Abstract: A far-UVC device for eliminating airborne pathogens includes a plenum, a fan, an LED array, and a filter. Air enters through an inlet and passes through the plenum until it exits out the outlet. The filter is located within the plenum adjacent to either the outlet or the inlet. The LED array emits a UV light on the passing air to inactivate airborne pathogens. The fan regulates the flow rate of the air through the plenum. The fan maintains a positive flow of air through the device and eventually exhausts the disinfected air out the outlet. One or more baffles are located within the plenum to direct the air flow through the device.

Abstract: The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).

Abstract: In a method of producing symmetrical carbon fiber reinforced composite parts, a plurality of sheets of fibrous material configured as a single structure are positioned on a tool surface where the single structure is comprised of a first composite part joined to a symmetric, second composite part. The single structure is infused with resin and cured on the tool surface, producing a single cured structure comprised of a first cured composite part joined to a second cured composite part. The single cured structure is then divided along a dividing plane, producing the symmetric first cured composite part and second cured composite part.

Abstract: A cleaning device including a spray bottle, roller, and scrubber apparatus. The roller is positioned about the reservoir of the spray bottle. The removable scrubber is positioned in the base of the spray bottle. The roller uses a washable absorbent pad to clean surfaces with cleaning solution deposited by the spray bottle. The spray mechanism is held in two grips, a spray grip and a reverse grip in order to make use of the spray mechanism and the roller, respectively.

Abstract: Aspects of a data environment, such as the creation, provisioning, and management of data stores and instances, are managed using a separate control environment. A user can call into an externally-facing interface of the control environment, the call being analyzed to determine actions to be performed in the data environment. A monitoring component of the control plane also can periodically communicate with the data environment to determine any necessary actions to be performed, such as to recover from faults or events in the data environment. A workflow can be instantiated that includes tasks necessary to perform the action. For each task, state information can be passed to a component in the data environment operable to perform the task, until all tasks for an action are completed. Data in the data environment can be accessed directly using an externally-facing interface of the data environment, without accessing the control plane.

Abstract: Provided are multi-specific antibodies that target both a cellular efflux pump and a cancer-associated antigen as well as pharmaceutical compositions, nucleic acids, recombinant expression vectors, cells, and kits that include or encode such multi-specific antibodies. Methods of treating a subject for a cancer that include administering to the subject a multi-specific antibody that targets both a cellular efflux pump and a cancer-associated antigen are also provided. Provided as well are methods of generating the described multi-specific antibodies and reagents related thereto, including genetically modified cell lines useful in the subject methods and methods of making such genetically modified cell lines.

Abstract: Described herein are systems and methods for favorably coordinating a timing relationship between a musculoskeletal activity cycle and a cardiac cycle of a user. A method may include repetitively detecting a signal that correlates to a blood volume in the user; determining an actual value of the signal that varies with the timing relationship; computing a trend of the actual value of the signal; and adjusting the movement guidance based on the trend of the actual value. A system may include a prompt device configured to provide recurrently a movement guidance to the user for guiding performance of the rhythmic musculoskeletal activity; a sensor configured to provide a signal that correlates to a blood volume in the user; and a processor configured to determine an actual value of the signal that varies with the timing relationship and to adjust the movement guidance based on the trend of the actual value.

Abstract: A system for inductive power transfer that may selectively transmit power in a plurality of modes based on characteristics of a power receiver and determine which transmitter coils to drive based on received signal strength information. The inductive power transfer transmitter may detect characteristics of the power receiver in order to control the mode of the power transfer and selectively control which transmitter coils are driven based on signal strength information received from a power receiver. The power transmitter may have slugs formed of a magnetically permeable material within common coil winding openings and the transmitter coils may consists of a plurality of parallel windings.

Abstract: A method of manufacturing a rotor for a generator of an aircraft engine. The method includes providing a rotor body; mounting at least one magnet on the rotor body; wrapping a tow around the rotor body and the at least one magnet to form a wrapped tow having a plurality of layers overlaid in the radial direction; and curing the wrapped tow to form at least a part of a fibre-reinforced composite sleeve configured to retain the at least one magnet on the rotor body. The step of wrapping includes applying a controlled tension to the tow during wrapping. The controlled tension is varied according to the radial position of the layer being wrapped.

