Patents by Inventor Paul Castella

Paul Castella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OCT-IVUS catheter for concurrent luminal imaging
    Patent number: 11350906
    Abstract: The invention relates to an apparatus for in vivo imaging. More specifically, the present invention relates to a catheter that incorporates an Optical Coherence Tomography (OCT) system and an Intravascular Ultrasound (“IVUS) system for concurrent imaging of luminal systems, such as imaging the vasculature system, including, without limitation, cardiac vasculature, peripheral vasculature and neural vasculature.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: June 7, 2022
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Paul Castella, Nathaniel J. Kemp, Thomas E. Milner, David G. Rosenbaum
  • Sandalwood oil and its uses related to oral mucositis
    Patent number: 10857191
    Abstract: Provided herein are methods of using therapeutically effective compositions of sandalwood oil to treat oral mucositis.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: December 8, 2020
    Assignee: SANTALIS PHARMACEUTICALS, INC.
    Inventors: Corey Levenson, Paul Castella, Ian Clements
  • OCT-IVUS CATHETER FOR CONCURRENT LUMINAL IMAGING
    Publication number: 20190209123
    Abstract: The invention relates to an apparatus for in vivo imaging. More specifically, the present invention relates to a catheter that incorporates an Optical Coherence Tomography (OCT) system and an Intravascular Ultrasound (“IVUS) system for concurrent imaging of luminal systems, such as imaging the vasculature system, including, without limitation, cardiac vasculature, peripheral vasculature and neural vasculature.
    Type: Application
    Filed: January 8, 2019
    Publication date: July 11, 2019
    Inventors: Paul CASTELLA, Nathaniel J. KEMP, Thomas E. MILNER, David G. ROSENBAUM
  • SANDALWOOD OIL AND ITS USES RELATED TO ORAL MUCOSITIS
    Publication number: 20190209630
    Abstract: Provided herein are methods of using therapeutically effective compositions of sandalwood oil to treat oral mucositis.
    Type: Application
    Filed: October 6, 2016
    Publication date: July 11, 2019
    Applicant: Santalis Pharmaceuticals, Inc.
    Inventors: Corey Levenson, Paul Castella, Ian Clements
  • Sandalwood oil and its uses related to clostridium infections
    Patent number: 10322154
    Abstract: Provided herein are methods of using therapeutically effective compositions of sandalwood oil to treat, prevent or reduce the recurrence of Clostridium infections.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: June 18, 2019
    Assignee: SANTALIS PHARMACEUTICALS, INC.
    Inventors: Ian Clements, Paul Castella, Corey Levenson
  • OCT-IVUS catheter for concurrent luminal imaging
    Patent number: 10219780
    Abstract: The invention relates to an apparatus for in vivo imaging. More specifically, the present invention relates to a catheter that incorporates an Optical Coherence Tomography (OCT) system and an Intravascular Ultrasound (“IVUS) system for concurrent imaging of luminal systems, such as imaging the vasculature system, including, without limitation, cardiac vasculature, peripheral vasculature and neural vasculature.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: March 5, 2019
    Assignee: Volcano Corporation
    Inventors: Paul Castella, Nathaniel J. Kemp, Thomas E. Milner, David G. Rosenbaum
  • SANDALWOOD OIL AND ITS USES
    Publication number: 20180042974
    Abstract: Provided herein are compositions of sandalwood oil and methods of making and using such compositions.
    Type: Application
    Filed: March 27, 2017
    Publication date: February 15, 2018
    Applicant: SANTALIS PHARMACEUTICALS, INC.
    Inventors: Ian Clements, Paul Castella, Corey Levenson
  • Stabilized cream formulations comprising sandalwood oil
    Patent number: 9861670
    Abstract: Provided herein are cream formulations comprising sandalwood oil, an antioxidant and a phosphate buffer. Also provided are methods of making and using the formulations. Further provided herein is a method of treating a skin disorder in a subject by administering to the subject a therapeutically effective amount of a cream formulation comprising sandalwood oil, an antioxidant and a phosphate buffer, wherein the subject has a skin disorder or is at risk of developing a skin disorder.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 9, 2018
    Assignee: SANTALIS HEALTHCARE CORPORATION
    Inventors: Ian Clements, Paul Castella, Corey Levenson
  • SANDALWOOD OIL AND ITS USES RELATED TO CLOSTRIDIUM INFECTIONS
    Publication number: 20170128509
    Abstract: Provided herein are methods of using therapeutically effective compositions of sandalwood oil to treat, prevent or reduce the recurrence of Clostridium infections.
    Type: Application
    Filed: January 13, 2017
    Publication date: May 11, 2017
    Applicant: Santalis Pharmaceuticals, Inc.
    Inventors: Ian Clements, Paul Castella, Corey Levenson
  • Sandalwood oil and its uses related to clostridium infections
    Patent number: 9579354
    Abstract: Provided herein are methods of using therapeutically effective compositions of sandalwood oil to treat, prevent or reduce the recurrence of Clostridium infections.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: February 28, 2017
    Assignee: Santalis Pharmaceuticals, Inc.
    Inventors: Ian Clements, Paul Castella, Corey Levenson
  • SANDALWOOD OIL AND ITS USES
    Publication number: 20160184374
    Abstract: Provided herein are compositions of sandalwood oil and methods of making and using such compositions.
