Abstract: Systems and methods provide stimulation of peripheral targets such as targets in the lower limbs. Electrode arrays realized in circumferential or longitudinal embodiments have pads with horizontal and/or vertical offsets. Electrode array geometries are customizable and adaptable to individual users and treatment of different disorders. Novel systems of customization include software and hardware implemented solutions. A single device can provide treatment of two or more disorders or unwanted states using selected electrode geometries and stimulation protocols. Systems and methods for assessment of candidate stimulation sites and protocols use subjective or objective measures or both to determine which meet stimulation success criteria. Simulation is provided using transcutaneous, percutaneous, or implantable stimulators. A main advantage is the improved treatment of pelvic floor disorders, and especially overactive bladder (OAB).

Abstract: A neuromodulation system includes a conductive element, a magnetic field generator, a power module and a computer processor. The conductive element located internal a patient's body. At least a portion of the conductive element is positioned adjacent to a target tissue. The magnetic field generator is positioned external to the patient's body. The magnetic field generator generates a time varying magnetic field for inducing stimulation of the target tissue in combination with the conductive element to produce stimulation that is larger than that which would occur in the absence of the conductive element. The power module supplies power to the magnetic field generator. The computer processor controls the time varying magnetic field provided by the magnetic field generator according to at least one set of stimulation parameters.

Abstract: A method to treat a patient having a pelvic floor dysfunction or overactive bladder disorder by establishing a neurostimulator having a processor and an electrical signal generator to generate a stimulation signal. The processor is set to one or more parameters effective in the treating of the patient's pelvic disorder or dysfunction including overactive bladder disorder when the stimulation signal is applied to a saphenous nerve of the patient. The neurostimulator is configured to provide the stimulation signal to a stimulator in accordance with a stimulation protocol. At least one stimulator is positioned next to a portion of the saphenous nerve of at least one lower limb of a patient. The processor is operationally activated to provide the stimulation signal to the stimulator for treatment of the patient.

Abstract: A neurostimulation system is disclosed for providing treatment to a patient during a therapy session. The neurostimulation system includes a neurostimulator for transmitting magnetic or electrical signals based upon a treatment program. A programmer is connected to the neurostimulator to set a treatment session parameter value to calculate a therapy compliance value. A compliance module is connected to the neurostimulator and the programmer to calculate and store a therapy compliance value. A control module is connected to the compliance module, the programmer and the neurostimulator and determines whether the therapy compliance value is within a range of the treatment program. The neurostimulator transmits electrical or magnetic signals to the patient in a treatment session only if the therapy compliance value meets a compliance criteria.

Abstract: Methods and systems for improving nerve stimulation are disclosed which relate to shaping characteristics of the stimulation field such as by using different geometries and locations of stimulation. In embodiments, systems and methods are provided to improve selective modulation of specific targeted neural substrate, while minimizing the activation of adjacent non-targeted nervous tissue.

Abstract: Nerve stimulation systems and methods are disclosed for providing modulation of nerve targets in the lower limbs typically at or below the knee. For example, transcutaneous electrical nerve stimulation (TENS), percutaneous nerve stimulation, and implantable stimulation systems and methods are disclosed for providing stimulation to the saphenous nerve (SAFN). Additionally, systems and methods are provided for co-stimulating the posterior tibial nerve (PTN) and SAFN in combination with unique stimulation, and with control and display of OAB therapy protocols for multiple sites. Systems and methods of treatment can provide for management of usage and compliance monitoring, obtain and operating upon patient input responses to queries and management of payments and permissions related to provision of therapies for various disorders. Monitoring of usage and compliance can be managed both locally and remotely from a user. Stimulation provided in combination with a passive implantable component is also disclosed.

Abstract: Methods and systems for improving nerve stimulation are disclosed and are termed enhanced transcutaneous electrical stimulation (eTENS). One embodiment can be used for enhancing the excitation properties of neural tissue. In one embodiment, systems and methods are provided to enable the selective modulation of specific (targeted) neural substrate, while minimizing the activation of adjacent (non-targeted) nervous tissue, or differentially providing different modulation signals to tissue targeted by different implants. In one embodiment, the system consists of an implant that is used to modify the extracellular potential (i.e. activating function) generated by an independent electrical stimulus generator. Certain aspects of this technology can be applied to any part of the central and peripheral nervous systems. Particular embodiments of this technology provide for therapy related to urological disorders.

