Abstract: A current sensor integrated circuit (IC) includes a unitary lead frame having at least one first lead having a terminal end, at least one second lead having a terminal end, and a paddle having a first surface and a second opposing surface. A semiconductor die is supported by the first surface of the paddle, wherein the at least one first lead is electrically coupled to the semiconductor die and the at least one second lead is electrically isolated from the semiconductor die. The current sensor IC further includes a first mold material configured to enclose the semiconductor die and the paddle and a second mold material configured to enclose at least a portion of the first mold material, wherein the terminal end of the at least one first lead and the terminal end of the at least one second lead are external to the second mold material.

Abstract: An electrosurgical instrument having a microwave ablation antenna dimensioned to be suitable for insertion into a pancreas via a surgical scoping device, to provide a rapid and accurate alternative to known RF ablation techniques. The instrument comprises a radiating tip portion connected at a distal end of a flexible coaxial cable that conveys microwave energy. The radiating tip portion comprises a proximal coaxial transmission line for conveying the microwave energy and a distal needle tip mounted at a distal end of the coaxial transmission line, wherein the distal needle tip operates as a half wavelength transformer. The length of the radiating tip portion may be in the range from 5 mm to 80 mm.

Abstract: An archery arrow end includes a main body that has a first end and a second end. The main body defines a longitudinal axis. The archery arrow end includes a tip positioned at the first end. The tip has a blunt end. The archery arrow end includes an arrow shaft connector positioned at the second end. The arrow shaft connector is configured to be attached to an arrow shaft. The archery arrow end includes flexible wings that extend from the main body in a direction at least partially toward the second end. Each wing has a free end configured to move toward and away from the longitudinal axis.

Abstract: Methods and systems are provided for a medical imaging system having a detector array. In one example, the detector array may include a plurality of adjustable imaging detectors arranged in subsets thereof, each of the plurality of adjustable imaging detectors including a detector unit, each detector unit having a plurality of rows of detector modules, wherein the plurality of adjustable imaging detectors may be arranged on an annular gantry, where an inner surface of the annular gantry may circumscribe a substantially rectangular aperture therethrough, and wherein each subset of the plurality of adjustable imaging detectors may be respectively disposed on a side of the inner surface and may extend within the substantially rectangular aperture.

Abstract: Disclosed herein are compositions and methods for preventing, ameliorating, or treating Clostridium difficile infections and/or reducing the severity of one or more risk factors, signs, or symptoms associated with C. difficile infections. In particular, the technology of the present disclosure relates to methods for administering an effective amount of a composition comprising strains of Bacillus amyloliquefaciens bacteria identified as ART24, ART4, and ART 12, to a subject suffering from or at risk for C. difficile infections.

Abstract: A gear-driven infusion assembly is provided which has a housing, a gear assembly coupled to the housing, a shuttle assembly slidably coupled to the housing and operably coupled to the gear assembly, and a tube enclosure connected to the housing. The tube enclosure is configured to house a primary drug closure. The gear assembly includes a spool assembly having a pinion gear and a drive spool. When the spring rotates the drive spool, the drive spool drives the pinion gear, and the gear assembly drives the shuttle assembly. When the gear assembly drives the shuttle assembly, the shuttle assembly slides longitudinally along the housing. The gear assembly may be spring driven such that a spring rotates the pinion gear about the drive spool. The primary drug closure may be a syringe. An overspeed protection device is also provided which has a spool assembly including a drive spool having a plurality of cams, a spring, and a pinion gear with spiral cam surfaces.

Abstract: In a method for MRI of an object, spins of a first material and spins of a second material are excited. An in-phase echo signal is acquired when the spins are in-phase and an out-of-phase echo signal is acquired, when the spins are out of phase. A first image for the first material and/or a second image for the second material is generated by a computing unit depending on the in-phase echo signal and the out-of-phase echo signal. For acquiring the out-of-phase echo signal, a momentum space is sampled asymmetrically in a read-out direction.

Abstract: A DPE memristor crossbar array system includes a plurality of partitioned memristor crossbar arrays. Each of the plurality of partitioned memristor crossbar arrays includes a primary memristor crossbar array and a redundant memristor crossbar array. The redundant memristor crossbar array includes values that are mathematically related to values within the primary memristor crossbar array. In addition, the plurality of partitioned memristor crossbar arrays includes a block of shared analog circuits coupled to the plurality of partitioned memristor crossbar arrays. The block of shared analog circuits is to determine a dot product value of voltage values generated by at least one partitioned memristor crossbar array of the plurality of partitioned memristor crossbar arrays.

Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.

