Patents by Inventor Paul A. Wyman

Paul A. Wyman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10301121
    Abstract: In one embodiment, a system has a carousel that has a guiderail that forms a loop that has a loading position and an unloading position. The carousel also has a plurality of buckets, each having an upper end and a lower end. The lower end includes at least one bottom wall that is moveable between (i) a transporting configuration where the at least one bottom wall substantially closes the lower end of the bucket and (ii) a discharge configuration where the at least one bottom wall is moved so as to define an opening in the lower end of the bucket. The buckets are supported by the guiderail such that the buckets can be driven from the loading position towards the unloading position in the transporting configuration. The buckets can be transitioned to the discharge configuration so as to unload inventory items at the unloading position into a packaging material.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: May 28, 2019
    Assignee: Amazon Technologies, Inc.
    Inventors: Brian Hoffman, Martin Peter Aalund, David Alspaugh, Samuel Gardner Garrett, Paul Roy Raines, Jr., Timothy Alan Talda, Akshay Tilekar, Stephanie Tomasetta, Eric Wyman, Toby Ge Xu
  • Patent number: 10296870
    Abstract: A packaging system employs a cartridge having moveable walls such that the cartridge discharges or inducts one or more items into a cavity of a package, such as a film that is sealed into a pouch or mailer. A bottom wall of the cartridge is retracted relative to an end panel of the cartridge during the induction process.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: May 21, 2019
    Assignee: Amazon Technologies, Inc.
    Inventors: Brian Hoffman, Martin Peter Aalund, David Alspaugh, Samuel Gardner Garrett, Paul Roy Raines, Jr., Timothy Alan Talda, Akshay Tilekar, Stephanie Tomasetta, Eric Wyman, Toby Ge Xu
  • Publication number: 20160075841
    Abstract: A method for activating silicone rubber surfaces comprising steps of: i) swelling at least the surface of the silicone rubber matrix with a silicone rubber swelling solvent; ii) treating the silicone rubber matrix during or after the swelling with a solution comprising at least a reactive silane, the reactive silane comprising: a) at least one Si—C bond and; b) at least one hydrolytically labile bond linked to at least one of the Si atoms present in the reactive silane and; c) at least one functional group F1 connected via a Si—C bond to the same or an other Si atom present in the reactive silane, the functional group comprising electrophilic and/or nucleophilic moieties, and/or at least one functional group F2 connected via a Si—C bond to the same or an other Si atom present in the reactive silane comprising moieties which become electrophilic or nucleophilic moieties by a mechanism selected from the group consisting of ring opening of a cyclic structure, hydrolysis, displacement or by a migration reactio
    Type: Application
    Filed: November 23, 2015
    Publication date: March 17, 2016
    Inventors: John Andrew ZUPANCICH, Paul WYMAN
  • Patent number: 9221999
    Abstract: A method for activating silicone rubber surfaces comprising steps of: i) swelling at least the surface of the silicone rubber matrix with a silicone rubber swelling solvent; ii) treating the silicone rubber matrix during or after the swelling with a solution comprising at least a reactive silane, the reactive silane comprising: a) at least one Si—C bond and; b) at least one hydrolytically labile bond linked to at least one of the Si atoms present in the reactive silane and; c) at least one functional group F1 connected via a Si—C bond to the same or an other Si atom present in the reactive silane, the functional group comprising electrophilic and/or nucleophilic moieties, and/or at least one functional group F2 connected via a Si—C bond to the same or an other Si atom present in the reactive silane comprising moieties which become electrophilic or nucleophilic moieties by a mechanism selected from the group consisting of ring opening of a cyclic structure, hydrolysis, displacement or by a migration reaction;
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: December 29, 2015
    Assignee: DSM IP ASSETS B.V.