Abstract: A neuromodulation system includes a conductive element, a magnetic field generator, a power module and a computer processor. The conductive element located internal a patient's body. At least a portion of the conductive element is positioned adjacent to a target tissue. The magnetic field generator is positioned external to the patient's body. The magnetic field generator generates a time varying magnetic field for inducing stimulation of the target tissue in combination with the conductive element to produce stimulation that is larger than that which would occur in the absence of the conductive element. The power module supplies power to the magnetic field generator. The computer processor controls the time varying magnetic field provided by the magnetic field generator according to at least one set of stimulation parameters.

Abstract: Improved systems are disclosed for providing advantages during stimulation of peripheral nerves using transcutaneous, percutaneous, and implantable stimulators. Percutaneous stimulation is improved by accessories that guide the angel and depth of injection to allow for easy and controlled needle injection. Transcutaneous stimulation is improved using pressure to improve nerve recruitment. Systems and methods are disclosed for providing nerve stimulation of a patient to treat medical disorders and conditions within a single user or multiple user environments such as assisted living centers.

Abstract: Methods for providing therapy related to urological disorders. Particular embodiments of this technology relate to stimulation of lumbar spinal targets either alone or in combination with a sacral target or targets. In embodiments spinal roots are stimulated by partially or fully implanted stimulators to treat symptoms by producing bladder inhibition relative to that which occurs prior to stimulation. Embodiments also disclose improving nerve stimulation, including lumbar nerve root stimulation, using methods termed enhanced transcutaneous electrical stimulation (eTENS) since these enhance the inhibition or excitation of neural tissue.

Abstract: Nerve stimulation systems and methods are disclosed for providing improved compliance of a patient to a therapy regimen. Patient compliance is assessed and notification or treatment events can be scheduled, rescheduled or otherwise adjusted based upon patient compliance or non-compliance according to compliance rules and parameters of a treatment compliance module. Both compliance and non-compliance may lead to adjustment of the treatment regimen, scheduled treatment events, and notifications. Gamification of the treatment regimen allows users to obtain points that may be used to receive virtual awards, status awards, or monetary compensation of various forms. Monitoring of usage and compliance can be managed both locally and remotely from the user. Stimulation treatment, compliance monitoring, and gamification is disclosed for treatments using external or implanted stimulators, or the combination.

Abstract: Systems and methods provide notification to a user about pending neurostimulation or ongoing neurostimulation using a variety of notification signals and obtaining a user response to the notification using a variety of methods by which the user response is provided. Systems using implanted neurostimulation devices, external neurostimulators which provide transcutaneous electrical nerve stimulation, or both provide responsive and scheduled therapy regimens that include ecosystem support for augmenting user compliance when treating symptoms, conditions, or disorders. The system is also to assist the user through assessment protocols for improved customization of stimulus regimen attributes such as stimulation protocol parameter values, electrode montages, user surveying, and compliance contingent operations.

Abstract: Systems and methods provide stimulation of peripheral targets such as targets in the lower limbs. Electrode arrays realized in circumferential or longitudinal embodiments have pads with horizontal and/or vertical offsets. Electrode array geometries are customizable and adaptable to individual users and treatment of different disorders. Novel systems of customization include software and hardware implemented solutions. A single device can provide treatment of two or more disorders or unwanted states using selected electrode geometries and stimulation protocols. Systems and methods for assessment of candidate stimulation sites and protocols use subjective or objective measures or both to determine which meet stimulation success criteria. Simulation is provided using transcutaneous, percutaneous, or implantable stimulators. A main advantage is the improved treatment of pelvic floor disorders, and especially overactive bladder (OAB).

