Patents by Inventor Paul C. Guley

Paul C. Guley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of propranolol hydrochloride macrocrystals
    Patent number: 5095151
    Abstract: There is described a process for the preparation of high yields of propranolol hydrochloride having a particle size within the range of 420 to 1200 microns wherein the propanolol hydrochloride is recrystallized from, as a solvent, a mixture of n-propanol and heptane.The propranolol hydrochloride macrocrystals are useful themselves in capsule pharmaceutical dosage forms and when coated with a sustained release coating composition, are useful in the manufacture of sustained action capsule and tablet pharmaceutical dosage.
    Type: Grant
    Filed: May 21, 1985
    Date of Patent: March 10, 1992
    Assignee: American Home Products Corporation
    Inventors: Paul C. Guley, James S. Farina
  • Rapid releasing triamterene containing gelatin capsule dosage forms for once daily antihypertensive use
    Patent number: 4681765
    Abstract: A gelatin capsule dosage form containing triamterene, 2,4,7-triamino-6-phenylpteridine, which results in rapid dissolution of the active ingredient. The dosage form comprises the pharmaceutical binder methylcellulose in combination with low doses of a surfactant or a carbonate salt as disintegrants.
    Type: Grant
    Filed: September 13, 1984
    Date of Patent: July 21, 1987
    Assignee: American Home Products Corporation
    Inventor: Paul C. Guley
  • Sustained release pharmaceutical compositions
    Patent number: 4309406
    Abstract: Novel sustained release compositions comprising a core containing a drug, a seal coating surrounding the core and a sugar coating surround the seal coated core are disclosed.
    Type: Grant
    Filed: January 30, 1981
    Date of Patent: January 5, 1982
    Assignee: American Home Products Corporation
    Inventors: Paul C. Guley, Richard J. DeNeale, George Milosovich
  • Sustained release pharmaceutical compositions
    Patent number: 4309404
    Abstract: Novel sustained release compositions comprising a core containing a drug, a seal coating surrounding the core and a sugar coating surround the seal coated core are disclosed.
    Type: Grant
    Filed: January 30, 1981
    Date of Patent: January 5, 1982
    Assignee: American Home Products Corporation
    Inventors: Richard J. DeNeale, Paul C. Guley, George Milosovich
  • Sustained release pharmaceutical compositions
    Patent number: 4309405
    Abstract: Novel sustained release compositions comprising a core containing a drug, a seal coating surrounding the core and a sugar coating surround the seal coated core are disclosed.
    Type: Grant
    Filed: January 30, 1981
    Date of Patent: January 5, 1982
    Assignee: American Home Products Corporation
    Inventors: Paul C. Guley, Richard J. DeNeale, George Milosovich
  • Sustained release pharmaceutical compositions
    Patent number: 4248856
    Abstract: Novel sustained release compositions comprising a core containing a drug, a seal coating surrounding the core and a sugar coating surround the seal coated core are disclosed.
    Type: Grant
    Filed: July 10, 1979
    Date of Patent: February 3, 1981
    Assignee: American Home Products Corporation
    Inventors: Paul C. Guley, Richard J. DeNeale, George Milosovich
  • Sustained release pharmaceutical compositions
    Patent number: 4248857
    Abstract: Novel sustained release compositions comprising a core containing a drug, a seal coating surrounding the core and a sugar coating surrounding the seal coated core are disclosed.
    Type: Grant
    Filed: August 9, 1979
    Date of Patent: February 3, 1981
    Assignee: American Home Products Corporation
    Inventors: Richard J. DeNeale, Paul C. Guley, George Milosovich
  • Sustained release pharmaceutical compositions
    Patent number: 4248858
    Abstract: Novel sustained release compositions comprising a core containing a drug, a seal coating surrounding the core and a sugar coating surround the seal coated core are disclosed.
    Type: Grant
    Filed: August 9, 1979
    Date of Patent: February 3, 1981
    Assignee: American Home Products Corporation
    Inventors: Paul C. Guley, Richard J. DeNeale, George Milosovich