Abstract: A speaker device includes a bass driver mounted in the internal space of an enclosure for generating a bass output. The bass driver has a central axis along which a piston area of the bass driver actuates oriented at an oblique angle relative to the bottom end of the enclosure to increase bass driver size and acoustic output and to reduce acoustic frequency distortion by providing a varying distance between the bass driver and the top and bottom ends of the enclosure. An elastomeric reflector-damper plate is spaced apart from the bass driver in the internal space in the enclosure. The reflector-damper plate radially disperses low to midrange audio frequencies of the bass output of the bass driver around the enclosure to further reduce acoustic frequency distortion. Electronic subsystems in the internal space coupled to the bass driver receive and process input audio signals to be rendered by the bass driver.

Abstract: The invention relates to compounds of formula (I) which are inhibitors of kinase activity, pharmaceutical formulations containing the compounds and their uses in treating and preventing viral infections and disorders caused or exacerbated by the viral infection wherein R1, R2, R3, R4a, R4b, R4c, R5, W, X, Y and Z are defined herein.

Abstract: The invention relates to compounds of formula (1) which are inhibitors of kinase activity, pharmaceutical formulations containing the compounds and their uses in treating and preventing viral infections and disorders caused or exacerbated by the viral infection wherein R1, R2, R3, R4a, R4b, R4c, R5, W, X, Y and Z are defined herein.

Abstract: A speaker device includes a bass driver mounted in the internal space of an enclosure for generating a bass output. The bass driver has a central axis along which a piston area of the bass driver actuates oriented at an oblique angle relative to the bottom end of the enclosure to increase bass driver size and acoustic output and to reduce acoustic frequency distortion by providing a varying distance between the bass driver and the top and bottom ends of the enclosure. An elastomeric reflector-damper plate is spaced apart from the bass driver in the internal space in the enclosure. The reflector-damper plate radially disperses low to midrange audio frequencies of the bass output of the bass driver around the enclosure to further reduce acoustic frequency distortion. Electronic subsystems in the internal space coupled to the bass driver receive and process input audio signals to be rendered by the bass driver.

Abstract: A data collecting device including a microcontroller communicatively coupled to at least one of a plurality of sensors, the sensors being configured to detect vital signs of a patient including at least one of temperature, blood oxygen saturation level, blood pressure, and a level of carbon dioxide exhaled by the patient, the microcontroller being configured to, in response to receiving data from at least one of the sensors, perform noise filtering and aggregate the received sensor data into a plurality of data packets, and transmit the filtered and aggregated data to portable mobile computing device communicatively coupled thereto.

Abstract: A networked speaker device includes a sealed housing and an Ethernet port in the housing for receiving power and audio data from a network router via an Ethernet cable. A power supply subsystem in the housing manages the power received at the Ethernet port. A microprocessor subsystem, powered by the power supply subsystem, receives and processes the audio data to generate output audio signals. A digital audio amplifier, powered by the power supply subsystem, amplifies the output audio signals to drive a speaker driver to render an audio output. The device also includes at least one heater resistor in the housing powered by the power supply subsystem. The at least one heater resistor is controlled by the microprocessor subsystem to automatically heat the interior of the housing when temperature inside the housing falls below a given temperature.

Abstract: The invention relates to compounds of formula (I) which are inhibitors of kinase activity, pharmaceutical formulations containing the compounds and their uses in treating and preventing viral infections and disorders caused or exacerbated by the viral infection wherein R1, R2, R3, R4a, R4b, R4c, R5, W, X, Y and Z are defined herein.

Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.

Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.

Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.

Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.

Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular Itk activity.

Abstract: The application discloses a hair styling implement 1 that comprises: a handle portion 3; and first 13 and second 17 styling parts, at least one of which is capable of being heated; wherein in a first operating mode one or both of said styling parts 13, 17 is or are moveable relative to at least part of said handle portion 3 to separate said styling parts 13, 17 so as to enable hair to be inserted therebetween for straightening; and in a second operating mode where said styling parts 13, 17 are adjacent hair can be wrapped around the periphery of the styling parts for curling.

Abstract: The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salts, solvates, stereoisomers thereof, R1 may be C1-C4 alkyl, aryl or heteroaryl, which may be substituted by one or more: halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano; R2 may be halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano, nitro; or aryl, heteroaryl or heterocycle, which may be substituted by one or more: halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano; or R2 may correspond to —O—R3; R3 is a 6-membered aromatic carbocyclic ring which may contain 1 or 2 nitrogen X is carbon or oxygen; Z is carbon or nitrogen; G is a fused 6-membered aromatic carbocyclic ring which may contain 1 or 2 nitrogen; m may be 0 or an integer ranging from 1 to 4; processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as NPY-Y5 receptor antagonists.

Abstract: A system and method is provided for operating an automated reward system through a financial institution over a network for merchants that have enrolled in the institution's reward program and for users that have a banking account at the institution associated with the reward program. The system includes a transaction module coupled to the institution for managing enrollment in and processing of purchase information associated with the program. The method includes receiving information at the institution about a first purchase by an enrolled user at an enrolled merchant; determining if the first purchase and the user qualified for such merchant's reward program; assigning monetary credit to the user's account in connection with such first purchase which may be applied towards a future purchase by the user at the enrolled merchant; receiving information at the institution about a second purchase by the user at the enrolled merchant; and applying the previous credit toward payment of the second purchase.

Abstract: A method carried out by processing a purchase by a user at a merchant; submitting purchase information to a financial institution; and assigning credit to the user according to the purchase and reward program terms tailored for the merchant.

Abstract: A stabilizer comprises a body having first and second ends, each of which is formed with a respective connector means, the body having an outer wall upon which is formed a plurality of the upstanding blades radially outer surfaces of which define gauge pads, flow channels being defined between adjacent ones of the blades, and at least one bridging region interconnecting two adjacent ones of the blades to form an enclosed passage communicating with an associated one of the flow channels, the bridging region having a surface defining part of an outer gauge surface of the stabilizer, the at least one bridging region being located intermediate and spaced from the first and second ends.

Abstract: An apparatus for predicting the reliability of an electronic system is provided. The apparatus includes at least one component, a stress sensor operable to measure stress of the at least one component, a resistance sensor operable to measure an electrical resistance of the at least one component, and an electronic control system coupled to the stress sensor and resistance sensor operable to predict the reliability of the electronic system using the stress and electrical resistance of the at least one component.

Abstract: A process and apparatus for controlling or reducing the heating value or BTU content of NGL recovered from LNG streams. LNG pipelines have a maximum allowable heating value that LNG must be within prior to entering the pipeline. If the LNG heating value is too high, the components contributing to the high heating value must be removed prior to being introduced in the pipeline. The process controls the heating value of the residue LNG gas stream by splitting a feed stream and warming at least a portion of the feed stream. Substantial differences in enthalpy content and temperature between the two portions of the feed stream exist prior to being sent to a fractionation tower.