Abstract: A method for using a needle assembly for an intradermal injection, and a drug delivery device is provided, which includes a needle cannula and a limiter surrounding the needle cannula and includes a skin engaging surface on the limiter. The limiter is moveable from a first position in which an elongate portion of the needle cannula is exposed for access to a medication vial, to a locked second position in which the limiter is not movable from the second position to the first position. In the second position, the needle tip extends beyond the skin engaging surface a distance of about 3 mm or less.

Abstract: An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. The device may include a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid.

Abstract: An intradermal delivery device for use in intradermally injecting substances into the skin of an animal includes a needle cannula supported by a hub portion that is attachable to a prefillable container. A limiter portion surrounds the needle cannula and extends away from the hub portion toward a forward tip of the needle cannula. The limiter portion includes a skin engaging surface extending in a plane generally perpendicular to an axis of the needle cannula. The skin engaging surface is received against skin of an animal to administer an intradermal injection. The forward tip extends beyond the skin engaging surface a distance that enables penetration of the needle cannula into the dermis layer of the skin of the animal enabling injection of the substance into the dermis layer of the animal. The device includes enclosure means that is moveable for concealing the needle cannula after the injection has been administered.

Abstract: Abstract of the Disclosure A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.

Abstract: The present invention relates to intradermal delivery of influenza vaccines, specific influenza formulations and methods for preparing and using them.

Abstract: A needle assembly for an intradermal injection device, and a drug delivery device, having a needle cannula having a needle tip and a limiter surrounding the needle cannula and having a skin engaging surface, wherein the limiter is moveable from a first position in which an elongate portion of the needle cannula is exposed, to a locked second position in which the limiter is not movable from the second position to the first position and in which the needle tip extends beyond the skin engaging surface a distance of about 3 mm or less.

Abstract: The present invention relates to methods and devices for intradermal delivery of substances, preferably therapeutic substances by targeting the substance to the intradermal compartment of a subject's skin. Substances delivered in accordance with the methods of the invention have an improved clinical utility and therapeutic efficacy relative to other drug delivery methods including intramuscular, and subcutaneous delivery. The present invention provides benefits and improvements over conventional drug delivery methods including but not limited to, improved pharmacokinetics and bioavailability.

Abstract: An intradermal needle assembly that is attachable to a prefillable container intended for intradermally injecting substances into an animal includes a needle cannula supported by a hub portion. The hub portion is adapted to receive the prefillable container just prior to administering the intradermal injection. A limiter portion surrounds the needle cannula and extends away from the hub portion toward a forward tip of the needle cannula, and includes a skin engaging surface with the needle cannula having a fixed angle of orientation, preferably generally perpendicular, relative to the plane of the skin engaging surface. The skin engaging surface is received against the skin of an animal to administer an intradermal injection. The forward tip extends beyond the skin engaging surface a distance enabling penetration of the needle cannula into the dermis layer of the skin of the animal enabling injection of the substance into the dermis layer.

Abstract: An intradermal needle assembly (10) for injecting a substance into the skin of an animal is disclosed. A hub (16) is attachable to a container (12) storing the substance. A needle (18) is supported by the hub (16) and has a forward tip (20) extending away from the hub (16). A limiter (22) surrounds the needle (18) and extends away from the hub (16) toward the forward tip (20) of the needle (18). The limiter (22) includes a generally flat skin engaging surface (24) extending in a plane generally perpendicular to an axis of the needle (18) and is adapted to be received against the skin (26) to administer an intradermal injection. The limiter (22) is movable between a first position (28), wherein the skin engaging surface (24) shields the needle (18), and a second position (30), wherein the forward tip (20) extends beyond the skin (26) upon depressing the skin engaging surface (24) against the skin (26).

Abstract: The present invention relates to methods and devices for intradermal delivery of substances, preferably therapeutic substances by targeting the substance to the intradermal compartment of a subject's skin. Substances delivered in accordance with the methods of the invention have an improved clinical utility and therapeutic efficacy relative to other drug delivery methods including intramuscular, and subcutaneous delivery. The present invention provides benefits and improvements over conventional drug delivery methods including but not limited to, improved pharmacokinetics and bioavailability.

Abstract: The present invention relates to methods for administration of a substance into the junctional layer of a subject's skin, i.e., a transitory tissue between the reticular dermis and the hypodermis of the subcutaneous layer of the skin. The present invention provides an improved method of parenteral drug delivery in that it provides among other benefits, minimized unwanted immune response and inadvertent immunotoxic effects provoked by the substance administered. In addition, an improved pharmacokinetic profile can be obtained by employing the methods of the present invention. Devices that can be used in accordance with the methods of the invention are also disclosed.

Abstract: A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.