    Inventors: John Andrew Zupancich, Paul Wyman
  • Patent number: 8795830
    Abstract: Disclosed is a method to provide a metal wire with a coating system comprising a primer and a topcoat, particularly a hydrophilic, lubricious topcoat. The method comprises applying directly onto the wire metal a primer coating composition, which is an aqueous coating composition comprising a multiphase vinyl polymer, the polymer comprising a first phase having a Tg in the range of from ?20° C. to 40° C. and a hard phase having a Tg in the range of from 25° C. to 120° C. The primer has good adhesion to both the metal surface and the topcoat, and provides the eventual coating system with, inter alia, a good flexibility.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: August 5, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Paul Wyman, de Nik Bont, Hinrike Malda, Mamix Rooijmans, Jurgen Scheerder, Rajasingham Satgurunathan, Thomas L. M. Frijns
  • Publication number: 20120322954
    Abstract: A method for activating silicone rubber surfaces comprising steps of: i) swelling at least the surface of the silicone rubber matrix with a silicone rubber swelling solvent; ii) treating the silicone rubber matrix during or after the swelling with a solution comprising at least a reactive silane, the reactive silane comprising: a) at least one Si—C bond and; b) at least one hydrolytically labile bond linked to at least one of the Si atoms present in the reactive silane and; c) at least one functional group F1 connected via a Si—C bond to the same or an other Si atom present in the reactive silane, the functional group comprising electrophilic and/or nucleophilic moieties, and/or at least one functional group F2 connected via a Si—C bond to the same or an other Si atom present in the reactive silane comprising moieties which become electrophilic or nucleophilic moieties by a mechanism selected from the group consisting of ring opening of a cyclic structure, hydrolysis, displacement or by a migration reaction;
    Type: Application
    Filed: December 23, 2010
    Publication date: December 20, 2012
    Inventors: John Andrew Zupancich, Paul Wyman
  • Publication number: 20120041545
    Abstract: Disclosed is a method to provide a metal wire with a coating system comprising a primer and a topcoat, particularly a hydrophilic, lubricious topcoat. The method comprises applying directly onto the wire metal a primer coating composition, which is an aqueous coating composition comprising a multiphase vinyl polymer, the polymer comprising a first phase having a Tg in the range of from ?20° C. to 40° C. and a hard phase having a Tg in the range of from 25° C. to 120° C. The primer has good adhesion to both the metal surface and the topcoat, and provides the eventual coating system with, inter alia, a good flexibility.
    Type: Application
    Filed: January 11, 2010
    Publication date: February 16, 2012
    Inventors: Paul Wyman, de Nik Bont, Hinrike Malda, Mamix Rooijmans, Jurgen Scheerder, Rajasingham Satgurunathan, ThomasL L.M. Frijns
  • Publication number: 20070142431
    Abstract: The invention relates to novel quinoline derivatives, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments particularly in treating disorders of the central nervous system (CNS).
    Type: Application
    Filed: August 5, 2004
    Publication date: June 21, 2007
    Inventors: Wai Chan, Paul Smith, Paul Wyman
  • Patent number: 6411451
    Abstract: The present invention pretains to a device for protecting the human eye by means of a narrow bandwith interference filter which filters out one or more specific wavelengths of light emitted in the form of a coherent, concentrated beam that is laser radiation and in coherent light, an image intensifier for amplifying an image passing through the narrow bandwidth filter to an observable light level, and a neutral density filter which reduces image reflected illuminance to avoid detection.
    Type: Grant
    Filed: March 28, 1990
    Date of Patent: June 25, 2002
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Gerald Fliss, Robert E. Lee, George P. Mueller, Tim D. Andreadis, Paul Wyman
  • Patent number: 6094136
    Abstract: A home burglar alarm system, dependent on a telephone line for operability, can be protected by covering the exterior telephone wiring with an enclosure fastened to the building exterior surface. The enclosure conceals and physically shields the telephone wiring form attack by a would-be intruder. As back-up protection, the wiring enclosure is provided with an audible alarm system that is triggered by breakage or destruction of the enclosure.
    Type: Grant
    Filed: January 26, 1999
    Date of Patent: July 25, 2000
    Inventor: Paul Wyman
  • Patent number: 5580885
    Abstract: The use of a compound of formula (I) or pharmaceutically acceptable salt thereof, in which X.sub.1 --(CH.sub.2).sub.x --X.sub.2 forms a 5-7 membered ring wherein: X.sub.1 is O or S; X.sub.2 is O, S, NR or NRCO wherein R is hydrogen or C.sub.1-6 alkyl; x is 1, 2 or 3; Y is O or NH; Z is sub-formula (a), (b) or (c) in the manufacture of a medicament for use in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders.
