Patents by Inventor Paul D. Stull

Paul D. Stull has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for detecting the presence of in a test sample
    Patent number: 8105779
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: January 31, 2012
    Inventors: Melissa M. Cunningham, Paul D. Stull, William G. Weisburg
  • Compositions and Methods For Detecting The Presence Of Cryptosporidium Parvum In A Test Sample
    Publication number: 20110269133
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Application
    Filed: July 14, 2011
    Publication date: November 3, 2011
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Melissa M. CUNNINGHAM, Paul D. STULL, William G. WEISBURG
  • Compositions and methods for detecting the presence of cryptosporidium organisms in a test sample
    Patent number: 8008017
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: August 30, 2011
    Assignee: Gen-Probe Incorporated
    Inventors: Melissa M. Cunningham, Paul D. Stull, William G. Weisburg
  • Compositions and Methods For Detecting The Presence Of Cryptosporidium Organisms In A Test Sample
    Publication number: 20100003693
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Application
    Filed: September 8, 2009
    Publication date: January 7, 2010
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Melissa M. CUNNINGHAM, Paul D. STULL, William G. WEISBURG
  • Method for obtaining purified RNA from viable oocysts
    Patent number: 7585631
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Crytosporidium organisms, and Crytosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: September 8, 2009
    Assignee: Gen-Probe Incorporated
    Inventors: Melissa M. Cunningham, Paul D. Stull, William G. Weisburg
  • Compositions, methods and kits for determining the presence of organisms in a test sample
    Patent number: 7081527
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Grant
    Filed: September 11, 2001
    Date of Patent: July 25, 2006
    Assignee: Gen-Probe Incorporated
    Inventors: Melissa M. Cunningham, Paul D. Stull, William G. Weisburg
  • Compositions, methods and kits for determining the presence of cryptosporidium parvum organisms in a test sample
    Publication number: 20020146717
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Application
    Filed: September 11, 2001
    Publication date: October 10, 2002
    Inventors: Melissa M. Cunningham, Paul D. Stull, William G. Weisburg
  • Compositions, methods and kits for determining the presence of cryptosporidium organisms in a test sample
    Publication number: 20020055116
    Abstract: The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvumorganisms in particular, which are useful for determining the presence of Cryptosporidium organisms in a test sample. The oligonucleotides of the present invention include hybridization assay probes, helper probes and amplification primers. The present invention further describes a novel method for obtaining purified ribonucleic acid from viable oocysts.
    Type: Application
    Filed: September 11, 2001
    Publication date: May 9, 2002
    Inventors: Melissa M. Cunningham, Paul D. Stull, William G. Weisburg
  • Promoter-sequestered oligonucleoside and method of use
    Patent number: 6025133
    Abstract: The present invention features "promoter-sequestered" oligonucleosides and the use of such oligonucleosides to achieve "target-triggered" amplification. A promoter-sequestered oligonucleoside contains a contiguous nucleic acid sequence which forms a stem-loop structure in the absence of a target sequence. The stem-loop structure contains a single-stranded loop region and a double-stranded stem region. The single-stranded loop contains all, or a portion of, an RNA polymerase promoter sequence. The stem is produced from two substantially complementary nucleic acid sequences able to form an intramolecular hybrid. The secondary structure of the stem decreases the accessibility of the loop promoter sequence to form a functional double-stranded promoter.
    Type: Grant
    Filed: December 30, 1996
    Date of Patent: February 15, 2000
    Assignee: Gen-Probe Incorporated
    Inventors: Paul D. Stull, Kristi K. Myers, Michael M. Becker
  • Method for detection of specific nucleic acid sequences
    Patent number: 5516641
    Abstract: A kit is disclosed for a method for detecting the presence of a target polynucleotide sequence. The kit comprises a first polynucleotide sequence and a second polynucleotide sequence complementary to non-contiguous portions of a target polynucleotide sequence, which first and second sequences are covalently attached when they are hybridized to the target sequence. The presence of the covalently attached first and second sequences is related to the presence of the target polynucleotide sequence. The invention may be applied to target polynucleotide sequences in DNA or RNA. Specific target polynucleotide sequences of interest will frequently be characteristic of particular microorganisms, viruses, viroids, or genetic characteristics, including genetic abnormalities.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: May 14, 1996
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Edwin F. Ullman, Thomas C. Goodman, Paul D. Stull
  • Compositions for the detection of Chlamydia trachomatis
    Patent number: 5514551
    Abstract: Oligonucleotides and methods for the amplification and specific detection of Chlamydia trachomatis. The invention relates to amplification oligonucleotides capable of amplifying Chlamydia trachomatis nucleotide sequences and to probes and helper oligonucleotides for the specific detection of Chlamydia trachomatis nucleic acids. The invention also relates to methods for using the oligonucleotides of the present invention and specific combinations and kits useful for the detection of Chlamydia trachomatis.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: May 7, 1996
    Assignee: Gen-Probe Incorporated
    Inventors: Yeasing Yang, Paul D. Stull, Marc Spingola
  • Methods for the detection of Chlamydia trachomatis
    Patent number: 5512445
    Abstract: Oligonucleotides and methods for the amplification and specific detection of Chlamydia trachomatis. The invention relates to amplification oligonucleotides capable of amplifying Chlamydia trachomatis nucleotide sequences and to probes and helper oligonucleotides for the specific detection of Chlamydia trachomatis nucleic acids. The invention also relates to methods for using the oligonucleotides of the present invention and specific combinations and kits useful for the detection of Chlamydia trachomatis.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: April 30, 1996
    Assignee: Gen-Probe Incorporated
    Inventors: Yeasing Yang, Paul D. Stull, Marc Spingola
  • Method for detection of specific nucleic acid sequences
    Patent number: 5185243
    Abstract: A method is disclosed for detecting the presence of a target nucleotide sequence in a polynucleotide. The method comprises hybridizing a first nucleotide sequence and a second nucleotide sequence to non-contiguous portions of a target nucleotide sequence, covalently attaching the first and second sequences when they are hybridized to the target sequence, and determining the presence of covalently attached first and second sequences. The presence of the covalently attached first and second sequences is related to the presence of the target nucleotide sequence. The invention may be applied to target nucleotide sequences in DNA or RNA. Specific target nucleotide sequences of interest will frequently be characteristic of particular microorganisms, viruses, viroids, or genetic characteristics, including genetic abnormalities.
    Type: Grant
    Filed: August 25, 1988
    Date of Patent: February 9, 1993
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Edwin F. Ullman, Thomas C. Goodman, Paul D. Stull