Abstract: A complex comprises a CRBN having a europium-anti-his antibody on the N-terminus of the CRBN, and a Cy5-conjugated small molecule, wherein the Cy5-conjugated small molecule binds the CRBN, and uses thereof for identifying therapeutic compounds.

Abstract: There is provided a mounting bracket for attaching a light fixture to a light pole, with the light pole having an external surface, an internal surface defining an internal cavity, and a pair of apertures extending from the external surface to the internal surface. The mounting bracket includes an internal support sized and structured to be insertable within the internal cavity of the light pole. The internal support includes a housing and a pair of fasteners moveable relative to the housing and alignable with respective ones of the pair of apertures. An external support is sized and structured to be positionable adjacent the external surface of the light pole, the external support having a pair of slots formed therein and alignable with respective ones of the pair of fasteners. A mount body is slidably engageable with the external support and is pivotally connectable to the light fixture.

Abstract: Optically and thermally efficient light bars and light fixtures which are uniquely configured to provide light fidelity (Li-Fi) wireless communications. In a first embodiment, an LED light bar is outfitted with components adapted to provide Li-Fi wireless communications, while further being configured to provide superior heat dissipation characteristics and adapted for retrofit applications in substitution for any one of a variety of linear fluorescent light fixtures. In a second embodiment, an LED light fixture, potentially suitable for use in high bay or ceiling applications, is outfitted with components adapted to provide Li-Fi wireless communications, while further being configured to provide superior heat dissipation and light emission/distribution characteristics and also adapted for retrofit applications in substitution for any one of a variety of conventional linear fluorescent and non-LED light fixtures.

Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1.

Abstract: A leak test apparatus that includes a test chamber, a pressure transducer, a vacuum source, and a vapor trap. The test chamber may be configured to receive a test part and the pressure transducer may be coupled in fluidic communication to the test chamber. The vacuum source and the vapor trap may be coupled in fluidic communication to the test chamber. The vacuum source may be configured to draw a vacuum on the test chamber and the vapor trap may be configured to mitigate vapor off-gassing. A method for leak testing includes positioning a test part in a test chamber, evacuating the test chamber to a vacuum pressure with a vacuum source, mitigating vapor off-gassing with a vapor trap, and detecting a pressure rise in the test chamber.

Abstract: A method for integrating employee training management with on-the-job employee performance evaluation, whereby one or more specified training courses are completed by one or more employees. One or more observations are automatically assigned to the one or more employees. The assignments are completed by one or more supervisors. In a system for performing same, a processor is operatively coupled to a memory device configured for storing program code which, when executed by the processor, causes the processor to perform steps of receiving notifications when one or more specified training courses is completed by one or more employees; automatically assigning one or more observations to the one or more employees; and receiving notifications when the assignments are completed by one or more supervisors.

Abstract: Methods and apparatus are disclosed for updating displayed representations of data. The methods and apparatus include displaying an input component to receive query criteria based on one or more data fields displayed in charts, receiving the query criteria in a single request from the input component, updating queries associated with chart displays to include the query criteria, executing the queries, and updating the charts based upon results of executing the queries. The query criteria may include a data value associated with the data field. The query criteria may include a condition based upon the data fields, and can be added to conditional expressions in the queries. Updating the charts may include displaying graphical chart elements that are proportional in size to values of the data fields of the results of executing the plurality of queries.

Abstract: A heat dissipating LED light bar which may be used as part of a complete retrofit system for a variety of linear fluorescent light fixtures. The LED light bar comprises an elongate channel member which is preferably fabricated from extruded aluminum. In addition to the channel member, the LED light bar comprises a high-efficacy set of LEDs, which are preferably provided in the form of an elongate LED printed circuit board (PCB) or strip mechanically bonded to the channel member. The channel member is outfitted with fins and other surface features uniquely configured to provide superior heat dissipation, thus allowing the channel member to effectively function as a heat sink for the LED strip cooperatively engaged thereto. Further, the channel member is configured to define an air flow cavity under the LED strip as allows for the effective dissipation of heat during operation of the LED light bar.

Abstract: A complex comprises a CRBN having a europium-anti-his antibody on the N-terminus of the CRBN, and a Cy5-conjugated small molecule, wherein the Cy5-conjugated small molecule binds the CRBN, and uses thereof for identifying therapeutic compounds.

Abstract: A heat dissipating and optically efficient LED high bay light bar which may be used as part of a complete retrofit system for a variety of linear fluorescent light fixtures. The LED high bay light bar comprises an elongate channel member which is preferably fabricated from extruded aluminum. In addition to the channel member, the LED high bay light bar comprises a high-efficacy set of LEDs, which are preferably provided in the form of an elongate LED printed circuit board (PCB) or strip mechanically bonded to the channel member. The channel member is outfitted with fins and other surface features uniquely configured to provide superior heat dissipation, thus allowing the channel member to effectively function as a heat sink for the LED strip cooperatively engaged thereto. The channel member is configured to define an air flow cavity under the LED strip as allows for the effective dissipation of heat during operation of the LED light bar.

Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1.

Abstract: A heat dissipating and optically efficient LED high bay light bar which may be used as part of a complete retrofit system for a variety of linear fluorescent light fixtures. The LED high bay light bar comprises an elongate channel member which is preferably fabricated from extruded aluminum. In addition to the channel member, the LED high bay light bar comprises a high-efficacy set of LEDs, which are preferably provided in the form of an elongate LED printed circuit board (PCB) or strip mechanically bonded to the channel member. The channel member is outfitted with fins and other surface features uniquely configured to provide superior heat dissipation, thus allowing the channel member to effectively function as a heat sink for the LED strip cooperatively engaged thereto. The channel member is configured to define an air flow cavity under the LED strip as allows for the effective dissipation of heat during operation of the LED light bar.

Abstract: A heat dissipating LED light bar which may be used as part of a complete retrofit system for a variety of linear fluorescent light fixtures. The LED light bar comprises an elongate channel member which is preferably fabricated from extruded aluminum. In addition to the channel member, the LED light bar comprises a high-efficacy set of LEDs, which are preferably provided in the form of an elongate LED printed circuit board (PCB) or strip mechanically bonded to the channel member. The channel member is outfitted with fins and other surface features uniquely configured to provide superior heat dissipation, thus allowing the channel member to effectively function as a heat sink for the LED strip cooperatively engaged thereto. Further, the channel member is configured to define an air flow cavity under the LED strip as allows for the effective dissipation of heat during operation of the LED light bar.

Abstract: A method for integrating employee training management with on-the-job employee performance evaluation, whereby one or more specified training courses are completed by one or more employees. One or more observations are automatically assigned to the one or more employees. The assignments are completed by one or more supervisors. In a system for performing same, a processor is operatively coupled to a memory device configured for storing program code which, when executed by the processor, causes the processor to perform steps of receiving notifications when one or more specified training courses is completed by one or more employees; automatically assigning one or more observations to the one or more employees; and receiving notifications when the assignments are completed by one or more supervisors.

Abstract: The present invention describes a flight recorder for an aircraft with an instrument display panel for displaying aircraft status data to a pilot. The flight recorder comprises one or more sensors that monitor one or more flight conditions of the aircraft, a camera unit for providing image data and a data storage unit for storing the aircraft status data and image data from the camera. The flight recorder additionally comprises a control unit for monitoring the flight condition data supplied by the sensors.

Abstract: Methods and apparatus are disclosed for updating displayed representations of data. The methods and apparatus include displaying an input component to receive query criteria based on one or more data fields displayed in charts, receiving the query criteria in a single request from the input component, updating queries associated with chart displays to include the query criteria, executing the queries, and updating the charts based upon results of executing the queries. The query criteria may include a data value associated with the data field. The query criteria may include a condition based upon the data fields, and can be added to conditional expressions in the queries. Updating the charts may include displaying graphical chart elements that are proportional in size to values of the data fields of the results of executing the plurality of queries.

Abstract: A musicians hearing device by which a musician may easily hear in a more clear and obvious way what is coming out of their horn or musical instrument. The acoustic personal monitor samples the tones being created inside the instrument and channels the frequency out of the instrument, extending to the musician and through a sealed ear bud into their ear or ears.

Abstract: Leak testing using a testing chamber into which a test part may be configured for testing. The test part defines a leak test boundary to be tested. Tracer gas is introduced into a first volume on one side of the leak test boundary. A vacuum (e.g., a rough vacuum) may be introduced into a second volume on the opposite side of the leak test boundary. A tracer gas permeable membrane is placed in situ within the second volume, or at least in gaseous communication with the second volume perhaps within or rigidly attached to the wall of the chamber. During testing, if some of the tracer gas introduced into the first volume were to leak through the leak test boundary defined by the test part into the second volume, at least some of that tracer gas may pass the tracer gas permeable membrane for subsequent detection.

Abstract: In a fipple flute, an instrument body includes an outer surface defining an interior resonating cavity. An airway extends from the outer surface into the resonating cavity and includes an adaptor which joins a brass instrument mouthpiece with a fipple flute. The tone produced from the brass instrument mouthpiece along with the separate tone generated by the fipple whistle allows the player the ability to create new sounds and harmonies.

Abstract: In a fipple flute, an instrument body includes an outer surface defining an interior resonating cavity. An airway extends from the outer surface into the resonating cavity and includes an adaptor which joins a brass instrument mouthpiece with a fipple flute.