Abstract: The illuminator device for medical examination described herein employs a housing incorporating a magnified viewing lens having a lens polarizer and an array of LEDs to provide light for the viewing organic tissue and other matter. A switch is provided to communicate with a microprocessor that controls an LED driver adapted initiate to provide modes of operation that provide certain of the LEDs being illuminated in different modes. In operation the device incorporates at least five modes of operation. A first mode provides activating only polarized white lights, a second mode provides activating only ZWB2 bandpass filtered 365 nm UV LEDs, a third mode provides activating only ZWB2 bandpass filtered 385 nm UV LEDs, a fourth mode provides activating only unfiltered 405 nm UV LEDs and a fifth mode comprises activating only ZWB2 bandpass filtered 365 nm UV LEDs and ZWB2 bandpass filtered 385 nm UV LEDs. The device additionally incorporates an auxiliary magnifier that stores in the device handle.

Abstract: Electrosurgical lysing methods. In some implementations, the method may comprise delivering a lysing tip through an entrance incision into a patient's body, wherein the lysing tip comprises at least one bead comprising an at least substantially electrically non-conductive surface; and at least one lysing segment extending within a recess defined, at least in part, by the at least one bead. The at least one bead may protrude both distally and proximally relative to the at least one lysing segment. The method may further comprise forming opposing tissue planes using the lysing tip to create an implant pocket; and inserting an implant through the entrance incision and into the implant pocket.

Abstract: The present disclosure relates to the identification of a subject that is affected with, or predisposed to, autism or to one or more autism spectrum disorders (ASD). The present disclosure includes methods related to the association of certain genetic markers with autism and/or ASD. More particularly, the present disclosure is related to methods and diagnostic tests for diagnosing or predicting ASD in an individual.

Abstract: Methods and systems are provided for a medical imaging system having a detector array. In one example, the detector array may include a plurality of adjustable imaging detectors, each of the plurality of adjustable imaging detectors including a detector unit, each detector unit having a plurality of rows of detector modules, wherein the plurality of adjustable imaging detectors may be arranged on an annular gantry, the annular gantry configured for rotation about an axis of a cylindrical aperture of the annular gantry, the axis extending a length of the cylindrical aperture, and wherein each of the plurality of adjustable imaging detectors may be disposed within the cylindrical aperture and may extend orthogonally toward the axis.

Abstract: A needle or stylet has a tip contour with a reverse back bevel curved toward the longitudinal axis of the needle or stylet. The needle has a flexible intermediate portion and/or a two-part construction in which a distal portion of the needle to crimped onto a proximal portion of the needle. The needle or a stylet is combined with a spring mechanism in the hub of the needle or stylet assembly. The spring mechanism positions the tip of the needle or stylet in a middle position extending from the distal end of the assembly, allows the needle or stylet to be moved into a spring loaded fully retracted configuration within the assembly as the septal wall is tented, and then releasing the spring loaded needle or stylet as the needle or stylet penetrates the septal wall. A method of using a needle or stylet with a spring mechanism is included.

Abstract: A lithographic apparatus having a substrate table, a projection system, an encoder system, a measurement frame and a measurement system. The substrate table has a holding surface for holding a substrate. The projection system is for projecting an image on the substrate. The encoder system is for providing a signal representative of a position of the substrate table. The measurement system is for measuring a property of the lithographic apparatus. The holding surface is along a plane. The projection system is at a first side of the plane. The measurement frame is arranged to support at least part of the encoder system and at least part of the measurement system at a second side of the plane different from the first side.

Abstract: Examples are disclosed that relate to managing workloads provided by a plurality of clients to a shared resource. One example provides a computing device comprising a processor and a storage device storing instructions executable by the processor. The instructions are executable to provide a first workload from a first client and a second workload from a second client to a shared memory accessible by the first client, the second client, and a resource configured to process the first workload and the second workload. The computing device is configured to determine that an exception has occurred while processing the first workload, and to take an action to prevent execution of at least some additional work from the first client. The instructions are further executable to receive a result of processing the second workload after taking the action to prevent the execution of the additional work.

Abstract: In an example implementation according to aspects of the present disclosure, a method may include detecting, by a computing device, termination of a wired connection via a connector, after a module is detached from a cavity of the computing device, and automatically switching from the wired connection to a wireless connection between the module and the computing device, to maintain the data communications between the module and the computing device.

Abstract: A computer-assisted device includes a plurality of articulated arms and a control unit. Each articulated arm has a plurality of brakes. The control unit is configured to determine a plurality of timing windows based on a time period for brake release and a number of articulated arms comprising the plurality of articulated arms. The plurality of timing windows include a timing window for each articulated arm of the plurality of articulated arms. The control unit is further configured to determine, for each articulated arm of the plurality of articulated arms, an order for releasing brakes of the plurality of brakes of that articulated arm. The control unit is further configured to cause release of the brakes of the plurality of brakes of each of the plurality of articulated arms according to the determined order and the plurality of timing windows.

Abstract: Compounds are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.

Abstract: The present invention provides a device and method for an integrated white colored electromagnetic radiation source using a combination of laser diode excitation sources based on gallium and nitrogen containing materials and light emitting source based on phosphor materials. In this invention a violet, blue, or other wavelength laser diode source based on gallium and nitrogen materials is closely integrated with phosphor materials, such as yellow phosphors, to form a compact, high-brightness, and highly-efficient, white light source.