Patents by Inventor PAUL COLIN MICHAEL WINSHIP

PAUL COLIN MICHAEL WINSHIP has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-fused thiophene derivatives and their uses
    Patent number: 11840527
    Abstract: The present invention relates to a new class of non-fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: December 12, 2023
    Assignee: ENYO PHARMA
    Inventors: Eric Meldrum, Benoît De Chassey, Peter Machin, Karine Fabienne Malagu, Paul Colin Michael Winship, Mark Chambers, Jamie David Knight, Roberta Lanaro
  • Thiophene derivatives as antiviral agents
    Patent number: 11807618
    Abstract: The present invention relates to a new class of compounds having an antiviral effect and the uses thereof.
    Type: Grant
    Filed: March 18, 2022
    Date of Patent: November 7, 2023
    Assignee: ENYO PHARMA
    Inventors: Eric Meldrum, Benoît De Chassey, Laëtitia Lines, Jérôme Amaudrut, Benaissa Boubia, Vincent Derain, Fabrice Guillier, Christian Montalbetti, Calum Macleod, Karine Fabienne Malagu, David Robert Vesey, Paul Colin Michael Winship
  • Non-fused thiophene derivatives and their uses
    Patent number: 11767316
    Abstract: The present invention relates to a new class of non-fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: September 26, 2023
    Assignee: ENYO PHARMA
    Inventors: Eric Meldrum, Benoît De Chassey, Peter Machin, Karine Fabienne Malagu, Paul Colin Michael Winship, Jean-Laurent Paparin, Mark Chambers, Jamie David Knight, Roberta Lanaro
  • MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20230133667
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: October 18, 2022
    Publication date: May 4, 2023
    Inventors: Peter Andrew Smith, Tucker Curran Roberts, Robert I. Higuchi, Prasuna Paraselli, Michael F. T. Koehler, Jacob Bradley Schwarz, James John Crawford, Cuong Q. Ly, Emily J. Hanan, Huiyong Hu, Yongsheng Chen, Zhiyong Yu, Paul Colin Michael Winship, Calum MacCleod, Toby Blench
  • Fused thiophene derivatives and their uses
    Patent number: 11603368
    Abstract: The present invention relates to a new class of fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: March 14, 2023
    Assignee: ENYO PHARMA
    Inventors: Eric Meldrum, Benoît De Chassey, Peter Machin, Roberta Lanaro, Calum Macleod, Karine Fabienne Malagu, Nicolas Proisy, David Robert Vesey, Paul Colin Michael Winship, Mark Chambers, Jean-Laurent Paparin
  • ISOINDOLINE DERIVATIVES WHICH BIND TO AN ATP BINDING SITE
    Publication number: 20230061002
    Abstract: The present invention relates to novel probe compounds of formulae I and II defined herein. The present invention also relates to methods of synthesising these novel probe compounds and to their use in assays and screens for determining the binding of a test molecule to the ATP-binding site of a target protein, such as, for example, the Mismatch Repair (MMR) component proteins PMS2 and MLH1, or for determining the location and/or quantity of such target proteins in a biological sample.
    Type: Application
    Filed: January 20, 2021
    Publication date: March 2, 2023
    Inventors: Julian Blagg, Jonathon Richard Anthony Roffey, Paul Colin Michael Winship, Gareth William Langley
  • Fused thiophene derivatives and their uses
    Patent number: 11492347
    Abstract: The present invention relates to a new class of fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: November 8, 2022
    Assignee: ENYO PHARMA
    Inventors: Eric Meldrum, Benoît De Chassey, Peter Machin, Roberta Lanaro, Calum MacLeod, Karine Fabienne Malagu, Nicolas Proisy, David Robert Vesey, Paul Colin Michael Winship, Mark Chambers
  • THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS
    Publication number: 20220213053
    Abstract: The present invention relates to a new class of compounds having an antiviral effect and the uses thereof.