    Type: Application
    Filed: July 29, 2015
    Publication date: June 30, 2016
    Inventors: Ian Clements, Paul Castella, Corey Levenson
  • Method and apparatus to identify vulnerable plaques with thermal wave imaging of heated nanoparticles
    Patent number: 9289131
    Abstract: Provided herein are systems, methods, and compositions for the thermal imaging of cells with nanoparticles.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: March 22, 2016
    Assignee: Board of Regents, the University of Texas System
    Inventors: Paul Castella, Jihoon Kim
  • STABILIZED CREAM FORMULATIONS COMPRISING SANDALWOOD OIL
    Publication number: 20160008415
    Abstract: Provided herein are cream formulations comprising sandalwood oil, an antioxidant and a phosphate buffer. Also provided are methods of making and using the formulations. Further provided herein is a method of treating a skin disorder in a subject by administering to the subject a therapeutically effective amount of a cream formulation comprising sandalwood oil, an antioxidant and a phosphate buffer, wherein the subject has a skin disorder or is at risk of developing a skin disorder.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 14, 2016
    Applicant: ViroXis Corporation
    Inventors: IAN CLEMENTS, Paul Castella, Corey Levenson
  • VENA CAVA FILTER CATHETER AND METHOD OF USE
    Publication number: 20150257867
    Abstract: A vena cava filter catheter includes a catheter having a lumen disposed therethrough and at least one strand of biocompatible wire. The at least one strand has a first state in which the at least one strand has an elongate geometry suitable for traversing the lumen of the catheter and a second state in which the at least one strand assumes a pre-set geometry in which the at least one strand assumes a tortuous configuration adapted to occupy a space approximating a luminal diameter of an inferior vena cava.
    Type: Application
    Filed: March 19, 2015
    Publication date: September 17, 2015
    Inventors: Paul Castella, Jeffrey N. Steinmetz
  • SANDALWOOD OIL AND ITS USES RELATED TO CLOSTRIDIUM INFECTIONS
    Publication number: 20150238551
    Abstract: Provided herein are methods of using therapeutically effective compositions of sandalwood oil to treat, prevent or reduce the recurrence of Clostridium infections.
    Type: Application
    Filed: January 23, 2013
    Publication date: August 27, 2015
    Inventors: Ian Clements, Paul Castella, Corey Levenson
  • ROTATING OPTICAL CATHETER TIP FOR OPTICAL COHERENCE TOMOGRAPHY
    Publication number: 20150230709
    Abstract: The present invention relates to a rotating catheter tip for optical coherence tomography based on the use of an optical fiber that does not rotate, that is enclosed in a catheter, which has a tip rotates under the influence of a fluid drive system to redirect light from the fiber to a surrounding vessel and the light reflected or backscattered from the vessel back to the optical fiber.
    Type: Application
    Filed: February 9, 2015
    Publication date: August 20, 2015
    Inventors: Thomas E. Milner, Marc D. Feldman, Jung-Hwan Oh, Shaochen Chen, Paul Castella
  • Vena cava filter catheter and method of use
    Patent number: 8992504
    Abstract: A vena cava filter catheter includes a catheter having a lumen disposed therethrough and at least one strand of biocompatible wire. The at least one strand has a first state in which the at least one strand has an elongate geometry suitable for traversing the lumen of the catheter and a second state in which the at least one strand assumes a pre-set geometry in which the at least one strand assumes a tortuous configuration adapted to occupy a space approximating a luminal diameter of an inferior vena cava.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: March 31, 2015
    Assignee: BiO2 Medical, Inc.
    Inventors: Paul Castella, Jeffrey N. Steinmetz
  • Rotating optical catheter tip for optical coherence tomography
    Patent number: 8989849
    Abstract: The present invention relates to a rotating catheter tip for optical coherence tomography based on the use of an optical fiber that does not rotate, that is enclosed in a catheter, which has a tip rotates under the influence of a fluid drive system to redirect light from the fiber to a surrounding vessel and the light reflected or backscattered from the vessel back to the optical fiber.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: March 24, 2015
    Assignee: Board of Regents, the University of Texas System
    Inventors: Thomas E. Milner, Marc D. Feldman, Jung-Hwan Oh, Shaochen Chen, Paul Castella
  • Vena cava filter catheter and method
    Patent number: 8771226
    Abstract: A vena cava filter catheter includes a catheter having a lumen disposed therethrough and at least one strand of biocompatible wire. The at least one strand has a first state in which the at least one strand has an elongate geometry suitable for traversing the lumen of the catheter and a second state in which the at least one strand assumes a pre-set geometry in which the at least one strand assumes a tortuous configuration adapted to occupy a space approximating a luminal diameter of an inferior vena cava.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: July 8, 2014
    Assignee: Bio2Medical, Inc.
    Inventors: Paul Castella, Jeffrey N. Steinmetz
  • SANDALWOOD OIL AND ITS USES RELATED TO SKIN DISORDERS
    Publication number: 20140154342
    Abstract: Provided herein are compositions of sandalwood heartwood oil and methods of making and using such compositions.
    Type: Application
    Filed: July 27, 2012
    Publication date: June 5, 2014
    Applicant: SANTALIS PHARMACEUTICALS INC.
    Inventors: Ian Clements, Paul Castella, Corey Levenson