Patents by Inventor Paul Cockwell

Paul Cockwell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating a subject suffering from end stage renal disease against cardiovascular disease
    Patent number: 8657775
    Abstract: The present invention relates to high cut-off hemodialysis membranes for the treatment of chronic hemodialysis (CHD) patients, with the potential to improve long-term survival of these patients by reducing the risk of cardiovascular disease, through down-regulation of monocyte activation in the blood. Monocytes are the major circulating blood cells involved in the progression of cardiovascular disease. High cut-off hemodialysis in chronic dialysis patients results in a sustained decrease in expression of monocyte cell-surface proteins that direct the movement of these cells from the blood to the walls of blood vessels, where they promote the progression of arterial disease (atherosclerosis) that leads to cardiovascular disease (CVD); heart disease, strokes and peripheral vascular disease.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: February 25, 2014
    Assignee: Gambro Lundis AB
    Inventors: Colin Hutchison, Paul Cockwell, Hermann Göhl, Bernd Krause, Markus Storr
  • High cut-off hemodialysis membranes for the treatment of chronic hemodialysis patients
    Publication number: 20100084339
    Abstract: The present invention relates to high cut-off hemodialysis membranes for the treatment of chronic hemodialysis (CHD) patients, with the potential to improve long-term survival of these patients by reducing the risk of cardiovascular disease, through down-regulation of monocyte activation in the blood. Monocytes are the major circulating blood cells involved in the progression of cardiovascular disease. High cut-off hemodialysis in chronic dialysis patients results in a sustained decrease in expression of monocyte cell-surface proteins that direct the movement of these cells from the blood to the walls of blood vessels, where they promote the progression of arterial disease (atherosclerosis) that leads to cardiovascular disease (CVD); heart disease, strokes and peripheral vascular disease.
    Type: Application
    Filed: September 1, 2009
    Publication date: April 8, 2010
    Inventors: Colin Hutchison, Paul Cockwell, Hermann Göhl, Bernd Krause, Markus Storr