical preparations and use of such mono-, bi-, and tri- or multi-specific binding moieties and/or immunoglobulins in the treatment of diseases or disorders.

Abstract: The invention relates to a process for preparing PCL-comprising microparticles, to microparticles obtainable by said process, to gel hence obtained and to several uses of the gel such as for the preparation of a medicament for treating a skin abnormality or disfigurement, and/or for controlling bladder function and/or controlling gastric reflux and/or for treating erectile dysfunction and/or for treating vocal cords. The gel may also be used for cosmetic applications.

Abstract: A physio-logical migration of a database from a source system to a target system may include exporting a catalog of the database in a data interchange format that preserves the hierarchical dependencies present amongst the entities included in the catalog. The physio-logical migration of the database may further include exporting the contents of a table in the database in a binary format compatible at the target system. The binary format may be a data buffer having a metadata portion, a fixed-size portion, and a page chain portion. Where the target system is a cloud-based system, the physio-logical migration of the database may include exporting the catalog and the contents of the table to a cloud-based object store before importing the catalog and the contents of the table to the target system. Related systems and articles of manufacture, including computer program products, are also provided.

Abstract: A method may include responding to a query to retrieve data from a database by identifying a plurality of query execution plans. An overall robustness value may be determined for each query execution plan. The overall robustness value of a query execution plan may correspond to a sum of individual robustness values for each operator included in the query execution plan. Each operator may have an individual robustness value that corresponds to a first change in a total cost of a query execution plan including the operator relative to a second change in an output cardinality of the operator. One of the plurality of query execution plans may be selected based on the overall robustness value of each of the plurality of query execution plans. The query may be executed by performing a sequence of operators included in the selected one of the plurality of query execution plan.

Abstract: A method may include responding to a query to retrieve data from a database by identifying a plurality of query execution plans. An overall robustness value may be determined for each query execution plan. The overall robustness value of a query execution plan may correspond to a sum of individual robustness values for each operator included in the query execution plan. Each operator may have an individual robustness value that corresponds to a first change in a total cost of a query execution plan including the operator relative to a second change in an output cardinality of the operator. One of the plurality of query execution plans may be selected based on the overall robustness value of each of the plurality of query execution plans. The query may be executed by performing a sequence of operators included in the selected one of the plurality of query execution plan.