    Type: Application
    Filed: March 18, 2022
    Publication date: July 7, 2022
    Inventors: ERIC MELDRUM, BENOÎT DE CHASSEY, LAËTITIA LINES, JÉRÔME AMAUDRUT, BENAISSA BOUBIA, VINCENT DERAIN, FABRICE GUILLIER, CHRISTIAN MONTALBETTI, CALUM MACLEOD, KARINE FABIENNE MALAGU, DAVID ROBERT VESEY, PAUL COLIN MICHAEL WINSHIP
  • Thiophene derivatives as antiviral agents
    Patent number: 11279683
    Abstract: The present invention relates to a new class of compounds of formula (I) having an antiviral effect and the uses thereof.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: March 22, 2022
    Assignee: ENYO PHARMA
    Inventors: Eric Meldrum, Benoit De Chassey, Laetitia Lines, Jerome Amaudrut, Benaissa Boubia, Vincent Derain, Fabrice Guillier, Christian Montalbetti, Calum MacLeod, Karine Fabienne Malagu, David Robert Vesey, Paul Colin Michael Winship
  • MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20210198316
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: August 13, 2019
    Publication date: July 1, 2021
    Inventors: Peter Andrew SMITH, Tucker Curran ROBERTS, Robert I. HIGUCHI, Prasuna PARASELLI, Michael F. T. KOEHLER, Jacob Bradley SCHWARZ, James John CRAWFORD, Cuong Q. LY, Emily J. HANAN, Huiyong HU, Yongsheng CHEN, Zhiyong YU, Paul Colin Michael WINSHIP, Calum McCleod, Toby Blench
  • NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES
    Publication number: 20210040059
    Abstract: The present invention relates to a new class of non-fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.
    Type: Application
    Filed: February 8, 2019
    Publication date: February 11, 2021
    Inventors: ERIC MELDRUM, BENOÎT DE CHASSEY, PETER MACHIN, KARINE FABIENNE MALAGU, PAUL COLIN MICHAEL WINSHIP, JEAN-LAURENT PAPARIN, MARK CHAMBERS, JAMIE DAVID KNIGHT, ROBERTA LANARO
  • NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES
    Publication number: 20200369655
    Abstract: The present invention relates to a new class of non-fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.
    Type: Application
    Filed: February 8, 2019
    Publication date: November 26, 2020
    Inventors: ERIC MELDRUM, BENOÎT DE CHASSEY, PETER MACHIN, KARINE FABIENNE MALAGU, PAUL COLIN MICHAEL WINSHIP, MARK CHAMBERS, JAMIE DAVID KNIGHT, ROBERTA LANARO
  • FUSED THIOPHENE DERIVATIVES AND THEIR USES
    Publication number: 20200369682
    Abstract: The present invention relates to a new class of fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.
    Type: Application
    Filed: February 8, 2019
    Publication date: November 26, 2020
    Inventors: ERIC MELDRUM, BENOÎT DE CHASSEY, PETER MACHIN, ROBERTA LANARO, CALUM MACLEOD, KARINE FABIENNE MALAGU, NICOLAS PROISY, DAVID RICHARD VESEY, PAUL COLIN MICHAEL WINSHIP, MARK CHAMBERS, JEAN-LAURENT PAPARIN
  • FUSED THIOPHENE DERIVATIVES AND THEIR USES
    Publication number: 20200361924
    Abstract: The present invention relates to a new class of fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.
    Type: Application
    Filed: February 8, 2019
    Publication date: November 19, 2020
    Inventors: ERIC MELDRUM, BENOÎT DE CHASSEY, PETER MACHIN, ROBERTA LANARO, CALUM MACLEOD, KARINE FABIENNE MALAGU, NICOLAS PROISY, DAVID RICHARD VESEY, PAUL COLIN MICHAEL WINSHIP, MARK CHAMBERS
  • MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20200024309
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: August 13, 2019
    Publication date: January 23, 2020
    Inventors: Peter Andrew SMITH, Tucker Curran ROBERTS, Robert I. HIGUCHI, Prasuna PARASELLI, Michael F. T. KOEHLER, Jacob Bradley SCHWARZ, James John CRAWFORD, Cuong Q. LY, Emily J. HANAN, Huiyong HU, Yongsheng CHEN, Zhiyong YU, Paul Colin Michael WINSHIP, Calum McCleod, Toby Blench
  • THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS
    Publication number: 20190352275
    Abstract: The present invention relates to a new class of compounds of formula (I) having an antiviral effect and the uses thereof.
    Type: Application
    Filed: December 28, 2017
    Publication date: November 21, 2019
    Inventors: ERIC MELDRUM, BENOIT DE CHASSEY, LAETITIA LINES, JEROME AMAUDRUT, BENAISSA BOUBIA, VINCENT DERAIN, FABRICE GUILLIER, CHRISTIAN MONTALBETTI, CALUM MACLEOD, KARINE FABIENNE MALAGU, DAVID ROBERT VESEY, PAUL COLIN MICHAEL WINSHIP