Abstract: A prediction and stimulation system or method is provided for neurological disorders characterized by a local dysfunction in neuronal activity regulation. An array of electrodes detects neuronal electrical activity of selected brain region. A detection module detects in each electrode changes in electric field and neuronal activity. A prediction module predicts for each electrode abnormal regimes determined by neurological disorder. A neuromodulation module interfaced with the electrodes selects one or more electrodes in the array where a predefined threshold has been exceeded and stimulates the brain region through each of these selected electrodes using an intermittent therapeutic stimulation pattern with a frequency between 150 and 200 Hz. The provided therapy allows for seizure prediction and detection with high accuracy, potential low risk and increased battery life.

Abstract: A prediction and stimulation system or method is provided for neurological disorders characterized by a local dysfunction in neuronal activity regulation. An array of electrodes detects neuronal electrical activity of selected brain region. A detection module detects in each electrode changes in electric field and neuronal activity. A prediction module predicts for each electrode abnormal regimes determined by neurological disorder. A neuromodulation module interfaced with the electrodes selects one or more electrodes in the array where a predefined threshold has been exceeded and stimulates the brain region through each of these selected electrodes using an intermittent therapeutic stimulation pattern with a frequency between 150 and 200 Hz. The provided therapy allows for seizure prediction and detection with high accuracy, potential low risk and increased battery life.