Abstract: Several embodiments relate to antigen-binding proteins, such as antibodies, that hind to glycophorin A, In some embodiments, the antigen-binding proteins provided herein are fully human, humanized, or chimeric antibodies, binding fragments and derivatives of such antibodies, and polypeptides that specifically bind glycophorin A, Several embodiments relate to affinity-matured antigen-binding proteins. Several embodiments employ Next Generation Sequencing to predict, screen or otherwise characterize affinity matured candidates. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides.

Abstract: An exemplary detection apparatus includes a housing having one or more sensors of one or more sensor types, an optional port for detachably mounting one or more of the sensors, and an optional motive system associated with a mode of transport for movement in an area of interest. A sensor circuit receives a signal originating from the one or more sensors, identifies the signal, optionally processes the signal data, and packages the raw signal data or processed signal data, as applicable, for transmission over a network. A control circuit establishes communication with the network for sending or receiving sensor data to/from other devices connected to the network, and controls the motive system for moving the apparatus to locations in the area of interest.

Abstract: A lubricant injector includes a body having an inlet at a first end fluidly coupleable to a lubricant source, an outlet, a delivery chamber coupled with the outlet and a bore defined by a substantially circular inner surface with a constant inner diameter and spaced axially from the body inlet, the bore having a first port fluidly connected with the body inlet and a second port disposed between the body inlet and the first port and fluidly connected with the delivery chamber. A generally circular cylindrical piston is disposed within the bore so as to divide the bore into an operating chamber fluidly coupled with the first port and a measuring chamber fluidly coupled with the second port and located axially between the operating chamber and the body first end. The piston has an outer circumferential slidably disposed against the bore inner surface and having a generally constant outside diameter.

Abstract: A lubricant injector includes a body having an inlet fluidly coupleable to a lubricant source, an outlet, and an elongated bore extending along an axis and having an outer end proximal to the body second end, a closed inner end spaced axially from the body first end, a first port, and a second port disposed generally between the bore closed end and the first port. A delivery chamber separate from the bore has an inlet port and an outlet port fluidly coupled with the body outlet. A piston disposed within the bore divides the bore into an operating chamber coupled with the first port and a measuring chamber coupled with the second port. The operating chamber is fluidly coupled with the inlet and the measuring chamber is located between the bore closed end and the operating chamber and is fluidly coupleable with the inlet and alternatively with the delivery chamber.

Abstract: A lubrication system includes a lubricant supply reservoir, a supply line connecting the reservoir with one or more dispenser valves, a return valve and a pump. A control is operatively connected with a pump and with the return valve, the control being configured to operate the pump and the return valve such that a quantity of lubricant within the supply line flows out of the supply line and into the reservoir when a period of storage within the supply line of the quantity of lubricant exceeds an estimated period of effectiveness of the quantity of lubricant or a predetermined portion of the estimated lubricant effectiveness period.

Abstract: A lubricant injector includes a body having an inlet at a first end fluidly coupleable to a lubricant source, an outlet, a delivery chamber coupled with the outlet and a bore defined by a substantially circular inner surface with a constant inner diameter and spaced axially from the body inlet, the bore having a first port fluidly connected with the body inlet and a second port disposed between the body inlet and the first port and fluidly connected with the delivery chamber. A generally circular cylindrical piston is disposed within the bore so as to divide the bore into an operating chamber fluidly coupled with the first port and a measuring chamber fluidly coupled with the second port and located axially between the operating chamber and the body first end. The piston has an outer circumferential slidably disposed against the bore inner surface and having a generally constant outside diameter.

Abstract: A lubricant injector includes a body having an inlet fluidly coupleable to a lubricant source, an outlet, and an elongated bore extending along an axis and having an outer end proximal to the body second end, a closed inner end spaced axially from the body first end, a first port, and a second port disposed generally between the bore closed end and the first port. A delivery chamber separate from the bore has an inlet port and an outlet port fluidly coupled with the body outlet. A piston disposed within the bore divides the bore into an operating chamber coupled with the first port and a measuring chamber coupled with the second port. The operating chamber is fluidly coupled with the inlet and the measuring chamber is located between the bore closed end and the operating chamber and is fluidly coupleable with the inlet and alternatively with the delivery chamber.

Abstract: A lubrication system for lubricating at least one movable machine component includes a lubricant reservoir containing a lubricant and a fluid line fluidly coupled with the reservoir and having an outlet for dispensing the lubricant on or within the machine component. A valve selectively permits lubricant flow through the fluid line so as to dispense a quantity of lubricant through the fluid line outlet. A sensor senses a property of the machine component or the quantity of lubricant. A control is coupled with the sensor and with the valve, the control being configured to receive information from the sensor, to determine an estimated period of effectiveness of the quantity of lubricant using the sensor information, and to operate the valve based on the estimated lubricant effectiveness period so as to dispense another quantity of lubricant on or within the machine component.

