Abstract: One variation of a system for generating thrust at an aerial vehicle includes: a primary electric motor; a rotor coupled to the motor; an internal-combustion engine; a disengagement mechanism interposed between the motor and an output shaft of the internal-combustion engine; an cooling shroud defining a shroud inlet between the rotor and the internal-combustion engine, extending over the internal-combustion engine, and defining a cooling shroud outlet opposite the rotor; a cooling fan coupled and configured to displace air through the cooling shroud; and a local controller configured to receive a rotor speed command specifying a target rotor speed, adjust a throttle setpoint of the internal-combustion engine according to the target rotor speed and a state of charge of a battery in the aerial vehicle, and drive the primary electric motor to selectively output torque to the rotor and to regeneratively brake the rotor according to the target rotor speed.

Abstract: A method is provided for using any repetitive athletic activity as software input via a motion sensor assembly removably affixed to any limb segment moved by the activity in repeating swings. Embodiments may generate statistics about the intended activity, such as repetition count and cadence (e.g. cycling RPM), for use in triggering software response. Further embodiments may dynamically calibrate for various sensor assembly positions and exercise types (e.g. on the thigh or ankle for leg-pedaling, or on the wrist or upper arm for arm-pedaling, all at any roll about the limb segment's proximal-to-distal axial dimension). Preferred embodiments may handle calibration covertly as the user operates the software's intended purpose (without an overt “calibration phase,” and without needing to request information from the user). Further embodiments may track an intended activity (e.g. leg-pedaling) while identifying other motions (e.g.

Abstract: Described herein are preserved formulations of insulin-Fc fusions. The formulations include insulin-Fc fusions having prolonged pharmacokinetic and pharmacodynamic profiles sufficient for once weekly administration in the treatment of diabetes and are sufficiently stable to allow for storage and use without unacceptable loss of chemical or physical stability.

Abstract: Systems and methods for configuring electronic fuses based on peripheral devices connected to a vehicle system are provided. The methods detect a first peripheral device has been connected to the vehicle system, receive a plurality of signals from the first peripheral device connected to the vehicle system, and configure a first electronic fuse based on the plurality of signals from the first peripheral device. The first electronic fuse is configured to electrically isolate the first peripheral device from the vehicle system upon receiving a current overload.

Abstract: Embodiments may be generally directed to a system for generating reactive acoustic energy for reducing acoustic noise in a chassis of an information handling system. A set of acoustically reactive elements may be positioned relative to a backplane comprising a plurality of backplane openings. Each acoustically reactive element comprises a plurality of walls and an acoustical energy reducing opening. The plurality of walls define an internal volume, wherein at least one wall is aligned parallel with a direction of airflow. The acoustical energy reducing opening may be oriented substantially parallel with the direction of the airflow and configured for the airflow passing the acoustically reactive element to pass the acoustical energy reducing opening to generate acoustic energy at a frequency based on the set of parameters of the acoustically reactive element.

Abstract: A computing chassis, including hard disk drives positioned at a first end of the chassis; a fan module positioned at a second end of the chassis; a first baffle having acoustic absorbing material, the first baffle extending between a first and a second side of the chassis, wherein the first and second sides of the chassis extend between the first and the second ends of the chassis, the first baffle spaced-apart from the fan module a first distance; a second baffle having acoustic absorbing material, the second baffle extending between the first and the second side of the chassis, the second baffle spaced-apart from the fan module a second distance greater than the first distance, wherein the first and the second baffle extend between the first and second sides of the chassis perpendicular to an airflow, and the acoustic absorbing material of the baffles attenuate acoustic waves.

Abstract: The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.

Abstract: Stable pharmaceutical formulations for therapeutic dual GLP-1 receptor/glucagon receptor agonists and methods of using such stable pharmaceutical formulations.

Abstract: A yogurt-based food product is packaged in a container, including a bottom wall and a sidewall, by depositing a mix-in in a center of the bottom wall and then driving the mix-in from the center of the bottom wall to the sidewall with a blast of gas. Afterwards, a dairy or plant-based product is deposited in the container. The mix-in is in contact with the bottom wall and the sidewall, and a height of the mix-in is greater at the sidewall than at a center point of the bottom wall.

Abstract: Embodiments may be directed to a codesigned shroud for a chassis comprising a plurality of components and a plurality of fans generating a plurality of airflows to cool the plurality of components. The codesigned shroud may have a plurality of walls defining a plurality of channels, wherein at least two walls of the plurality of walls define each channel of the plurality of channels. Each channel may be aligned with a direction of an airflow of the plurality of airflows. At least one channel includes a set of baffles oriented substantially perpendicular to the direction of an airflow in the channel. Each baffle may be formed with acoustically absorbent material to absorb acoustic energy that could affect performance of a component, wherein a first baffle of the set of baffles is offset from a second baffle of the set of baffles.