    Type: Grant
    Filed: July 28, 1994
    Date of Patent: December 3, 1996
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Francis D. King, Laramie M. Gaster, Keith R. Mulholland, Shirley K. Rahman, Paul A. Wyman, Gareth J. Sanger, Kay A. Wardle, Gordon S. Baxter, Guy A. Kennett, Alberto J. Kauman
  • Patent number: 5552398
    Abstract: Compounds of formula (I), ##STR1## wherein L is N or CR.sub.c, wherein R.sub.c is hydrogen, alkoxy, halo, alkyl or cyano; Q is NR.sub.1, CH.sub.2, O, or S; R.sub.a is hydrogen, halo, alkyl, amino, nitro or alkoxy; R.sub.b is hydrogen, halo, alkyl or alkoxy; R.sub.1 is hydrogen, alkyl, alkenyl, aralkyl, alkanoyl, or alkanoylalkyl; R.sub.2 is alkoxy; R.sub.3 is hydrogen, chloro or fluoro; R.sub.4 is hydrogen, alkyl, amino optionally substituted by alkyl, halo, hydroxy or alkoxy; R.sub.5 is hydrogen, halo, alkyl, alkoxy, nitro, amino or alkylthio; R.sub.6 is hydrogen, halo, alkyl, alkoxy or amino; n is 0, 1, 2, 3, or 4; p and m are independently 0, 1 or 2; and R.sub.q is hydrogen or C.sub.1-6 are 5-HT.sub.4 receptor antagonists.
    Type: Grant
    Filed: November 14, 1994
    Date of Patent: September 3, 1996
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Francis D. King, Laramie M. Gaster, Paul A. Wyman
  • Patent number: 5541194
    Abstract: Novel compounds of formula (I), processes for their preparation, and their use as pharmaceutical agents are described: ##STR1## in which p represents an integer of 2 to 4; r represents an integer of 1 or 2; s represents 0 or 1; and X represents a group ##STR2## in which A.sub.1 is oxygen or sulphur, one of A.sub.2 and A.sub.3 is CR.sub.1 and the other is nitrogen or CR.sub.2, or A.sub.2 is oxygen or sulphur, A.sub.1 is CH and A.sub.3 is CR.sub.1, where R.sub.1 and R.sub.2 are independently selected from hydrogen and C.sub.1-2 alkyl, with the proviso that when r is 2, R.sub.1 and R.sub.2 are hydrogen or methyl. The novel compounds of this invention may be used to treat or to prevent dementia in mammals.
    Type: Grant
    Filed: January 6, 1995
    Date of Patent: July 30, 1996
    Assignee: Beecham Group p.l.c.
    Inventors: Barry S. Orlek, Paul A. Wyman, Harry J. Wadsworth
  • Patent number: 5492919
    Abstract: The invention provides the use of a compound of formula (I) ##STR1## wherein A, E, F, U, X, Y, Z, are as defined in the specification, or a pharmaceutically acceptable salt thereof, for the treatment of diarrhea predominant irritable bowel syndrome.
    Type: Grant
    Filed: July 6, 1994
    Date of Patent: February 20, 1996
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Gareth J. Sanger, Francis D. King, Gordon S. Baxter, Laramie M. Gaster, Alberto J. Kaumann, Guy A. Kennett, Keith R. Mulholland, Mythily Vimal, Kay A. Wardle, Paul A. Wyman, Rodney C. Young
  • Patent number: 5470859
    Abstract: A pharmaceutical composition useful to treating dementia which comprises a compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which p is 1 and either m is 0 and n is 2 or 3 or m is 1 and n is 2, or p is 2, m is 0 and n is 2, and Z is a heterocyclic group ##STR2## in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, or three nitrogen atoms, any amino nitrogen being substituted by a C.sub.1-2 alkyl, cyclopropyl or propargyl group, and any ring carbon atom being optionally substituted by a group R.sub.1 ; or a group ##STR3## which A.sub.1, A.sub.2 and A.sub.3 complete a 5-membered aromatic ring and A.sub.1 is oxygen or sulphur, one of A.sub.2 and A.sub.3 is CR.sub.2 and the other is nitrogen or CR.sub.3, or A.sub.2 is oxygen or sulphur, one of A.sub.1 and A.sub.3 is CR.sub.2 and the other is CR.sub.3 ; and R.sub.1, R.sub.2 and R.sub.
    Type: Grant
    Filed: August 2, 1990
    Date of Patent: November 28, 1995
    Assignee: Beecham Group p.l.c.
    Inventors: Harry J. Wadsworth, Paul A. Wyman, Steven Dabbs, Sarah M. Jenkins
  • Patent number: 5157160
    Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which Z is a heterocyclic group ##STR2## in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, or three nitrogen atoms, any amino nitrogen being substituted by a C.sub.1-2 alkyl, cyclopropyl or propargyl group, and any ring carbon atom being optionally substituted by a group R.sub.1 ; or a group ##STR3## in which A.sub.1, A.sub.2 and A.sub.3 complete a 5-membered aromatic ring and A.sub.1 is oxygen or sulphur, one of A.sub.2 and A.sub.3 is CR.sub.2 and the other is nitrogen or CR.sub.3, or A.sub.2 is oxygen or sulphur, one of A.sub.1 and A.sub.3 is CR.sub.2 and the other is CR.sub.3 ; and R.sub.1, R.sub.2 and R.sub.3 are independently selected from hydrogen, halogen, CN, OR.sub.4, SR.sub.4, N(R.sub.4).sub.2, NHCOR.sub.4, NHCOOCH.sub.3, NHCOOC.sub.2 H.sub.5, NHOR.sub.4, NHNH.sub.2, NO.sub.2, COR.sub.4, COR.sub.
