Abstract: A sole structure for an article of footwear defines a footbed and includes a chassis having a lower cushioning element including an upper side and a bottom side disposed on an opposite side from the upper side, the lower cushioning element including one or more apertures extending from the upper side to the bottom side. A bladder is disposed adjacent to the upper side of the lower cushioning element and an outsole is disposed adjacent to the bottom side of the lower cushioning element and includes one or more protrusions each extending through a respective one of the one or more apertures and engaging the bladder.

Abstract: The invention relates to a construct comprising a compound targeting areas in the brain involved in the regulation of body weight and an allosteric ligand to a receptor located in the blood-brain barrier (BBB). The invention also relates to compositions and uses of such construct, for example in the prevention or treatment of overweight and obesity. Preferred compounds for regulation of body weight include GLP-1 receptor agonists (GLP-1RA), and preferred receptors located in the BBB include the transferrin receptor (TfR). Exemplary fusions and conjugates of GLP-1 RA's and anti TfR-Fab's exhibit an increased binding to brain regions expressing the GLP-1 receptor as compared to fusions or conjugates with inactive control Fab's, in particular in brain areas protected by the BBB. In vivo mice studies confirm increased reduction in food intake as well as weight loss for the active construct compared to the inactive one.

Abstract: A furniture panel and a furniture assembly which incorporates such a panel. The panel is formed from at least two structural components including a first structural component being an edge structure and a second or subsequent structural component(s) selected from one or more cover sheet(s) and one or more edge structure(s). At least one internal fixing element is also provided to engage together at least two of said structural components, with the internal fixing element or elements being at least partially enclosed within a housing defined by the engagement of said structural components. The housing defined at least partially conceals the internal fixing element from view.

Abstract: The invention relates to a construct comprising a compound targeting areas in the brain involved in the regulation of body weight and an allosteric ligand to a receptor located in the blood-brain barrier (BBB). The invention also relates to compositions and uses of such construct, for example in the prevention or treatment of overweight and obesity. Preferred compounds for regulation of body weight include GLP-1 receptor agonists (GLP-1RA), and preferred receptors located in the BBB include the transferrin receptor (TfR). Exemplary fusions and conjugates of GLP-1 RA's and anti TfR-Fab's exhibit an increased binding to brain regions expressing the GLP-1 receptor as compared to fusions or conjugates with inactive control Fab's, in particular in brain areas protected by the BBB. In vivo mice studies confirm increased reduction in food intake as well as weight loss for the active construct compared to the inactive one.

Abstract: A method of operating a computing device includes receiving occupancy data for an operating environment of a mobile robot based on localization data detected by at least one localization sensor of the mobile robot responsive to navigation thereof in the operating environment, and receiving signal coverage data for the operating environment based on wireless communication signals acquired by at least one wireless receiver of the mobile robot responsive to navigation thereof in the operating environment. The wireless communication signals are transmitted by at least one electronic device that is local to the operating environment. The method further includes generating a map indicating coverage patterns of the wireless communication signals at respective locations in the operating environment by correlating the occupancy data and the signal coverage data. Related methods, mobile robots, and user terminals are also discussed.

Abstract: A method of operating a computing device includes receiving occupancy data for an operating environment of a mobile robot based on localization data detected by at least one localization sensor of the mobile robot responsive to navigation thereof in the operating environment, and receiving signal coverage data for the operating environment based on wireless communication signals acquired by at least one wireless receiver of the mobile robot responsive to navigation thereof in the operating environment. The wireless communication signals are transmitted by at least one electronic device that is local to the operating environment. The method further includes generating a map indicating coverage patterns of the wireless communication signals at respective locations in the operating environment by correlating the occupancy data and the signal coverage data. Related methods, mobile robots, and user terminals are also discussed.

Abstract: A switch and methods of assembling a switch. The switch may include a housing; a first terminal electrically coupled to a power source; a second terminal electrically coupled to a load; a contact having a first contact end and a second contact end, the contact being operable to be in a closed position, in which the first contact end engages the first terminal and the second contact end engages the second terminal such that the contact electrically connects the first terminal to the second terminal, and an open position, in which the contact does not electrically connect the first terminal and the second terminal; and a biasing member configured to bias the contact towards the first terminal and the second terminal, the biasing member being operable to apply a first biasing force proximate the first contact end and a second biasing force proximate the second connect end.

Abstract: A driver circuit for an LED display for switching a light-emitting diode (LED) between a non-luminous state and a luminous state for producing light for a display, the driver circuit comprising an LED, a drive current controller (10) arranged to selectively open and close a drive current flow path (8) through the LED (2) thereby selectively to switch the LED between a non-luminous state and a luminous state, a charge injector unit (13) for inputting charge into the LED to store said charge within the LED via the junction capacitance (3) thereof, a control unit (12) arranged to control the charge injector unit to input said charge into the LED concurrently with the opening of the drive current flow path.