Abstract: The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.

Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and computing architectures and data models configured to facilitate management and performance of enterprise functions, and, more specifically, to an enterprise computing and data processing platform configured to implement applications and computerized tools configured to facilitate implementation of an enterprise data model to generate and manage component data objects representing enterprise tasks and processes, as well as portions thereof, any of which may be used to create and modify an enterprise data flow or a process flow, for example, using an enterprise computerized tool. In some examples, a method includes activating one or more applications as computerized tools to access subsets of one or more permissions, identifying an enterprise function data object to generate a third subset of permissions.

Abstract: A method includes decomposing, for each of a plurality of orthogonal slices, a set of PRF baseline images for the orthogonal slice into a set of baseline image features for the orthogonal slice; acquiring, using a magnetic imaging resonance (MRI) scanner of a MRI system based on a RF excitation pulse sequence for each of the plurality of orthogonal slices, a combined multi-encoded PRF treatment image; subtracting a weighted sum of the sets of baseline image features from the combined multi-encoded PRF treatment image to obtain a combined treatment-specific temperature information of the imaging region that provides multi-orthogonal slice temperature information associated with or resulting from treatment or thermal ablation of the imaging region of the patient after subtraction or removal of the baseline image features; and processing the combined treatment-specific temperature information to obtain slice-specific treatment-specific temperature information for each of the plurality of orthogonal slices.

Abstract: A method includes determining, during a calibration phase without application of ultrasound waves, a per-pixel magnetic field gradient of a magnetic field that is generated using a calibration drive signal applied to a magnetic coil; generating, during a treatment phase, a magnetic field gradient that is applied to a treatment area by using a treatment drive signal applied to the magnetic coil, wherein treatment drive signal is different from the calibration drive signal; determining, based on the treatment drive signal applied to the magnetic coil, per-pixel phases of a treatment image of the treatment area, wherein the per-pixel phases of the treatment image are based on spin displacement at each pixel resulting from the applied ultrasound waves; and adjusting, for each pixel of the treatment image, the per-pixel phases of the treatment image based on the per-pixel magnetic field gradient for a corresponding pixel, to obtain a gradient-adjusted treatment image.

Abstract: Embodiments of the invention are directed to a computer-implemented method of operating a data transmission system. The data transmission system includes a transmitter and a receiver. The computer-implemented method includes using the transmitter to send serialized data from the transmitter through a plurality of lanes to the receiver. The transmitter sends the serialized data at a first serialization ratio. The receiver is configured to receive and load the serialized data at a second deserialization ratio, wherein the first serialization ration is greater than the second deserialization ratio.

Abstract: Embodiments may be directed to a codesigned shroud for a chassis comprising a plurality of components and a plurality of fans generating a plurality of airflows to cool the plurality of components. The codesigned shroud may have a plurality of walls defining a plurality of channels, wherein at least two walls of the plurality of walls define each channel of the plurality of channels. Each channel may be aligned with a direction of an airflow of the plurality of airflows. At least one channel includes a set of baffles oriented substantially perpendicular to the direction of an airflow in the channel. Each baffle may be formed with acoustically absorbent material to absorb acoustic energy that could affect performance of a component, wherein a first baffle of the set of baffles is offset from a second baffle of the set of baffles.

Abstract: Embodiments may be generally directed to a system for generating reactive acoustic energy for reducing acoustic noise in a chassis of an information handling system. A set of acoustically reactive elements may be positioned relative to a backplane comprising a plurality of backplane openings. Each acoustically reactive element comprises a plurality of walls and an acoustical energy reducing opening. The plurality of walls define an internal volume, wherein at least one wall is aligned parallel with a direction of airflow.

Abstract: The disclosure provides an approach for inter-network command and control. Embodiments include receiving, by a proxy component of a service, from an agent of the service, a request to retrieve one or more action definitions. The agent may be located in a private networking environment, and the proxy component may be located in a networking environment external to the private networking environment. Embodiments include retrieving, by the proxy component, based on the request, the one or more action definitions from a queue associated with the service using a credential of the proxy component. Embodiments include providing, by the proxy component, the one or more action definitions to the agent. Embodiments include performing, by the agent, one or more actions within the private networking environment based on the one or more action definitions.