Patents by Inventor Paul Burns
Paul Burns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9957478Abstract: A carrier for expansion of pluripotent stem cells is provided, wherein the carrier comprises a substrate comprising one or more outer surfaces, wherein the one or more outer surfaces are modified with gas plasma treatment, and one or more structured indentations on one or more of the outer surfaces. The carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.05 mm to 1.2 mm and each of the structured indentations has a major axis in a range from about 0.1 mm to 0.5 mm, a minor axis in a range from about 0.1 mm to 0.5 mm and a depth in a range from about 0.025 mm to about 0.5 mm. A method of making the carrier, and culturing stromal cells using the same carrier are also provided.Type: GrantFiled: November 7, 2016Date of Patent: May 1, 2018Assignee: GENERAL ELECTRIC COMPANYInventors: Brian Michael Davis, Evelina Roxana Loghin, Kenneth Roger Conway, Andrew Arthur Paul Burns, David Gilles Gascoyne
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Patent number: 9926523Abstract: A carrier for growing stem cells is provided, the carrier comprises a substrate comprising one or more outer surfaces; and a hydrophilic, water soluble coating material disposed and dried on one or more of the outer surfaces. The carrier comprises one or more structured indentations on one or more of the outer surfaces, wherein the carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.05 mm to 1.2 mm and each of the structured indentations has a major axis in a range from about 0.1 mm to 0.5 mm, a minor axis in a range from about 0.1 mm to 0.5 mm and a depth in a range from about 0.025 mm to about 0.5 mm. A method of culturing stem cells and stromal cells using the same carrier are also provided.Type: GrantFiled: March 15, 2013Date of Patent: March 27, 2018Assignee: GENERAL ELECTRIC COMPANYInventors: Andrew Arthur Paul Burns, David Gilles Gascoyne, Scott Michael Miller
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Publication number: 20170181208Abstract: A method of controlling a vehicle entertainment unit mounted in a vehicle using a center stack control system of the vehicle includes establishing a BLUETOOTH connection between the center stack control system and the vehicle entertainment unit, retrieving metadata from the vehicle entertainment unit, transmitting the metadata from the vehicle entertainment unit to the center stack control system via the BLUETOOTH connection, receiving a control command at the vehicle entertainment unit via the BLUETOOTH connection, mapping the control command to a corresponding function of the vehicle entertainment unit at the vehicle entertainment unit, and executing the corresponding function at the vehicle entertainment unit.Type: ApplicationFiled: March 6, 2017Publication date: June 22, 2017Inventor: RICHARD PAUL BURNS
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Patent number: 9638653Abstract: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g.Type: GrantFiled: May 12, 2015Date of Patent: May 2, 2017Assignee: General Electricity CompanyInventors: Radislav Alexandrovich Potyrailo, Cheryl Margaret Surman, Andrew Arthur Paul Burns, Nandini Nagraj
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Publication number: 20170108420Abstract: Provided herein are methods and systems for rapid testing of films used in the manufacture of bioprocess bags. The methods described herein allow for determination of resistance to flexural fatigue while mimicking actual conditions in bioprocesses such as flexion and subsequent fatigue and failure of a bioprocess bag made of a film when it is placed on a rocking platform.Type: ApplicationFiled: August 8, 2016Publication date: April 20, 2017Inventors: Andrew Arthur Paul Burns, Eugene Pauling Boden, Scott Michael Miller, Kathryn Amanda Misner, Terry Lee Saunders, Donald Joseph Buckley, JR.