Abstract: A lubrication system includes a lubricant supply reservoir, a supply line connecting the reservoir with one or more dispenser valves, a return valve and a pump. A control is operatively connected with a pump and with the return valve, the control being configured to operate the pump and the return valve such that a quantity of lubricant within the supply line flows out of the supply line and into the reservoir when a period of storage within the supply line of the quantity of lubricant exceeds an estimated period of effectiveness of the quantity of lubricant or a predetermined portion of the estimated lubricant effectiveness period.

Abstract: A method of operating a lubrication system for lubricating a bearing in a housing includes the following steps: dispensing a quantity of lubricant within the bearing housing; monitoring a containment period of time during which the lubricant quantity is contained within the housing; determining when the containment time period exceeds a predetermined value of time; and dispensing another quantity of lubricant within the bearing housing when the containment time period exceeds the predetermined time value such that the other quantity of lubricant displaces the quantity of lubricant from the bearing housing.

Abstract: A lubrication system vent valve includes a valve body having a flow passage with an inlet fluidly coupled with a supply and an outlet fluidly coupled with a dispenser, and a vent passage with an inlet port fluidly coupled with the flow passage and an outlet port. A closure element disposed within the vent passage has a threaded portion and is linearly displaceable between an open position where the vent ports are fluidly coupled to permit lubricant flow from the primary passage and out of the body through the vent outlet port, and a closed position at which fluid flow between the vent ports is substantially prevented. A motor has a shaft with a threaded portion engaged with the closure element such that shaft rotation in one direction displaces the closure element toward the closed position and shaft rotation in an opposing direction displaces the element toward the open position.

Abstract: A flow measuring device includes a housing having an inlet, an outlet and a passage extending between the inlet and outlet, a shaft disposed within the housing and rotatable about a central axis and a flow detector mounted on the shaft and disposed partially within the passage, such that fluid flow through the passage rotates the detector about the axis. A magnet is mounted on the shaft and spaced axially from the detector and a sensor disposed within the housing and configured to sense rotation of the magnet as the shaft angularly displaces about the central axis so as to detect angular displacement of the flow detector. Preferably, the sensor includes a switch adjustable from open and closed states when either one of the poles of the magnet is proximal to the switch. A processor is connected with the switch and determines flow volume and/or flow rate through the passage.

Abstract: A lubrication system vent valve includes a valve body having a flow passage with an inlet fluidly coupled with a supply and an outlet fluidly coupled with a dispenser, and a vent passage with an inlet port fluidly coupled with the flow passage and an outlet port. A closure element disposed within the vent passage has a threaded portion and is linearly displaceable between an open position where the vent ports are fluidly coupled to permit lubricant flow from the primary passage and out of the body through the vent outlet port, and a closed position at which fluid flow between the vent ports is substantially prevented. A motor has a shaft with a threaded portion engaged with the closure element such that shaft rotation in one direction displaces the closure element toward the closed position and shaft rotation in an opposing direction displaces the element toward the open position.

Abstract: Signatures indicating potential problems can be used by a predictive support component. The predictive support component can check to see if a signature matches data for a data source associated with the software.

Abstract: The present invention provides an apparatus for venting an airspace formed between an ornamental window and a protective panel. The venting means includes at least one pair of vent openings, one for air to enter the airspace and one for air to exit. These vent openings include a path through the frame holding the protective panel to an interior opening which is to the airspace. The vent openings, the paths and the interior openings must be of adequate size to minimize the range of temperature and moisture within the airspace. It is recommended that effective vent openings are at least one square inch for every 2000-2500 square inches of ornamental window.

Abstract: Signatures indicating potential problems can be used by a predictive support component. The predictive support component can check to see if a signature matches data for a data source associated with the software.

Abstract: A device for dispensing a viscous fluid, such as grease gun for dispensing lubricant. The grease gun delivers lubricant with a selectable variation in pressure and/or output. It includes a reservoir, a pump having a reciprocating plunger, an electric motor driving the pump, and a variable speed transmission for transmitting power from the motor to the pump. The transmission has at least two different output speed settings adapted to be selected for reciprocating the plunger at different cyclical frequencies. A cycle indicator provides an indication corresponding to a quantity of lubricant dispensed. Embodiments of the grease gun include a pressure relief valve which inhibits damage due to an over-pressure condition, and a circuit breaker which inhibits damage due to electrical overload.

Abstract: The present invention provides an apparatus for venting an airspace formed between an ornamental window and a protective panel. The venting means includes at least one pair of vent openings, one for air to enter the airspace and one for air to exit. These vent openings include a path through the frame holding the protective panel to an interior opening which is to the airspace. The vent openings, the paths and the interior openings must be of adequate size to minimize the range of temperature and moisture within the airspace. It is recommended that effective vent openings are at least one square inch for every 2000-2500 square inches of ornamental window.

Abstract: A case for holding eyeglasses defines the head band of an eyeglass retainer. The bow retaining straps of the retainer are secured to the outer edges of the case/head band. A separate, flexible sheet conforms to the shape of and is secured to the head band case for defining a pocket between the base and the sheet. A through slot in the sheet provides access to the pocket, permitting the folded eyeglasses to be inserted through the slot and encased between the base and the sheet while attached to the retaining straps.