Patents by Inventor Paul David Cannon

Paul David Cannon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for screening human intestinal Npt2B modulatory agents
    Patent number: 7803562
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: September 28, 2010
    Assignee: Roche Palo Alto LLC
    Inventors: Paul David Cannon, Suryanarayana Sankuratri
  • Human intestinal NPT2B
    Publication number: 20090170122
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Application
    Filed: December 18, 2007
    Publication date: July 2, 2009
    Inventors: Paul David Cannon, Suryanarayana Sankuratri
  • Human intestinal Npt2B
    Patent number: 7368530
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Grant
    Filed: January 17, 2002
    Date of Patent: May 6, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: Paul David Cannon, Suryanarayana Sankuratri
  • Human intestinal Npt2B
    Publication number: 20020156266
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Application
    Filed: January 17, 2002
    Publication date: October 24, 2002
    Inventors: Paul David Cannon, Suryanarayana Sankuratri
  • Human intestinal Npt2B
    Patent number: 6380374
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Grant
    Filed: February 8, 2000
    Date of Patent: April 30, 2002
    Assignee: Roche Bioscience
    Inventors: Paul David Cannon, Suryanarayana Sankuratri
  • Matrix metalloprotease inhibitors
    Patent number: 5773428
    Abstract: Compounds of formula (I): ##STR1## as single stereoisomers or mixtures thereof and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as interstitial collagenases, and are useful in the treatment of mammals having disease states alleviated by the inhibition of such matrix metalloproteases, for example arthritic diseases or bone resorption diseases, such as osteoporosis.
    Type: Grant
    Filed: February 5, 1996
    Date of Patent: June 30, 1998
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Arlindo Lucas Castelhano, Teng Jiam Liak, Stephen Horne, Alexander Krantz, Zhengyu Yuan, Jian Jeffrey Chen, Paul David Cannon, Hal Van Wart