Abstract: A method of operating a computing device includes receiving occupancy data for an operating environment of a mobile robot based on localization data detected by at least one localization sensor of the mobile robot responsive to navigation thereof in the operating environment, and receiving signal coverage data for the operating environment based on wireless communication signals acquired by at least one wireless receiver of the mobile robot responsive to navigation thereof in the operating environment. The wireless communication signals are transmitted by at least one electronic device that is local to the operating environment. The method further includes generating a map indicating coverage patterns of the wireless communication signals at respective locations in the operating environment by correlating the occupancy data and the signal coverage data. Related methods, mobile robots, and user terminals are also discussed.

Abstract: An approach for providing location sharing via simulation is disclosed. A location sharing platform determines at least one location point associated with at least one device and at least one algorithm for determining at least one predicted route of the at least one device based, at least in part, on the at least one location point. The location sharing platform then causes, at least in part, a transmission of the at least one location point and the at least one algorithm to at least one other device for generating location tracking information.

Abstract: A driver circuit for an LED display for switching a light-emitting diode (LED) between a non-luminous state and a luminous state for producing light for a display, the driver circuit comprising an LED, a drive current controller (10) arranged to selectively open and close a drive current flow path (8) through the LED (2) thereby selectively to switch the LED between a non-luminous state and a luminous state, a charge injector unit (13) for inputting charge into the LED to store said charge within the LED via the junction capacitance (3) thereof, a control unit (12) arranged to control the charge injector unit to input said charge into the LED concurrently with the opening of the drive current flow path.

Abstract: A switch and methods of assembling a switch. The switch may include a housing; a first terminal electrically coupled to a power source; a second terminal electrically coupled to a load; a contact having a first contact end and a second contact end, the contact being operable to be in a closed position, in which the first contact end engages the first terminal and the second contact end engages the second terminal such that the contact electrically connects the first terminal to the second terminal, and an open position, in which the contact does not electrically connect the first terminal and the second terminal; and a biasing member configured to bias the contact towards the first terminal and the second terminal, the biasing member being operable to apply a first biasing force proximate the first contact end and a second biasing force proximate the second connect end.

Abstract: A device may process images (e.g. sort, group, file, e-mail, etc.) using various filters. The filters may relate to non-image data in the image files to be processed. The filters may include time and location filters.

Abstract: An approach for providing location sharing via simulation is disclosed. A location sharing platform determines at least one location point associated with at least one device and at least one algorithm for determining at least one predicted route of the at least one device based, at least in part, on the at least one location point. The location sharing platform then causes, at least in part, a transmission of the at least one location point and the at least one algorithm to at least one other device for generating location tracking information.

Abstract: An approach for providing location sharing via simulation is disclosed. A location sharing platform determines at least one location point associated with at least one device and at least one algorithm for determining at least one predicted route of the at least one device based, at least in part, on the at least one location point. The location sharing platform then causes, at least in part, a transmission of the at least one location point and the at least one algorithm to at least one other device for generating location tracking information.

Abstract: A method, apparatus and computer program product are provided for accessing user data and determining one or more nearby individuals at a first time, receiving one or more device identifiers transmitted from other computing devices, and mapping the one or more device identifiers with the one or more nearby individuals. The method, apparatus, and computer program product may also be configured for determining whether each of one or more device identifiers are mapped to a specific individual, and if not, access stored data from previous occurrences in order to map the device identifiers to specific individuals.

Abstract: A computing device is provided that includes a plurality of user-interactive mechanisms. The computing device may also include a universal communication port that is capable of receiving a connection from a device that belongs to any one of a plurality of device classes or types. The device may be equipped or configured with logic. The logic may configure or otherwise enable an operative state of user-interface mechanisms on the device. Additionally, the logic may (i) detect a connected device that connects to the universal communication port, and (ii) determine a set of functionality that the connected device is capable of performing when connected to the universal communication port. The logic may perform, or cause performance, of operations that are for use with or by the connected device.

Abstract: A method, apparatus and computer program product are provided for accessing user data and determining one or more nearby individuals at a first time, receiving one or more device identifiers transmitted from other computing devices, and mapping the one or more device identifiers with the one or more nearby individuals. The method, apparatus, and computer program product may also be configured for determining whether each of one or more device identifiers are mapped to a specific individual, and if not, access stored data from previous occurrences in order to map the device identifiers to specific individuals.

Abstract: The invention relates to composition and related therapeutic methods including at least one antihyperthyroid drug formulated for transdermal administration. Because the formulation is formulated for transdermal administration, the formulation is easier to administer than existing formulations which are administered orally to animals. Issues surrounding transdermal administration versus oral administration have also been resolved allowing the agent to remain stable during storage and retain a high level of efficacy.

Abstract: A wind turbine assembly comprising an inflatable rotor assembly.