Patents by Inventor Paul Blomquist
Paul Blomquist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12049658Abstract: The present invention is related to production of retinyl esters, such as in particular retinyl acetate, an important building block for production of vitamin A. The retinyl esters might be generated via enzymatic conversion of retinol which process includes the use of enzymes with acetyl-transferase (ATF) activity, thus acetylating retinol into retinol/retinyl acetate. Said process is particularly useful for biotechnological production of vitamin A.Type: GrantFiled: September 25, 2018Date of Patent: July 30, 2024Assignee: DSM IP Assets B.V.Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna Mcmahon, Joshua Trueheart, Celine Viarouge, René Marcel De Jong
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Publication number: 20240218336Abstract: The present invention is related to a novel enzymatic process for production of vitamin A alcohol (retinol) via conversion of retinal, which process includes the use of heterologous enzymes having activity as retinal reductase, particularly wherein the reaction leads to at least about 90% conversion of retinal into retinol. Said process is particularly useful for biotechnological production of vitamin A.Type: ApplicationFiled: February 13, 2024Publication date: July 4, 2024Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Patent number: 11905542Abstract: The present invention is related to a novel enzymatic process for production of retinyl esters, such as in particular retinyl long chain esters, via conversion of retinol, which process includes the use of enzymes having acyltransferase activity. Said process might be used for biotechnological production of vitamin A.Type: GrantFiled: September 25, 2018Date of Patent: February 20, 2024Assignee: DSM IP ASSETS B.V.Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna McMahon, Joshua Trueheart, Celine Viarouge
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Publication number: 20230227862Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.Type: ApplicationFiled: January 30, 2023Publication date: July 20, 2023Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Publication number: 20230112463Abstract: A tele-manufacturing system comprising a manufacturing environment containing equipment used for a manufacturing process; a plurality of sensors positioned within the manufacturing environment in proximity to the manufacturing equipment, wherein each sensor is configured to gather data from the manufacturing environment; at least one digitizer in communication with the sensors for receiving data from sensors and converting the data into one or more three-dimensional digital maps or point clouds; at least one processor in communication with the at least one digitizer, wherein the processor includes software for receiving and analyzing the digital maps or point clouds; and at least one manual controller in communication with the processor, wherein the manual controller receives motion input from a user, wherein the software on the processor mathematically transforms the motion input into corresponding motion commands that are sent to the manufacturing equipment by the processor, and wherein the manufacturing eqType: ApplicationFiled: October 8, 2021Publication date: April 13, 2023Inventors: Constance T. REICHERT LaMORTE, Paul A. BLOMQUIST
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Patent number: 11578344Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.Type: GrantFiled: September 25, 2018Date of Patent: February 14, 2023Assignee: DSM IP ASSETS B.V.Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna McMahon, Joshua Trueheart, Celine Viarouge
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Publication number: 20200277644Abstract: The present invention is related to a novel enzymatic process for production of vitamin A aldehyde (retinal) via stereoselective conversion of beta-carotene which process includes the use of trans-selective enzymes having activity as beta-carotene oxidases (BCOs), in particular having preference for trans-retinal. 5 Said process is in particular useful for biotechnological production of vitamin A.Type: ApplicationFiled: September 25, 2018Publication date: September 3, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE, René Marcel DE JONG
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Publication number: 20200248151Abstract: The present invention is related to a novel enzymatic process for production of vitamin A alcohol (retinol) via conversion of retinal, which process includes the use of heterologous enzymes having activity as retinal reductase, particularly wherein the reaction leads to at least about 90% conversion of retinal into retinol. Said process is particularly useful for biotechnological production of vitamin A.Type: ApplicationFiled: September 25, 2018Publication date: August 6, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Publication number: 20200239925Abstract: The present invention is related to production of retinyl esters, such as in particular retinyl acetate, an important building block for production of vitamin A. The retinyl esters might be generated via enzymatic conversion of retinol which process includes the use of enzymes with acetyl-transferase (ATF) activity, thus acetylating retinol into retinol/retinyl acetate. Said process is particularly useful for biotechnological production of vitamin A.Type: ApplicationFiled: September 25, 2018Publication date: July 30, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE, René Marcel DE JONG
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Publication number: 20200239924Abstract: The present invention is related to a novel enzymatic process for production of retinyl esters, such as in particular retinyl long chain esters, via conversion of retinol, which process includes the use of enzymes having acyltransferase activity. Said process might be used for biotechnological production of vitamin A.Type: ApplicationFiled: September 25, 2018Publication date: July 30, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Publication number: 20200231993Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.Type: ApplicationFiled: September 25, 2018Publication date: July 23, 2020Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
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Patent number: 7107118Abstract: A fully integrated automated laser weld process control system (LWPCS) and method of controlling the fabrication of structural parts, particularly for shipbuilding and other industries. The LWPCS defines joint and weld quality attributes as process control variables and integrates these weld quality variables, along with the more traditional process parameters such as laser power, wire feed, GMAW voltage and active seam tracking, into a closed-loop monitoring and control system. The LWPCS includes a central processor and a plurality of subsystems that control laser beam positioning, vision-based monitoring and image processing, active weld-quality monitoring and inspection, adaptive beam delivery, and seam tracking. Cross-communication between subsystems is managed by the central processor. In addition to process control, the system extracts weld quality attributes during the weld process and provides immediate documentation of the weld quality.Type: GrantFiled: June 3, 2004Date of Patent: September 12, 2006Assignee: Applied Thermal Sciences, Inc.Inventors: Nelson J. Orozco, Paul A. Blomquist, Kendrick H. Light, Robert B. Rudy, Steven R. Webber
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Publication number: 20050255568Abstract: Methods and compositions for amino acid production using genetically modified bacteria are disclosed.Type: ApplicationFiled: June 1, 2004Publication date: November 17, 2005Inventors: Richard Bailey, Paul Blomquist, Reed Doten, Edward Driggers, Kevin Madden, Jessica O'Leary, George O'Toole, Joshua Trueheart, Michael Walbridge, Peter Yorgey
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Publication number: 20040249495Abstract: A fully integrated automated laser weld process control system (LWPCS) and method of controlling the fabrication of structural parts, particularly for shipbuilding and other industries. The LWPCS defines joint and weld quality attributes as process control variables and integrates these weld quality variables, along with the more traditional process parameters such as laser power, wire feed, GMAW voltage and active seam tracking, into a closed-loop monitoring and control system. The LWPCS includes a central processor and a plurality of subsystems that control laser beam positioning, vision-based monitoring and image processing, active weld-quality monitoring and inspection, adaptive beam delivery, and seam tracking. Cross-communication between subsystems is managed by the central processor. In addition to process control, the system extracts weld quality attributes during the weld process and provides immediate documentation of the weld quality.Type: ApplicationFiled: June 3, 2004Publication date: December 9, 2004Inventors: Nelson J. Orozco, Paul A. Blomquist, Kendrick H. Light, Robert B. Rudy, Steven R. Webber