Patents by Inventor Paul Di Cesare

Paul Di Cesare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210008054
    Abstract: The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. CDK9 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
    Type: Application
    Filed: April 30, 2020
    Publication date: January 14, 2021
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Dominik HAUDENSCHILD, Paul DI CESARE, Jasper YIK, Blaine CHRISTIANSEN
  • Patent number: 10639302
    Abstract: The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. CDK9 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: May 5, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Dominik Haudenschild, Paul Di Cesare, Jasper Yik, Blaine Christiansen
  • Publication number: 20190255034
    Abstract: The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. CDK9 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
    Type: Application
    Filed: November 20, 2018
    Publication date: August 22, 2019
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Dominik HAUDENSCHILD, Paul Di CESARE, Jasper YIK, Blaine CHRISTIANSEN
  • Patent number: 10172844
    Abstract: The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. CDK9 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: January 8, 2019
    Assignee: The Regents of the University of California
    Inventors: Dominik Haudenschild, Paul Di Cesare, Jasper Yik, Blaine Christiansen
  • Publication number: 20170246156
    Abstract: The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. CDK9 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
    Type: Application
    Filed: November 18, 2016
    Publication date: August 31, 2017
    Applicant: The Regents of the University of California
    Inventors: Dominik HAUDENSCHILD, Paul Di CESARE, Jasper YIK, Blaine CHRISTIANSEN
  • Patent number: 9498471
    Abstract: The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. CDK9 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: November 22, 2016
    Assignee: The Regents of the University of California
    Inventors: Dominik Haudenschild, Paul Di Cesare, Jasper Yik, Blaine Christiansen
  • Patent number: 9133259
    Abstract: The present invention relates to protein complexes or scaffold comprising cartilage oligomeric matrix protein (COMP) polypeptides bound to one or more growth factors, and methods of their use in promoting chondrogenesis and/or osteogenesis, and repair of cartilage and bone lesions.
    Type: Grant
    Filed: September 14, 2011
    Date of Patent: September 15, 2015
    Assignee: The Regents of the University of California
    Inventors: Dominik Haudenschild, Paul Di Cesare, Jasper Yik
  • Publication number: 20150105423
    Abstract: The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. CDK9 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
    Type: Application
    Filed: October 19, 2012
    Publication date: April 16, 2015
    Inventors: Dominik Haudenschild, Paul Di Cesare, Jasper Yik, Blaine Christiansen
  • Publication number: 20130315889
    Abstract: The present invention relates to protein complexes or scaffold comprising cartilage oligomeric matrix protein (COMP) polypeptides bound to one or more growth factors, and methods of their use in promoting chondrogenesis and/or osteogenesis, and repair of cartilage and bone lesions.
    Type: Application
    Filed: September 14, 2011
    Publication date: November 28, 2013
    Applicant: The Regents of the University of California
    Inventors: Dominik Haudenschild, Paul Di Cesare, Jasper Yik
  • Patent number: 5938676
    Abstract: A scalpel of the present invention includes an elongate handle defining a longitudinal axis and having a proximal end and a distal end. The scalpel of the invention further includes a cartridge that is removably mounted to the handle. The cartridge has blade holder with a proximal end and a distal end with a blade fixedly attached that is disposed so that the blade projects distally outwardly when the cartridge is mounted to the handle. The cartridge also includes a shield that is slidably mounted onto the blade holder for movement between a distal position where the shield substantially prevents inadvertent access to the blade and a proximal position where the shield substantially surrounds a portion of the handle and the blade is exposed for use. The cartridge is releasably mountable on the handle. The shield is substantially prevented from movement to the proximal position unless the cartridge is mounted on the handle and not dismountable from the handle unless the shield is in the distal position.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: August 17, 1999
    Assignee: Becton, Dickinson & Company
    Inventors: Simon Cohn, Paul Di Cesare, Michael J. Carter, Jon D. Swenson, Ann C. Eckert, Noel Gharibian, Craig D. Newman
  • Patent number: D502542
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: March 1, 2005
    Assignee: Becton Dickinson and Company
    Inventors: Simon Cohn, Bart D. Peterson, Glade Harold Howell, John R. Montgomery, Paul Di Cesare
  • Patent number: D482122
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: November 11, 2003
    Assignee: Becton Dickinson and Company
    Inventors: Simon Cohn, Glade Harold Howell, John R. Montgomery, Paul Di Cesare, Bart D. Peterson
  • Patent number: D482449
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: November 18, 2003
    Assignee: Becton Dickinson and Company
    Inventors: Simon Cohn, Glade Harold Howell, John R. Montgomery, Paul Di Cesare, Bart D. Peterson
  • Patent number: D482788
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: November 25, 2003
    Assignee: Becton Dickinson and Company
    Inventors: John R. Montgomery, Paul Di Cesare, Glade Harold Howell, Simon Cohn
  • Patent number: D483123
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: December 2, 2003
    Assignee: Becton Dickinson and Company
    Inventors: John R. Montgomery, Paul Di Cesare, Glade Harold Howell, Simon Cohn
  • Patent number: D483124
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: December 2, 2003
    Assignee: Becton Dickinson and Company
    Inventors: Bart D. Peterson, Glade Harold Howell, Simon Cohn, John R. Montgomery, Paul Di Cesare, Chris N. Cindrich
  • Patent number: D486232
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: February 3, 2004
    Assignee: Becton Dickinson and Company
    Inventors: Bart D Peterson, Glade Harold Howell, Simon Cohn, John R. Montgomery, Paul Di Cesare
  • Patent number: D489457
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: May 4, 2004
    Assignee: Becton Dickinson and Company
    Inventors: Simon Cohn, Glade Harold Howell, John R. Montgomery, Paul Di Cesare, Bart D. Peterson
  • Patent number: D490153
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: May 18, 2004
    Assignee: Becton Dickinson and Company
    Inventors: John R. Montgomery, Paul Di Cesare, Glade Harold Howell, Simon Cohn, Bart D. Peterson
  • Patent number: D490154
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: May 18, 2004
    Assignee: Becton, Dickinson and Company
    Inventors: Glade Harold Howell, Simon Cohn, John R. Montgomery, Paul Di Cesare