Patents by Inventor Paul C. Grint

Paul C. Grint has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of hepatitis C virus infections with interleukin-10
    Patent number: 6685931
    Abstract: The hepatoprotective effect of IL-10 is described, in particular, the use of interleukin-10 in the treatment of liver damage (e.g. fibrosis or cirrhosis) in a difficult-to-treat patient afflicted with chronic hepatitis C virus infection who has failed to respond to, or achieve a sustained virologic response to an anti-HCV therapy(e.g., interferon-&agr; in combination with ribavirin).
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: February 3, 2004
    Assignee: Schering Corporation
    Inventors: Paul C. Grint, David R. Nelson, Gary L. Davis
  • Combined use of interleukin 10 and methotrexate for immuno-modulatory therapy
    Patent number: 6544504
    Abstract: A combination of interleukin 10 and methotrexate is used to suppress autoimmune diseases including arthritis and psoriasis. It has been discovered that administration of a combination of interleukin 10 and methotrexate causes suppression of T cell proliferation. Concurrent use of both agents avoids the toxicity associated with higher doses of methotrexate.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: April 8, 2003
    Assignee: Schering Corporation
    Inventors: Paul C. Grint, Satwant Narula
  • Combination therapy for chronic hepatitis C infection
    Patent number: 6387365
    Abstract: There is disclosed a method for treating chronic hepatitis C infection in patients in need of such treating comprising administering an amount of alpha interferon in association with an amount of ribavirin effective to treat chronic hepatitis C infection with the absence or substantial reduction of side effects associated with administration of ribavirin and alpha interferon.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: May 14, 2002
    Assignee: Schering Corporation
    Inventors: Janice K. Albrecht, Paul C. Grint
  • Combination therapy for chronic hepatitis c infection
    Patent number: 6299872
    Abstract: There is disclosed a method for treating chronic hepatitis C infection in patients in need of such treating comprising administering an amount of alpha interferon in association with an amount of ribavirin effective to treat chronic hepatitis C infection with the absence or substantial reduction of side effects associated with administration of ribavirin and alpha interferon.
    Type: Grant
    Filed: May 2, 2000
    Date of Patent: October 9, 2001
    Assignee: Schering Corporation
    Inventors: Janice K. Albrecht, Paul C. Grint