Abstract: A device for insertion in a receptacle for pressurisation, evacuation, and/or acceleration by centrifugation, comprising: a vessel with side walls and a base; wherein the side walls of the vessel comprise at least one portal; wherein the portal is partially or wholly covered by a semipermeable membrane; wherein the semipermeable membrane is located vertically with respect to the receptacle for centrifugation; and wherein the filtering surface of the semipermeable membrane faces externally with respect to the interior of the vessel. Also provided are methods for processing liquids or suspensions utilising such devices and methods for manufacturing such devices.