Patents by Inventor Paul Chen

Paul Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Exercise apparatus adjustable for sidewise moving
    Publication number: 20130116094
    Abstract: An exercise apparatus includes a base having a carrier, two brackets attached to the carrier and adjustable relative to carrier between a forwardly directed position and a sidewise directed position, and two foot supports pivotally attached to the brackets and to be pivoted and swung forwardly and rearwardly relative to the brackets and the carrier when the brackets are attached to the carrier at the forwardly directed position, and the foot supports are allowed to be pivoted and swung sidewise relative to the brackets and the carrier when the brackets are attached to the carrier at the sidewise directed position.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 9, 2013
    Inventor: Paul Chen
  • Balancing exerciser
    Publication number: 20130116100
    Abstract: A balancing exerciser includes an immovable base having a socket opening for pivotally engaging with a universal joint device which has a shank, a plate is located above the base for supporting a user and includes a hole for engaging with the shank, and a knob engaged with the shank of the universal joint device and engaged with the plate for securing the plate to the shank of the universal joint device and for attempting to maintain the plate in a horizontal position or status and for allowing the user to conduct the balancing exercises or operations. The shank of the universal joint device is selected from a threaded shank for engaging with the threaded hole of the plate and for adjusting the plate toward and away from the base.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 9, 2013
    Inventor: Paul Chen
  • Method of Supplementing Culture Media to Prevent Undesirable Amino Acid Substitutions
    Publication number: 20130096283
    Abstract: The present invention relates to methods of reducing substitution of amino acids during the production of polypeptides of interest in mammalian cells. By varying the concentration of amino acids in the culture medium, heterogeneity of the polypeptide's amino acid sequence is decreased, leading to higher yields of functional protein.
    Type: Application
    Filed: November 24, 2009
    Publication date: April 18, 2013
    Applicant: Biogen Idec MA inc.
    Inventors: Anurag Khetan, Yao-ming Huang, Jana Dolnikova, Nels Pederson, Helena Yusuf-Makagiansar, Paul Chen, Thomas Ryll
  • Skiing simulating exercise machine
    Publication number: 20130095982
    Abstract: A skiing simulating exercise machine includes a supporting base for supporting a user, a pair of retractable couplers attached to the supporting base, and a pair of handle devices coupled to the retractable couplers for being grasped by the user and for simulating a skiing operation. The supporting base includes a beam for attaching the retractable couplers, the retractable couplers each include a rod slidably engaged in a housing, and a spring biasing member coupled between the rod and the housing for retracting the rod into the housing. The retractable couplers each include a wheel attached to the rod for allowing the rod to be smoothly moved into and out of the housing.
    Type: Application
    Filed: October 12, 2011
    Publication date: April 18, 2013
    Inventor: Paul Chen
  • Rotational display system
    Patent number: 8411108
    Abstract: The present invention provides a system which integrates unique lighting technologies, switching systems, mounting systems, information delivery systems and power supply systems within a support such as vehicular wheel to provide an advanced, high quality visual display apparatus in various surfaces of rotation. A displayed image may be three dimensional. These technologies, and their many unique applications, provide for a novel and useful series of video display devices that are small, lightweight, efficient and can have the capability of producing a clear, bright, high definition image that is equivalent to that of a modern day TV or high quality computer monitor.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: April 2, 2013
    Assignee: Lightning Wheels, LLC
    Inventors: Mark D. Gilbert, Paul Chen, Lawrence Moens
  • Skiing simulating exercise machine
    Publication number: 20130045841
    Abstract: A skiing simulating exercise machine includes a pair of handles attached to a base support for supporting an upper portion of a user, a cushioning member disposed on the base support, and a platform mounted on the cushioning member for supporting the user thereon and for simulating a skiing operation, the cushioning member includes a chamber for forming a tubular element and for increasing a resilience of the cushioning member, the cushioning member includes an outer peripheral recess for increasing a resilience of the cushioning member and for allowing the cushioning member to be suitably deformed or twisted or squeezed or depressed or compressed by the user.
    Type: Application
    Filed: August 18, 2011
    Publication date: February 21, 2013
    Inventor: Paul Chen
  • Functionalized halogenated polymers for microencapsulation
    Patent number: 8361620
    Abstract: The present invention is directed to a novel reactive protective colloid system suitable for stabilizing an electrophoretic display in which a halogenated solvent, particularly a fluorinated, more particularly a perfluorinated, solvent, or a mixture thereof, is used as the dielectric solvent.
    Type: Grant
    Filed: February 13, 2006
    Date of Patent: January 29, 2013
    Assignee: SiPix Imaging, Inc.
