Abstract: A system and related method of filling tanks is provided so that tanks do not attain an overfill condition and/or so the tanks are filled to a maximum specified capacity. The system includes an adjustable float switch having a float configured to float in liquid that is filled into a trailer tanker, a mix tank, a frac tank, a storage tank and a variety of other tanks. The float can be set so that when the liquid attains a maximum level and associated volume, the float switch opens so that pressurized air can be communicated from it to a pneumatically actuated tanker valve disposed in a supply line. This shuts off the flow of liquid through the supply line and into the tank. The system can be operable in a various modes, such as a filling mode, a filled mode, a manual emergency shutoff mode and/or a manual reset mode.

Abstract: A system and related method of filling tanks is provided so that tanks do not attain an overfill condition and/or so the tanks are filled to a maximum specified capacity. The system includes an adjustable float switch having a float configured to float in liquid that is filled into a trailer tanker, a mix tank, a frac tank, a storage tank and a variety of other tanks. The float can be set so that when the liquid attains a maximum level and associated volume, the float switch opens so that pressurized air can be communicated from it to a pneumatically actuated tanker valve disposed in a supply line. This shuts off the flow of liquid through the supply line and into the tank. The system can be operable in a various modes, such as a filling mode, a filled mode, a manual emergency shutoff mode and/or a manual reset mode.

Abstract: The present invention relates to methods and pharmaceutical compositions for treating breast cancers. In particular, the present invention relates to a method for predicting the survival of a patient suffering from a breast cancer comprising i) determining the expression level of Vangl2 in a tumor sample obtained from the patient, ii) comparing the expression level determined at step i) with a predetermined reference value and iii) providing a poor prognosis when the expression level determined at step i) is higher than the predetermined reference value. The present invention also relates to a method for treating a patient suffering from a breast cancer comprising the steps consisting of i) predicting the survival of the patient according to claim 1 and ii) administering the patient with an anti-Vangl2 antibody or an inhibitor of Vangl2 expression or an inhibitor of the Vangl2-p62 interaction when it is concluded that the patient has a poor prognosis at step i).

Abstract: The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying breast cancer status in a patient. In particular, the biomarkers of this invention are useful to determine metastasis-free survival of breast cancer patients. The biomarkers can be detected by SELDI mass spectrometry in serum samples fractionated by means of anion exchange chromatography. Some of the biomarkers have been identified as: Apolipoprotein A1; Apolipoprotein A2; Haptoglobin alpha 1; Transferrin; Complement C3a; and truncated forms thereof.

Abstract: The invention concerns a novel gene, coding for a protein named Erbin (Erbb2 Interacting protein), which interacts with the intracellular part of ERBB2/HER-2 receptors, involved in particular in the development of cancers, the diagnostic and therapeutic uses of novel nucleotide sequences and identified amino acids.

Abstract: Methods and apparatus are disclosed for cleaning storage containers used in petrochemical or oil refineries. A remotely controllable dual tracked robotic vehicle is placed in a container to be cleaned. A cleaning fluid diluent material is directed against waste material in the container causing a portion of it to form a slurry which is vacuumed out by a nozzle and hose carried by the vehicle. A separator system exterior to the tank processes the removed slurry.