    Type: Grant
    Filed: June 17, 1991
    Date of Patent: October 20, 1992
    Assignee: Beecham Group p.l.c.
    Inventor: Paul A. Wyman
  • Patent number: 5132316
    Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which X represents R.sub.1 OOC-- in which R.sub.1 is C.sub.1-4 alkyl, C.sub.2-4 alkenyl or C.sub.2-4 alkynyl; R.sub.2 O-- in which R.sub.2 is C.sub.1-2 alkyl, C.sub.1 -2 alkylcarbonyl or aminocarbonyl optionally substituted by one or two methyl groups;a group ##STR2## in which Y represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, any amino nitrogen optionally substituted by a C.sub.1-2 alkyl group, Y being optionally C-substituted by a methyl group; ora group ##STR3## in which A.sub.1 is oxygen or sulphur, one of A.sub.2 and A.sub.3 is CR.sub.3 and the other is nitrogen or CR.sub.4 where R.sub.3 and R.sub.4 are independently selected from hydrogen and methyl; and each of p and q independently represents an integer of 2 to 4.
    Type: Grant
    Filed: September 21, 1990
    Date of Patent: July 21, 1992
    Assignee: Beecham Group p.l.c.
    Inventors: Michael S. Hadley, Paul A. Wyman, Barry S. Orlek
  • Patent number: 5091397
    Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which one of X and Y represents hydrogen and the other represents --CH.sub.2 --Z where Z is a group ##STR2## in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, or three nitrogen atoms, any amino nitrogen being optionally substituted by a C.sub.1-2 alkyl, cyclopropyl or propargyl group, and any ring carbon atom being optionally substituted by a group R.sub.1 ; or a group ##STR3## in which A.sub.1, A.sub.2 and A.sub.3 complete a 5-membered aromtic ring and A.sub.1 is oxygen or sulphur, one of A.sub.2 and A.sub.3 is CR.sub.2 and the other is nitrogen or CR.sub.3, or A.sub.2 is oxygen or sulphur, one of A.sub.1 and A.sub.3 is CR.sub.2 and the other is CR.sub.3 ; and R.sub.1, R.sub.2 and R.sub.3 are independently selected from hydrogen, halogen, CN, OR.sub.4, SR.sub.4, N(R.sub.4).sub.2, NHCOR.sub.4, NHCOOCH.sub.
    Type: Grant
    Filed: September 29, 1989
    Date of Patent: February 25, 1992
    Assignee: Beecham Group p.l.c.
    Inventors: Harry J. Wadsworth, Michael S. Hadley, Paul A. Wyman, Sarah M. Jenkins
  • Patent number: 5043342
    Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1##
    Type: Grant
    Filed: December 21, 1989
    Date of Patent: August 27, 1991
    Assignee: Beecham Group p.l.c.
    Inventors: Michael S. Hadley, Paul A. Wyman, Barry S. Orlek
  • Patent number: 5043343
    Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which Z is a heterocyclic group ##STR2## in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, or three nitrogen atoms, any amino nitrogen being substituted by a C.sub.1-2 alkyl, cyclopropyl or propargyl group, and any ring carbon atom being optionally substituted by a group R.sub.1 ; or a group ##STR3## in which A.sub.1, A.sub.2 and A.sub.3 complete a 5-membered aromatic ring and A.sub.1 is oxygen or sulphur, one of A.sub.2 and A.sub.3 is CR.sub.2 and the other is nitrogen or CR.sub.3, or A.sub.2 is oxygen or sulphur, one of A.sub.1 and A.sub.3 is CR.sub.2 and the other is CR.sub.3 ; and R.sub.1, R.sub.2 and R.sub.3 are independently selected from hydrogen, halogen, CN, OR.sub.4, SR.sub.4, N(R.sub.4).sub.2, NHCOR.sub.4, NHCOOCH.sub.3, NHCOOC.sub.2 H.sub.5, NHOR.sub.4, NHNH.sub.2, NO.sub.2, COR.sub.4, COR.sub.
    Type: Grant
    Filed: August 14, 1990
    Date of Patent: August 27, 1991
    Assignee: Beecham Group p.l.c.
    Inventor: Paul A. Wyman