    Inventors: Hongmei Zang, Huiyong Paul Chen, Mahmoud-Zohdi Armoush, Denis Leroux, Rongchi Yu, Rong-Chang Liang
  • Dumbbell having rolling or shaking device
    Patent number: 8246525
    Abstract: A barbell or dumbbell or exercise device includes a handle having two end portions, a weight member attached to either of the end portions of the handle and having a ball guiding raceway for engaging with a rolling device which is movable along the ball guiding raceway of the weight member for generating a vibration to the weight member and the handle, the weight member includes a housing attached onto the weight member and engaged with the rolling device for retaining the rolling device in the weight member, for example, the housing includes a chamber for receiving the weight member and includes a peripheral flange extended radially and inwardly into the chamber and secured to the weight member.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: August 21, 2012
    Inventor: Paul Chen
  • Compounds as kinase inhibitors
    Patent number: 8211911
    Abstract: The present invention relates to compounds of Formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: July 3, 2012
    Inventor: Guoqing Paul Chen
  • SPIRO SUBSTITUTED COMPOUNDS AS ANGIOGENESIS INHIBITORS
    Publication number: 20120165371
    Abstract: The present invention relates to spiro (tetracarbon) substituted compound of Formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
    Type: Application
    Filed: March 5, 2012
    Publication date: June 28, 2012
    Applicant: ADVENCHEN LABORATORIES, LLC
    Inventor: Guoqing Paul CHEN
  • Compounds As c-Met Kinase Inhibitors
    Publication number: 20120123126
    Abstract: The present invention relates to compounds, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with the inhibition of the protein tyrosine kinase activity of growth factor receptors such as c-Met, thereby making them useful as anticancer agents, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
    Type: Application
    Filed: September 8, 2011
    Publication date: May 17, 2012
    Inventor: Guoqing Paul Chen
  • Dumbbell having rolling or shaking device
    Publication number: 20120115690
    Abstract: A barbell or dumbbell or exercise device includes a handle having two end portions, a weight member attached to either of the end portions of the handle and having a ball guiding raceway for engaging with a rolling device which is movable along the ball guiding raceway of the weight member for generating a vibration to the weight member and the handle, the weight member includes a housing attached onto the weight member and engaged with the rolling device for retaining the rolling device in the weight member, for example, the housing includes a chamber for receiving the weight member and includes a peripheral flange extended radially and inwardly into the chamber and secured to the weight member.
    Type: Application
    Filed: November 8, 2010
    Publication date: May 10, 2012
    Inventor: Paul Chen
  • Swinging and climbing exercise apparatus
    Publication number: 20120115694
    Abstract: An exercise apparatus includes a base frame having a rear track and a front column, a handle attached to the column for supporting a user, a lever includes an upper portion pivotally attached to an upper portion of the column and a lower portion movably engaged with the track of the base frame for guiding the lever to rotate relative to the column, and a support device is slidably and movably engaged with the lever for moving up and down along the lever and for allowing the user to conduct either the swinging exercise or the climbing or elevating exercise or to exercise or train either his upper muscle groups or his abdominal muscle groups with a single exercise machine.
    Type: Application
    Filed: November 8, 2010
    Publication date: May 10, 2012
    Inventor: Paul Chen
  • Spiro substituted compounds as angiogenesis inhibitors
    Patent number: 8163923
    Abstract: The present invention relates to spiro (tetracarbon) substituted compound of Formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
    Type: Grant
    Filed: February 23, 2008
    Date of Patent: April 24, 2012
    Assignee: Advenchen Laboratories, LLC
    Inventor: Guoqing Paul Chen
  • Spiro substituted compounds as angiogenesis inhibitors
    Patent number: 8148532
    Abstract: The present invention relates to compound of Formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
    Type: Grant
    Filed: February 23, 2008
    Date of Patent: April 3, 2012
    Inventor: Guoqing Paul Chen
  • TEMPERATURE DISTRIBUTION IMPROVEMENT IN REFRIGERATED CONTAINER
    Publication number: 20110283719
    Abstract: The fan of a refrigeration machine operatively connected to a container box is operated in one direction during normal operation and is periodically operated in the opposite direction in order to reverse the direction of airflow to and from the container box so as to thereby promote a more uniform temperature distribution within the container box. A door is automatically closed when operating in the reverse direction so as to accelerate the airflow speed into the container box.
    Type: Application
    Filed: February 4, 2010
    Publication date: November 24, 2011
    Applicant: CARRIER CORPORATION
    Inventors: Yu H. Chen, Paul Chen
  • Spiro Compounds And Methods Of Use
    Publication number: 20110237794
    Abstract: The present invention relates to spiro compounds of formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states such as cancers associated with protein tyrosine kinases, especially epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF), to their method of use as medicaments and to their method of use in the manufacture of medicaments for use in the production of inhibition of tyrosine kinase reducing effects in warm-blooded animals such as humans.
    Type: Application
    Filed: June 1, 2011
    Publication date: September 29, 2011
    Inventor: GUOQING PAUL CHEN
  • Visual Simulation of Touch Pressure
    Publication number: 20110227877
    Abstract: The simulation of touch pressure on a touch-sensitive display is disclosed. In one disclosed embodiment, a touch pressure is simulated on a touch-sensitive display by detecting inputs corresponding to each of an untouched display and two or more measures of touch pressure, and displaying images on the display corresponding to the untouched display and each measure of touch pressure. In this manner, a user may be provided with a richer visual response to a touch-sensitive display input.
    Type: Application
    Filed: May 27, 2011
    Publication date: September 22, 2011
    Applicant: MICROSOFT CORPORATION
    Inventor: Paul Chen
  • Spiro compounds and methods of use
    Patent number: 7977346
    Abstract: The present invention relates to spiro compounds of formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states such as cancers associated with protein tyrosine kinases, especially epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF), to their method of use as medicaments and to their method of use in the manufacture of medicaments for use in the production of inhibition of tyrosine kinase reducing effects in warm-blooded animals such as humans.
    Type: Grant
    Filed: December 30, 2006
    Date of Patent: July 12, 2011
    Inventor: Guoqing Paul Chen
  • Non-opaque light cover for a light fixture
    Patent number: D671259
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: November 20, 2012
    Assignee: Honesty Lighting, Inc.
    Inventor: Paul Chen