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Patent number: 9591432Abstract: A method of controlling a vehicle entertainment unit mounted in a vehicle using a center stack control system of the vehicle includes establishing a BLUETOOTH connection between the center stack control system and the vehicle entertainment unit, retrieving metadata from the vehicle entertainment unit, transmitting the metadata from the vehicle entertainment unit to the center stack control system via the BLUETOOTH connection, receiving a control command at the vehicle entertainment unit via the BLUETOOTH connection, mapping the control command to a corresponding function of the vehicle entertainment unit at the vehicle entertainment unit, and executing the corresponding function at the vehicle entertainment unit.Type: GrantFiled: January 2, 2015Date of Patent: March 7, 2017Assignee: VOXX INTERNATIONAL CORPORATIONInventor: Richard Paul Burns
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Publication number: 20170051248Abstract: A carrier for expansion of pluripotent stem cells is provided, wherein the carrier comprises a substrate comprising one or more outer surfaces, wherein the one or more outer surfaces are modified with gas plasma treatment, and one or more structured indentations on one or more of the outer surfaces. The carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.05 mm to 1.2 mm and each of the structured indentations has a major axis in a range from about 0.1 mm to 0.5 mm, a minor axis in a range from about 0.1 mm to 0.5 mm and a depth in a range from about 0.025 mm to about 0.5 mm. A method of making the carrier, and culturing stromal cells using the same carrier are also provided.Type: ApplicationFiled: November 7, 2016Publication date: February 23, 2017Inventors: Brian Michael Davis, Evelina Roxana Loghin, Kenneth Roger Conway, Andrew Arthur Paul Burns, David Gilles Gascoyne
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Publication number: 20170035914Abstract: Disclosed are novel cell-penetrating transporters for enhancing cellular uptake of peptide fusion proteins into live cells. The cell-penetrating transporters comprise a functionalized peptide construct comprising a cell importation peptide covalently bound to a cargo, the cell importation peptide in an unreactive monomeric form, and a pharmaceutical carrier. In certain embodiments, the cargo further comprises a nuclear localization sequence (NLS) allowing the cargo to be transported across the nuclear membrane.Type: ApplicationFiled: August 5, 2015Publication date: February 9, 2017Inventors: Erik Leeming Kvam, Michael James Rishel, Andrew Arthur Paul Burns
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Publication number: 20170022550Abstract: The present disclosure relates to a sample assessment device. By way of example, the sample assessment device may include a substrate including a sample application region; an amplification region comprising a plurality of amplification reagents; a waste region comprising an entrance fluidically coupled to the amplification region and extending away from the amplification region; and a detection region spaced apart from the amplification region. The sample assessment device may also include a valve coupled to the substrate and configured to separate the amplification region from the detection region in a closed configuration, wherein the amplification region and the valve are positioned on the sample assessment device between the sample application region and the detection region and wherein the sample assessment device is configured to permit lateral flow from the amplification region to the detection region when the valve is in an open configuration.Type: ApplicationFiled: July 23, 2015Publication date: January 26, 2017Inventors: David Roger Moore, Matthew Jeremiah Misner, Andrew Arthur Paul Burns, John Bishop, Lisa K. Lafleur, Maxwell Wheeler
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Patent number: 9534206Abstract: A carrier for expansion of induced pluripotent stem cells is provided, wherein the carrier comprises a substrate comprising one or more outer surfaces, wherein the one or more outer surfaces are modified with gas plasma treatment, and one or more structured indentations on one or more of the outer surfaces. The carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.05 mm to 1.2 mm and each of the structured indentations has a major axis in a range from about 0.1 mm to 0.5 mm, a minor axis in a range from about 0.1 mm to 0.5 mm and a depth in a range from about 0.025 mm to about 0.5 mm. A method of making the carrier, and culturing induced pluripotent stem cells using the same carrier are also provided.Type: GrantFiled: August 18, 2014Date of Patent: January 3, 2017Assignee: General Electric CompanyInventors: Brian Michael Davis, Kenneth Roger Conway, Evelina Roxana Loghin, Andrew Arthur Paul Burns, David Gilles Gascoyne, Scott Michael Miller
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Patent number: 9518249Abstract: A carrier for expansion of pluripotent stem cells is provided, wherein the carrier comprises a substrate comprising one or more outer surfaces, wherein the one or more outer surfaces are modified with gas plasma treatment, and one or more structured indentations on one or more of the outer surfaces. The carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.05 mm to 1.2 mm and each of the structured indentations has a major axis in a range from about 0.1 mm to 0.5 mm, a minor axis in a range from about 0.1 mm to 0.5 mm and a depth in a range from about 0.025 mm to about 0.5 mm. A method of making the carrier, and culturing stromal cells using the same carrier are also provided.Type: GrantFiled: March 15, 2013Date of Patent: December 13, 2016Assignee: GENERAL ELECTRIC COMPANYInventors: Brian Michael Davis, Evelina Roxana Loghin, Kenneth Roger Conway, Andrew Arthur Paul Burns, David Gilles Gascoyne