Abstract: A method to treat a patient having a pelvic floor dysfunction or overactive bladder disorder by establishing a neurostimulator having a processor and an electrical signal generator to generate a stimulation signal. The processor is set to one or more parameters effective in the treating of the patient's pelvic disorder or dysfunction including overactive bladder disorder when the stimulation signal is applied to a saphenous nerve of the patient. The neurostimulator is configured to provide the stimulation signal to a stimulator in accordance with a stimulation protocol. At least one stimulator is positioned next to a portion of the saphenous nerve of at least one lower limb of a patient. The processor is operationally activated to provide the stimulation signal to the stimulator for treatment of the patient.

Abstract: Methods for providing therapy related to urological disorders. Particular embodiments of this technology relate to stimulation of lumbar spinal targets either alone or in combination with a sacral target or targets. In embodiments spinal roots are stimulated by partially or fully implanted stimulators to treat symptoms by producing bladder inhibition relative to that which occurs prior to stimulation. Embodiments also disclose improving nerve stimulation, including lumbar nerve root stimulation, using methods termed enhanced transcutaneous electrical stimulation (eTENS) since these enhance the inhibition or excitation of neural tissue.

Abstract: A method to treat a patient having a pelvic floor dysfunction or disorder by establishing a neurostimulator having a processor and an electrical signal generator to generate a stimulation signal. The processor is set to one or more parameters effective in the treating of the patient's pelvic disorder or dysfunction when the stimulation signal is applied to a saphenous nerve of the patient. The neurostimulator is configured to provide the stimulation signal to a stimulator in accordance with a stimulation protocol. The stimulator is positioned below or at the level of the patient's knee and next to a portion of the saphenous nerve. The processor is operationally activated to provide the stimulation signal to the stimulator for treatment of the patient.

Abstract: Nerve stimulation systems and methods are disclosed for providing modulation of nerve targets in the lower limbs typically at or below the knee. For example, transcutaneous electrical nerve stimulation (TENS), percutaneous nerve stimulation, and implantable stimulation systems and methods are disclosed for providing stimulation to the saphenous nerve (SAFN). Additionally, systems and methods are provided for co-stimulating the posterior tibial nerve (PTN) and SAFN in combination with unique stimulation, and with control and display of OAB therapy protocols for multiple sites. Systems and methods of treatment can provide for management of usage and compliance monitoring, obtain and operating upon patient input responses to queries and management of payments and permissions related to provision of therapies for various disorders. Monitoring of usage and compliance can be managed both locally and remotely from a user. Stimulation provided in combination with a passive implantable component is also disclosed.

Abstract: A method to treat a patient having a pelvic floor dysfunction or disorder by establishing a neurostimulator having a processor and an electrical signal generator to generate a stimulation signal. The processor is set to one or more parameters effective in the treating of the patient's pelvic disorder or dysfunction when the stimulation signal is applied to a saphenous nerve of the patient. The neurostimulator is configured to provide the stimulation signal to a stimulator in accordance with a stimulation protocol. The stimulator is positioned below or at the level of the patient's knee and next to a portion of the saphenous nerve. The processor is operationally activated to provide the stimulation signal to the stimulator for treatment of the patient.

Abstract: One or more temporal stimulation parameters of vagus nerve stimulation (VNS) are selected to substantially modulate one or more target physiological functions without substantially modulating one or more non-target physiological functions. In one embodiment, a stimulation duty cycle is selected such that VNS is delivered to the cervical vagus nerve trunk to modulate a cardiovascular function without causing laryngeal muscle contractions.

Abstract: Methods and systems for providing therapy related to urological disorders which relate to stimulation of the saphenous nerve (SAFN) either alone or in combination with the posterior tibial nerve (PTN), medial plantar nerve (MPN) or lateral planar nerve. In embodiments nerves are stimulated by percutaneous, transcutaneous, and/or implanted stimulators. In embodiments the SAFN is stimulated below the level of the knee or near the medial malleolus. Embodiments also disclose improving nerve stimulation, including SAFN stimulation, using systems and methods termed enhanced transcutaneous electrical stimulation (eTENS) since these enhance the excitation of neural tissue. In an embodiment, systems and methods are provided to increase the chance of providing the selective modulation of specific (targeted) neural substrate, while decreasing the risk of activation of adjacent (non-targeted) nervous tissue.