Abstract: A system and method to create a robust topology of a layout of cores for performing a function on an array of cores arranged in a grid is disclosed. A defective core file of location of defective cores in the array and an optimal ideal topology of a configuration layout of at least some of the cores is input. The location of at least one defective core of the array is determined. At least some of the cores in the array of cores are assigned to the optimal initial topography of cores in the array. It is determined whether at least one defective core is in the optimal initial topography. The functions of the cores in the row and the column of the at least one defective core are assigned to additional neighboring cores in the array of cores to create the robust topology.

Abstract: L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates for treatment, amelioration and/or prevention of protein aggregation/tangles/plaques and diseases associated with protein aggregation/tangles/plaques. In particular, treatments and uses for L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates include Alzheimer's disease (AD), Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Huntington disease (HD).

Abstract: Paper towel rolls that exhibit novel combinations of physical properties, such as Basis Weight, Roll Density, and Roll Diameter, such that the paper towel rolls meet consumers' needs, and method for making such novel paper towel rolls and marketing such novel paper towel rolls are provided.

Abstract: The present invention relates to compounds that are useful as radiopharmaceuticals and radioimaging agents which bear a radionuclide-chelating agent. These coordinated compounds are useful in radiotherapy and diagnostic imaging. The invention also relates to methods of diagnosis, prognosis and therapy utilising the non-coordinated and radiolabelled compounds of the invention.

Abstract: Cable routing approaches are described that allow cables to pass through a traditional chain joint without reducing the strength capacity or impairing the range of motion of the joint. The cable routing approaches permit the cables to be housed inside the structure of the robotic arm and pass through the chain joint in a manner that does not limit the width of the chain.

Abstract: Embodiments herein relate to ear-wearable devices and systems with features to track orthopedic issues and orthopedic procedure recovery. In an embodiment, an ear-wearable device is included having a control circuit, a microphone, and a sensor package. The ear-wearable device can be configured to receive an input regarding an occurrence of an orthopedic procedure, evaluate signals from the sensor package and/or the microphone, and determine a rehabilitative status of a device wearer with respect to the orthopedic procedure. Other embodiments are also included herein.

Abstract: Paper towel rolls that exhibit novel combinations of physical properties, such as Basis Weight, Roll Density, and Roll Diameter, such that the paper towel rolls meet consumers' needs, and method for making such novel paper towel rolls and marketing such novel paper towel rolls are provided.

Abstract: A hydraulic pump or motor includes a mounting flange that is disposed at the first end of the housing. The mounting flange defines a pair of bolt receiving slots that are disposed along the X-axis on either side of the shaft. The pair of bolt receiving slots each define a radius center that are spaced away from each other a X dimension, and a pilot projection extends longitudinally away from the mounting flange, defining a pilot projection diameter. A ratio of the X dimension to the pilot projection diameter ranges from 1.1 to 1.5.

Abstract: The present invention is directed to sarcophagine based compounds of formula (I). The compounds can complex a radioisotope, such as 64-copper and hence are useful in radioimaging and radiotherapy of cancers, e.g. colorectal cancer. The compounds work via a pre-targeting imaging approach in which the tetrazine reacts via click chemistry with a functional group such as a transcyclooctene which is pre-bound to a ligand such as a tumour specific antibody.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: An apparatus relating to a component for a turbine engine which generates a hot gas fluid flow, and provides a cooling fluid flow. The component having a wall separating the hot gas fluid flow from the cooling fluid flow and having a heated surface along which the hot gas fluid flow flows and a cooled surface facing the cooling fluid flow. At least one cooling hole including a connecting passage extending from a first inlet located at the cooled surface, to a first outlet located at the heated surface, the connecting passage defining a downstream flow direction from the first inlet to the first outlet, the connecting passage comprising a metering section fluidly coupled to the first inlet and defining a metered centerline and a diffusing section, downstream of the metering section, defining a diffused centerline, and fluidly coupling the metering section to the first outlet.