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Patent number: 9470445Abstract: A head pressure control system may control a high side operating condition of a vapor compression system. The head pressure control system includes a vapor compression system having a compressor, condenser, expansion valve, and evaporator. The head pressure control system may also include a high side condition sensor, a low side condition sensor, a controller, and a control device. The low side condition sensor may measure and communicate a low side operating condition to the controller. The high side condition sensor may measure and communicate a high side operating condition to the controller. The controller may compare a theoretical high side operating condition to the high side operating condition, and determine a control output. The controller may communicate the control output to a control device, which may influence the high side operating condition based on the control output.Type: GrantFiled: November 7, 2014Date of Patent: October 18, 2016Assignee: Emerson Climate Technologies, Inc.Inventor: Nathan Paul Burns
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Publication number: 20160223484Abstract: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g.Type: ApplicationFiled: May 12, 2015Publication date: August 4, 2016Inventors: Radislav Alexandrovich Potyrailo, Cheryl Margaret Surman, Andrew Arthur Paul Burns, Nandini Nagraj
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Patent number: 9399523Abstract: A method of operating an aircraft comprising a cockpit with a flight deck having at least one flight display, a pilot's seat facing the flight deck, and a synthetic vision system producing a synthetic image for displaying on the at least one flight display.Type: GrantFiled: February 28, 2014Date of Patent: July 26, 2016Assignee: GENERAL ELECTRIC COMPANYInventors: Timothy Donal Paul Burns, Dashiell Matthews Kolbe, Norman Leonard Ovens
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Publication number: 20160198288Abstract: A method of controlling a vehicle entertainment unit mounted in a vehicle using a center stack control system of the vehicle includes establishing a BLUETOOTH connection between the center stack control system and the vehicle entertainment unit, retrieving metadata from the vehicle entertainment unit, transmitting the metadata from the vehicle entertainment unit to the center stack control system via the BLUETOOTH connection, receiving a control command at the vehicle entertainment unit via the BLUETOOTH connection, mapping the control command to a corresponding function of the vehicle entertainment unit at the vehicle entertainment unit, and executing the corresponding function at the vehicle entertainment unit.Type: ApplicationFiled: January 2, 2015Publication date: July 7, 2016Inventor: RICHARD PAUL BURNS
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Publication number: 20160131405Abstract: A head pressure control system may control a high side operating condition of a vapor compression system. The head pressure control system includes a vapor compression system having a compressor, condenser, expansion valve, and evaporator. The head pressure control system may also include a high side condition sensor, a low side condition sensor, a controller, and a control device. The low side condition sensor may measure and communicate a low side operating condition to the controller. The high side condition sensor may measure and communicate a high side operating condition to the controller. The controller may compare a theoretical high side operating condition to the high side operating condition, and determine a control output. The controller may communicate the control output to a control device, which may influence the high side operating condition based on the control output.Type: ApplicationFiled: November 7, 2014Publication date: May 12, 2016Applicant: EMERSON CLIMATE TECHNOLOGIES, INC.Inventor: NATHAN PAUL BURNS
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Publication number: 20160002621Abstract: A method is provided herein, the method includes: applying a sample comprising target nucleic acids to a sample application zone of a substrate; and flowing a nucleic acid amplification reaction mixture across a length of the substrate through the sample application zone to amplify the target nucleic acid forming a nucleic acid amplification product; wherein the target nucleic acid having a first molecular weight is substantially immobilized at the sample application zone and wherein the amplification product having a second molecular weight migrates away from the sample application zone. An associated device is also provided.Type: ApplicationFiled: July 1, 2014Publication date: January 7, 2016Inventors: John Richard Nelson, David Roger Moore, Robert Scott Duthie, Matthew Jeremiah Misner, Gregory Andrew Grossmann, Elizabeth Marie Dees, Patrick McCoy Spooner, Erik Leeming Kvam, Andrew Arthur Paul Burns, Vicki Herzl Watkins
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Patent number: 9037418Abstract: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g.Type: GrantFiled: September 19, 2013Date of Patent: May 19, 2015Assignee: General Electric CompanyInventors: Radislav Alexandrovich Potyrailo, Cheryl Margaret Surman, Andrew Arthur Paul Burns, Nandini Nagraj
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Publication number: 20150118441Abstract: The present disclosure provides a multi-layer thermal protection material comprising: (i) a substrate layer; (ii) a reflection layer formed on the substrate layer; and (iii) an emission layer formed on the reflection layer and effective to convert thermal energy to photonic energy. The reflection layer comprises a porous scattering media effective to reflect photonic energy away from the substrate layer. The emission layer comprises a thermally emissive dopant incorporated into a thermal matrix material. The present disclosure also provides articles such as portions of hypersonic flight vehicles and turbine component parts that include coatings comprising the multi-layer protection material of the present disclosure. The present disclosure also provides methods of making and using the multi-layer thermal protection material and associated articles described herein.Type: ApplicationFiled: October 25, 2013Publication date: April 30, 2015Applicant: GENERAL ELECTRIC COMPANYInventors: Wen Shang, Tao DENG, Boris RUSS, Hendrik Pieter Jacobus DE BOCK, Adam RASHEED, Andrew Arthur Paul BURNS, Mohamed SAKAMI, Steven Charles ACETO, Andrey MESHKOV, Scott Michael MILLER
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Patent number: D795042Type: GrantFiled: January 28, 2016Date of Patent: August 22, 2017Inventor: Michael Paul Burns