Abstract: A non-instrumented biochemical assay device, such as a device for the processing of clinical specimens for molecular diagnostic applications. In one embodiment, an assay device comprises a lid which covers a reagent tube, which is disposed on a base. The platform utilizes chemical heating and optional temperature modulation by phase change material to prepare the sample and to amplify the target nucleic acid using Loop-Mediated Isothermal Amplification. The device features a simple indicator for a positive reaction, for example turbidity or fluorescence.

Abstract: A torso orthosis including a chest support securable to a patient. The chest support includes a sternal plate securable in a substantially fixed position with respect to the patient's chest. The chest support also includes a sternal bar and a connection between the sternal plate and the sternal bar. The connection allows the sternal bar to move longitudinally with respect to the sternal plate so that the sternal plate remains in the substantially fixed position with respect to the patient's chest as the patient's torso flexes. The connection can also allow the sternal bar to pivot with respect to the sternal plate as the patient's torso flexes.