Patents by Inventor Paul Diaz

Paul Diaz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180184644
    Abstract: The present invention relates to stabilization of cells at ambient temperatures. More particularly, the present invention relates to formulations, compositions, kits and methods that allow dehydration and rehydration of cells and dramatically increased recovery of functional cells after dry storage at room temperature.
    Type: Application
    Filed: December 21, 2017
    Publication date: July 5, 2018
    Inventors: Judy MULLER-COHN, Paul DIAZ, Rolf MULLER, Vasco LIBERAL, Albert PEREZ-LADAGA
  • Publication number: 20170202211
    Abstract: The present invention relates to the stabilization of one or more metabolically-active cell in a blood sample at ambient temperatures. In particular, formulations, compositions, articles of manufacture, kits and methods for substantially stable storage of one or more metabolically-active cell in a blood sample at ambient temperatures are provided.
    Type: Application
    Filed: June 9, 2015
    Publication date: July 20, 2017
    Inventors: Rolf MULLER, Robyn RABAN, Scott WHITNEY, Paul DIAZ
  • Publication number: 20170198335
    Abstract: Provided herein are formulations for the stabilization of one or more polypeptide or nucleic acid molecule in a native, non-denatured state at ambient temperatures. Also provided are compositions, articles of manufacture, kits and methods for substantially stable storage of one or more polypeptide or nucleic acid molecule in a native, non-denatured, and/or functionally active conformation substantially free on intracellular polypeptides and nucleic acids at ambient temperatures are provided. Also provided are formulations for the stabilization of one or more exosome at ambient temperatures, and compositions, articles of manufacture, kits and methods of use.
    Type: Application
    Filed: June 9, 2015
    Publication date: July 13, 2017
    Applicant: Biomatrica, Inc.
    Inventors: Rolf MULLER, Scott WHITNEY, Paul DIAZ
  • Publication number: 20170196220
    Abstract: Provided herein are formulations and methods for the stabilization of one or more thrombocytes at ambient temperatures. Also provided are formulations and methods for the stabilization of one or more thrombocytes in an inactivated state in a blood sample at ambient temperatures. Further provided are articles of manufacture and kits and methods for substantially stable storage of one or more thrombocyte at ambient temperatures.
    Type: Application
    Filed: June 9, 2015
    Publication date: July 13, 2017
    Inventors: Rolf MULLER, Joel DESHARNAIS, Steven P. WILKINSON, Victoria ARENDT, Paul DIAZ
  • Patent number: 7145926
    Abstract: RF excited gas laser consists of a laser tube having external surfaces; a power supply compartment having elongated external fins and a pair of endplates on its opposite ends and wherein laser tube is placed between and is flexibly attached to the endplates; a sheet-metal cover mounted to the endplates and to power supply compartment and forming a laser assembly and having at least one pair of intake openings and at least one pair of exhaust openings for the cooling air to flow through the laser assembly by entering the laser assembly through the intake openings and flowing over power supply external fins and over laser tube external surfaces and then exiting through the exhaust openings. Present invention is characterized by lower cost and more efficient forced air cooling laser tube and RF power supply.
    Type: Grant
    Filed: January 22, 2004
    Date of Patent: December 5, 2006
    Inventors: Peter Vitruk, James Schemmer, Paul Diaz
  • Publication number: 20060205026
    Abstract: A parallel inducible cell-based kinase screen (PICKS) includes a plurality of cells that express a kinase gene under the control of an inducer and a reporter gene, wherein the cells are derived from a single cell line, and wherein the reporter gene generate a signal in response to catalytic activity or inhibition of the expressed kinases. Particularly preferred systems include cells expressing kinases from a single kinase signaling pathway, kinases from a kinase family, and/or kinases from various different kinase signaling pathways. Consequently, contemplated systems provide a platform for screening for novel kinase inhibitors, inhibition specificity of particular kinase inhibitors, and for analysis of inter-pathway and/or intra-pathway inhibition of a kinase inhibitor.
    Type: Application
    Filed: December 19, 2002
    Publication date: September 14, 2006
    Applicant: Valeant Research & Development
    Inventors: Zhi Hong, William Ricketts, Paul Diaz
  • Patent number: 7079739
    Abstract: A flexible hollow waveguide for high efficiency transmission of laser light, comprising: (a) metal cladding tube having interior surface; and (b) elongated bent ribbon of a substrate material; said ribbon having concave interior surface and convex exterior surface and first and second edges therebetween; said ribbon is positioned in said metal cladding tube; said interior surface of the metal cladding tube engaging the said convex exterior surface of the ribbon to hold said first and second edges together and to define an elongated seam therebetween; and (c) first metal layer on the said concave interior surface of the said ribbon; said first metal layer having a elongated discontinuity defined by the said seam; and (d) seamless light reflective second metal layer formed on top of the first metal layer; and (e) seamless light-reflectivity enhancing dielectric layer formed on top of the said second metal layer.
    Type: Grant
    Filed: November 26, 2004
    Date of Patent: July 18, 2006
    Inventors: Peter Vitruk, Paul Diaz
  • Publication number: 20040179570
    Abstract: RF excited gas laser according to present invention consists of an elongated electronics compartment having elongated external fins; an RF power supply placed inside electronics compartment; a pair of endplates attached to the opposite ends of the electronics compartment; a sealed laser tube comprising of a metal tube having an external surface, a pair of endcaps at the opposite ends of the metal tube forming a vacuum envelope for containing a laser gas, a pair of elongated electrodes inside of the metal tube configured for coupling to said RF power supply through RF coupling means; laser resonator mirrors placed on the endcaps at the opposite ends of the tube forming a laser resonator aligned with the RF gas plasma discharge produced between said electrodes; a sheet-metal cover enclosing the laser tube and the electronics compartment forming a laser assembly having at least one pair of intake openings and at least one pair of exhaust openings for the cooling air to flow through the laser assembly; and at lea
    Type: Application
    Filed: January 22, 2004
    Publication date: September 16, 2004
    Inventors: Peter Vitruk, James Schemmer, Paul Diaz