Abstract: A system and method for separating the functions of a liquid chromatography (LC) system into physically separate systems that allow for a more versatile LC system, wherein an LC device provides a liquid solvent, a sample, and a pump and injector that pushes the sample in the solvent to an output port, and provides an attachable module containing a module input port, a column, and a heating unit on the column, with the module providing either transparent, non-transparent columns, or a combination of both, and the system providing an on-column detector within the module, or flow cell detectors in the module, the LC device or external to the module and the LC device, and attaching the module to the LC device using a high pressure compression connection that enables the sample in the solvent to be pumped through the column to at least one detector in order to separate, identify and quantify substances in the sample and transmit results from the at least one detector to a computing system for collection and analys

Abstract: A system and method for separating the functions of a liquid chromatography (LC) system into physically separate systems that allow for a more versatile LC system, wherein an LC device provides column 50 a liquid solvent, a sample, and a pump and injector that pushes the sample in the solvent to an output port, and providing an attachable module containing a module input port, a column, a heater for the column, and at least one detector for on-column detection, then attaching the module to the LC device using a press-fit connection that enables the sample in the solvent to be pumped through the column to the at least one detector in order to separate, identify and quantify substances in the sample and transmit results from the at least one detector to the LC system for collection and analysis.

Abstract: A system and method for separating the functions of a liquid chromatography (LC) system into physically separate systems that allow for a more versatile LC system, wherein an LC device provides column 50 a liquid solvent, a sample, and a pump and injector that pushes the sample in the solvent to an output port, and providing an attachable module containing a module input port, a column, a heater for the column, and at least one detector for on-column detection, then attaching the module to the LC device using a press-fit connection that enables the sample in the solvent to be pumped through the column to the at least one detector in order to separate, identify and quantify substances in the sample and transmit results from the at least one detector to the LC system for collection and analysis.

Abstract: A system and method for performing UV LED-based absorption detection for capillary liquid chromatography for detecting and quantifying compounds in a liquid, wherein a simplified system eliminates the need for a beam splitter and a reference cell by using a stable UV source, and power requirements are reduced, resulting in a portable and substantially smaller system with relatively low detection limits.

Abstract: A system and method for performing liquid chromatography for separating molecules in a liquid solution, wherein a single column includes two of more separation segments, each separation segment having a separate detector immediately after each separation segment, wherein a mobile phase is inserted into a first separation segment and moves through the column until passing through a last separation segment, and then using the data from the detectors to perform compound identification.

Abstract: A system and method for performing UV LED-based absorption detection for capillary liquid chromatography for detecting and quantifying compounds in a liquid, wherein a simplified system eliminates the need for a beam splitter and a reference cell by using a stable UV source, and power requirements are reduced, resulting in a portable and substantially smaller system with relatively low detection limits.

Abstract: A system and method for performing UV LED-based absorption detection for capillary liquid chromatography for detecting and quantifying compounds in a liquid, wherein a simplified system eliminates the need for a beam splitter and a reference cell by using a stable UV source, and power requirements are reduced, resulting in a portable and substantially smaller system with relatively low detection limits.

Abstract: A system and method for carrying out supercritical fluid extraction and gas chromatography simultaneously. Sample substances contained in solid (or liquid) matrices are extracted by means of supercritical fluid extraction and carried directly onto a thermal desorption modulator which functions as an interface between the extraction and chromatography systems. Analytes carried by the supercritical fluid are retained in the modulator while the fluid passes through during the cool cycle of the modulator. A thermal pulse raises the temperature of the modulator and releases retained substances, serving as a sharp injection of such substances into a fast separating column to provide high-speed separations. A complete chromatogram with reasonable resolution is generated within a few seconds time period. Thermal modulation signals at a fixed time interval are so chosen that the consequent chromatograms do not interfere with one another.

Abstract: A method and apparatus for element specific detection in chromatogragphic eluents. The apparatus is comprised of a radio frequency discharge between electrodes in helium, and utilizes a low-resolution plasma emission spectrometer to monitor selected spectral emissions produced when the helium discharge decomposes and excites the atomic constituents in chromatographic column effluents. The spectrometer is tuned to an atomic emission line in the near-infrared portion of the spectrum, and the emission intensity from the discharge region of a selected line is used to monitor the concentration of the element producing that line. Acceptable detector sensitivity is achieved by the use of a high-throughput optical system. Selectivity is achieved by a combination of correct line selection, plasma and carrier gas purification, and plasma gas doping.