Patents by Inventor Paul Anthony GIBBONS

Paul Anthony GIBBONS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLO LIKE KINASE 4 INHIBITORS
    Publication number: 20240124426
    Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 18, 2023
    Publication date: April 18, 2024
    Inventors: Chudi NDUBAKU, Jared Thomas MOORE, Paul Anthony GIBBONS, Jae Hyuk CHANG, F. Anthony ROMERO, Xiaohui DU, Hiroyuki KAWAI, Stephane CIBLAT, Hong WANG, Vincent ALBERT, Lea CONSTANTINEAU-FORGET, Hugo de Almeida SILVA, Dilan Emine POLAT, Amit NAYYAR, Daniel Gordon Michael SHORE, Kejia WU, Joanne TAN
  • Polo like kinase 4 inhibitors
    Patent number: 11858915
    Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 27, 2023
    Date of Patent: January 2, 2024
    Assignee: ORIC PHARMACEUTICALS, INC.
    Inventors: Chudi Ndubaku, Jared Thomas Moore, Paul Anthony Gibbons, Jae Hyuk Chang, F. Anthony Romero, Xiaohui Du, Hiroyuki Kawai, Stephane Ciblat, Hong Wang, Vincent Albert, Lea Constantineau-Forget, Hugo De Almeida Silva, Dilan Emine Polat, Amit Nayyar, Daniel Gordon Michael Shore, Kejia Wu, Joanne Tan
  • POLO LIKE KINASE 4 INHIBITORS
    Publication number: 20230365537
    Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 27, 2023
    Publication date: November 16, 2023
    Inventors: Chudi NDUBAKU, Jared Thomas MOORE, Paul Anthony GIBBONS, Jae Hyuk CHANG, F. Anthony ROMERO, Xiaohui DU, Hiroyuki KAWAI, Stephane CIBLAT, Hong WANG, Vincent ALBERT, Lea CONSTANTINEAU-FORGET, Hugo de Almeida SILVA, Dilan Emine POLAT, Amit NAYYAR, Daniel Gordon Michael SHORE, Kejia WU, Joanne TAN
  • CYCLIC PEPTIDE ANTIBIOTICS
    Publication number: 20230025834
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of lipoprotein signal peptidase II (LspA), a key protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: September 10, 2021
    Publication date: January 26, 2023
    Applicant: Genentech, Inc.
    Inventors: Guosheng WU, Emily J. HANAN, Marie-Gabrielle BRAUN, Sharada S. LABADIE, Keira GARLAND, Richard M. PASTOR, Paul Anthony GIBBONS, Yuhong FU, Yun-Xing CHENG