Patents by Inventor Paul Czodrowski
Paul Czodrowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11939314Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.Type: GrantFiled: October 12, 2021Date of Patent: March 26, 2024Assignee: MERCK PATENT GMBHInventors: Dieter Dorsch, Mathilde Muzerelle, Lars Burgdorf, Margarita Wucherer-Plietker, Paul Czodrowski, Christina Esdar, Christos Tsaklakidis
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Publication number: 20230028687Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.Type: ApplicationFiled: October 12, 2021Publication date: January 26, 2023Applicant: MERCK PATENT GMBHInventors: Dieter DORSCH, Mathilde MUZERELLE, Lars BURGDORF, Margarita WUCHERER-PLIETKER, Paul CZODROWSKI, Christina ESDAR, Christos TSAKLAKIDIS
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Patent number: 11186562Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.Type: GrantFiled: February 20, 2020Date of Patent: November 30, 2021Assignee: MERCK PATENT GMBHInventors: Dieter Dorsch, Mathilde Muzerelle, Lars Burgdorf, Margarita Wucherer-Plietker, Paul Czodrowski, Christina Esdar, Christos Tsaklakidis
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Patent number: 11174241Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in Claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.Type: GrantFiled: February 20, 2020Date of Patent: November 16, 2021Assignee: MERCK PATENT GMBHInventors: Dieter Dorsch, Mathilde Muzerelle, Lars Burgdorf, Margarita Wucherer-Plietker, Paul Czodrowski, Christina Esdar, Christos Tsaklakidis
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Publication number: 20200190055Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in Claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.Type: ApplicationFiled: February 20, 2020Publication date: June 18, 2020Applicant: MERCK PATENT GMBHInventors: Dieter DORSCH, Mathilde MUZERELLE, Lars BURGDORF, Margarita WUCHERER-PLIETKER, Paul CZODROWSKI, Christina ESDAR, Christos TSAKLAKIDIS
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Publication number: 20200190054Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.Type: ApplicationFiled: February 20, 2020Publication date: June 18, 2020Applicant: MERCK PATENT GMBHInventors: Dieter DORSCH, Mathilde MUZERELLE, Lars BURGDORF, Margarita WUCHERER-PLIETKER, Paul CZODROWSKI, Christina ESDAR, Christos TSAKLAKIDIS
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Patent number: 10669251Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in Claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.Type: GrantFiled: December 16, 2016Date of Patent: June 2, 2020Assignee: MERCK PATENT GMBHInventors: Dieter Dorsch, Mathilde Muzerelle, Lars Burgdorf, Margarita Wucherer-Plietker, Paul Czodrowski, Christina Esdar, Christos Tsaklakidis
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Publication number: 20190023685Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in Claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.Type: ApplicationFiled: December 16, 2016Publication date: January 24, 2019Applicant: MERCK PATENT GMBHInventors: Dieter DORSCH, Mathilde MUZERELLE, Lars BURGDORF, Margarita WUCHERER-PLIETKER, Paul CZODROWSKI, Christina ESDAR, Christos TSAKLAKIDIS
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Patent number: 9884814Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.Type: GrantFiled: December 16, 2013Date of Patent: February 6, 2018Assignee: MERCK PATENT GMBHInventors: Christos Tsaklakidis, Markus Klein, Paul Czodrowski
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Patent number: 9732032Abstract: Compounds of the formula I in which R1, R4, R, X1, X2, X3, X4, q and W have the meanings indicated in Claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.Type: GrantFiled: October 17, 2013Date of Patent: August 15, 2017Assignee: MERCK PATENT GMBHInventors: Christos Tsaklakidis, Wolfgang Staehle, Brigitta Leuthner, Paul Czodrowski
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Patent number: 9670142Abstract: Compounds of the formula I in which R1, R4, R6, R, X1, X2, X3, X4, q and W have the meanings indicated in claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.Type: GrantFiled: May 9, 2014Date of Patent: June 6, 2017Assignee: Merck Patent GmbHInventors: Christos Tsaklakidis, Wolfgang Staehle, Birgitta Leuthner, Paul Czodrowski, Thomas Fuchss
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Publication number: 20160264517Abstract: Compounds of the formula I in which R1, R4, R, X1, X2, X3, X4, q and W have the meanings indicated in Claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.Type: ApplicationFiled: October 17, 2013Publication date: September 15, 2016Applicant: MERCK PATENT GMBHInventors: Christos TSAKLAKIDIS, Wolfgang STAEHLE, Brigitta LEUTHNER, Paul CZODROWSKI
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Publication number: 20160130214Abstract: Compounds of the formula I in which R1, R4, R6, R, X1, X2, X3, X4, q and W have the meanings indicated in claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.Type: ApplicationFiled: May 9, 2014Publication date: May 12, 2016Applicant: Merck Patent GmbHInventors: Christos TSAKLAKIDIS, Wolfgang STAEHLE, Birgitta LEUTHNER, Paul CZODROWSKI, Thomas FUCHSS
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Publication number: 20150361037Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.Type: ApplicationFiled: December 16, 2013Publication date: December 17, 2015Applicant: Merck Patent GmbHInventors: Christos TSAKLAKIDIS, Markus KLEIN, Paul CZODROWSKI
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Patent number: 9102675Abstract: Compounds of the formula (I) in which R1, R2, X and Y have the meanings indicated in claim 1, are inhibitors of TBK1 and IKK? and can be employed, inter alia, for the treatment of cancer and inflammatory diseases.Type: GrantFiled: October 30, 2012Date of Patent: August 11, 2015Assignee: MERCK PATENT GMBHInventors: Dieter Dorsch, Guenter Hoelzemann, Hans-Michael Eggenweiler, Paul Czodrowski
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Publication number: 20140323481Abstract: Compounds of the formula (I) in which R1, R2, X and Y have the meanings indicated in claim 1, are inhibitors of TBK1 and IKK? and can be employed, inter alia, for the treatment of cancer and inflammatory diseases.Type: ApplicationFiled: October 30, 2012Publication date: October 30, 2014Applicant: MERCK PATENT GMBHInventors: Dieter Dorsch, Guenter Hoelzemann, Hans-Michael Eggenweiler, Paul Czodrowski