Abstract: A system for performing industrial automation control may include an audio device that receives audio data from an element in an industrial automation system. The audio device may determine orientation data based on the audio data. In addition, the audio device may determine an automation command to control a machine in the industrial automation system based on the audio data and the orientation data. After determining the automation command, the audio device may implement a first control action for the machine based at least in part on the automation command, where the first control action causes the machine to adjust an operation.

Abstract: A system for performing industrial automation control may include an audio device that receives audio data from an element in an industrial automation system. The audio device may determine orientation data based on the audio data. In addition, the audio device may determine an automation command to control a machine in the industrial automation system based on the audio data and the orientation data. After determining the automation command, the audio device may implement a first control action for the machine based at least in part on the automation command, where the first control action causes the machine to adjust an operation.

Abstract: In an embodiment, a method includes: adjusting a first flight control device of a rotorcraft to control flight around a first axis of the rotorcraft, the first flight control device exercising flight control authority around the first axis of the rotorcraft; detecting a failure of the first flight control device; transitioning at least a portion of the flight control authority around the first axis of the rotorcraft from the first flight control device to a second flight control device of the rotorcraft, the transitioning being performed automatically in response to detecting the failure of the first flight control device; and adjusting the second flight control device to control flight around the first axis of the rotorcraft, the second flight control device being adjusted by a first control process when the rotorcraft is in a first flight mode, the second flight control device being adjusted by a second control process when the rotorcraft is in a second flight mode.

Abstract: A switching device is implemented in a network-attachable data transfer device to provide data storage access to other such devices. In some embodiments, network-attachable data transfer devices are arranged in a clustered configuration to provide various computational and storage services. When one or more devices of the cluster fails, various implementations associated with the switching device, via an external data interface, provide operational mitigation, optimized data recovery, and efficient reinstatement of normal operation of the cluster.

Abstract: The present disclosure describes depth correlation tools and associated methods which do not require wireline depth correlation runs.

Abstract: A fluid device generally comprises a staging reservoir which may receive a volume of fluid flowing from a primary reservoir via a coupler upon operation of an actuator, wherein the staging reservoir is usable to measure fluid within the device in order to dispense a desired amount of fluid.

Abstract: Provided is a reel for a conductor of an electric fence. The reel includes a bobbin, a frame for supporting the bobbin, and a connector. The connector can be two jaws and can have passages to connect the reel to a support such as a conductor of an existing fence or a tube of a vehicle. One of the jaws can be wide for stability. The connector can have an electrical conductor for connecting to the support and electrifying the conductor. The connector can also be operated by a trigger and can have a locking mechanism. The frame can be a one-piece frame made of plastics material. The reel can have a spreader and a hot-up bar. The reel can have a crank that can be disengaged from the bobbin and a brake that is applied when the crank is disengaged.

Abstract: A surgical humidification system includes a source of gas flow and a humidifier that receives the gas flow and outputs a humidified gas to a delivery conduit. The delivery conduit has an outlet and a suitable interface, such as a diffuser, is connected to the outlet. The interface can be positioned near or within an open surgical cavity of a patient to supply the humidified gas to the cavity. The system also includes a pressure relief arrangement that operates to relieve pressure from the system above a normal operating pressure. The pressure relief arrangement can be located in a non-sterile portion of the system, such as upstream from the humidifier, for example.

Abstract: A system for fire suppression comprising: a container; an agitator; a pump; a distribution head; and a control module; wherein the container is configured to store a fire retardant; wherein the agitator is housed within the container; and wherein the pump is configured to draw the fire retardant to the distribution head; wherein the agitator is configured to periodically agitate the fire retardant.

Abstract: Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy. For example, the dialysis systems include disposable cartridge and patient tubing sets that are easily installed on the dialysis system and automatically align the tubing set, sensors, venous drip chamber, and other features with the corresponding components on the dialysis system. Methods of use are also provided, including automated priming sequences, blood return sequences, and dynamic balancing methods for controlling a rate of fluid transfer during different types of dialysis, including hemodialysis, ultrafiltration, and hemodiafiltration.