Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.

Abstract: There is provided a coin handling apparatus which can be employed in public telephones and other coin fed apparatus. In a preferred embodiment the coin handling apparatus comprises a pocketed disc (100) arranged, in use, to cooperate with an entry portal (506) for receiveing coins and an exit portal (507) for dispensing coins, and drive means arranged, in use, to cause rotation of the pocketed disc (100), said drive means comprising a driving gear (200) and a driven gear (120) wherein the pocketed disc (100) comprises said driven gear (120), and the driving gear (200) is arranged such that it rotates the disc (100) in predetermined increments and rotation of the pocketed disc (100) can be paused between each incremental rotation.

Abstract: A shoebox coin changer has a coin inlet (8) to receive coins a coin acceptor (3) to discriminate between coins from the inlet and a coin sorter (4) to sort coins from the coin acceptor according to denomination. A plurality of coin hoppers (5) receive coins of respective different denominations from the coin sorter, to be paid out selectively by devices (6). The coins are stacked with a random disposition within the hoppers.

Abstract: A shoebox coin changer has a coin inlet (8) to receive coins a coin acceptor (3) to discriminate between coins from the inlet and a coin sorter (4) to sort coins from the coin acceptor according to denomination. A plurality of coin hoppers (5) receive coins of respective different denominations from the coin sorter, to be paid out selectively by devices (6). The coins are stacked with a random disposition within the hoppers.