Abstract: A graspable handle which incorporates a force indicator with attachment to secure said device to provide resistance for purposes of exercise.

Abstract: A packaging container is provided. The packaging container includes a body defining a volume. The body includes a neck extending from an opening of the body, and a base. A substrate is engageable with the neck to form a seal. The substrate defines at least one opening. A closure includes a projection engageable with the substrate. The projection defines at least one gap. In some embodiments, container systems and methods of manufacturing containers are disclosed.

Abstract: Tapered shafts for fluid pumps are disclosed. An example apparatus to pump fluid includes a gear, and a shaft including a taper to define a first portion of the shaft having a first thickness and a second portion of the shaft having a second thickness less than the first thickness, the second portion of the shaft between the gear and the first portion of the shaft.

Abstract: A polymer blend including 5 to 95 weight percent of a poly(ester-carbonate-carbonate) comprising 40 to 95 mole percent of ester units comprising low heat bisphenol groups and high heat bisphenol groups, wherein the ester units comprise 20 to 80 mole percent of the low heat bisphenol groups and 20 to 80 mole percent of the high heat bisphenol groups, based on the total moles of ester units in the poly(ester-carbonate-carbonate), and 5 to 60 mole percent of carbonate units comprising the low heat bisphenol groups and the high heat bisphenol groups, wherein the carbonate units comprise 20 to 80 mole percent of the low heat bisphenol groups and 20 to 80 mole percent of the high heat bisphenol groups, based on the total moles of carbonate units in the poly(ester-carbonate-carbonate); and 5 to 95 weight percent of a poly(etherimide), wherein the weight percent of each polymer is based on the total weight of the polymers in the blend, and a molded 0.

Abstract: L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates for treatment, amelioration and/or prevention of protein aggregation/tangles/plaques and diseases associated with protein aggregation/tangles/plaques. In particular, treatments and uses for L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates include Alzheimer's disease (AD), Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Huntington disease (HD).

Abstract: A system and method to efficiently configure an array of processing cores to perform functions of a program. A function of the program is converted to a configuration of cores. The configuration is laid out in a first subset of the array of cores. The configuration is stored. The configuration is replicated to perform the function on a second subset of the array of cores.

Abstract: A computer implemented method for controlling operational states of a hardware matching processor includes monitoring, by a circuit breaker, incoming electronic data transaction request messages to the hardware matching processor; dynamically defining a range of values as a function of values included with electronic data transaction request messages received during a rolling lookback window; detecting that an incoming electronic data transaction request message contains a value outside the range of values; transitioning the electronic data transaction processing system into a pre-open state for a predetermined period, thereby preventing the hardware matching processor from matching incoming electronic data transaction request messages; calculating a pre-open value at an end of the pre-open state; and re-opening the electronic data transaction processing system at the calculated pre-open value, thereby allowing the hardware matching processor to match incoming electronic data transaction request messages.

Abstract: A market planning system and associated methods are disclosed for dynamically generating an at least one local trade area and/or market planning area for an at least one business location. In at least one embodiment, a central computing system identifies a plurality of block groups proximal to the at least one business location. For each of the identified block groups, the computing system identifies at least one trade anchor located within said block group. The computing system defines a plurality of local trade areas based on the identified block groups and associated trade anchors, and subsequently defines an at least one market planning area based on the local trade areas.

Abstract: A computer implemented method for controlling operational states of a hardware matching processor includes monitoring, by a circuit breaker, incoming electronic data transaction request messages to the hardware matching processor; dynamically defining a range of values as a function of values included with electronic data transaction request messages received during a rolling lookback window; detecting that an incoming electronic data transaction request message contains a value outside the range of values; transitioning the electronic data transaction processing system into a pre-open state for a predetermined period, thereby preventing the hardware matching processor from matching incoming electronic data transaction request messages; calculating a pre-open value at an end of the pre-open state; and re-opening the electronic data transaction processing system at the calculated pre-open value, thereby allowing the hardware matching processor to match incoming electronic data transaction request messages.