Patents by Inventor Paul Christopher Fritch

Paul Christopher Fritch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of ion channels
    Patent number: 8741934
    Abstract: The invention is directed to compounds of Formula I in which: R5, R6, B and Z are defined supra.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: June 3, 2014
    Assignees: Pfizer Limited, Icagen, Inc.
    Inventors: Brian Edward Marron, Paul Christopher Fritch, Christopher John Markworth, Andrew Thomas Maynard, Nigel Alan Swain
  • Inhibitors of Ion Channels
    Publication number: 20130072471
    Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.
    Type: Application
    Filed: November 15, 2012
    Publication date: March 21, 2013
    Inventors: Brian Edward Marron, Paul Christopher Fritch, Christopher John Markworth, Andrew Thomas Maynard, Nigel Alan Swain
  • Heterocyclic sulfonamides as inhibitors of ion channels
    Patent number: 8357711
    Abstract: The invention is directed to compounds of the formula in which R5, R6 B and Z are defined supra.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: January 22, 2013
    Assignees: Pfizer Limited, Icagen, Inc.
    Inventors: Brian Edward Marron, Paul Christopher Fritch, Christopher John Markworth, Andrew Thomas Maynard, Nigel Alan Swain
  • Calcium channel antagonists
    Patent number: 8034954
    Abstract: The present invention provides novel calcium channel antagonists, and methods of treating disease sates using the novel antagonists.
    Type: Grant
    Filed: December 20, 2006
    Date of Patent: October 11, 2011
    Assignee: Icagen, Inc.
    Inventors: Gregory J. Pacofsky, Mark J. Suto, Paul Christopher Fritch
  • INHIBITORS OF ION CHANNELS
    Publication number: 20090143358
    Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.
    Type: Application
    Filed: March 20, 2008
    Publication date: June 4, 2009
    Applicants: ICAgen, Inc., Pfizer Limited
    Inventors: Brian Edward Marron, Paul Christopher Fritch, Christopher John Markworth, Andrew Thomas Maynard, Nigel Alan Swain
  • Pyridine-substituted benzanilides as potassium ion channel openers
    Patent number: 6495550
    Abstract: The present invention provides a genus of pyridine-substituted benzanilides that are useful as openers of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: December 17, 2002
    Assignee: ICAgen, Inc.
    Inventors: Grant McNaughton-Smith, Paul Christopher Fritch, George Salvatore Amato
  • Pyridine-substituted benzanilides as potassium ion channel openers
    Publication number: 20010049444
    Abstract: The present invention provides a genus of pyridine-substituted benzanilides that are useful as openers of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.
    Type: Application
    Filed: February 2, 2001
    Publication date: December 6, 2001
    Inventors: Grant McNaughton-Smith, Paul Christopher Fritch, George Salvatore Amato