Abstract: Provided herein is a magnetic apparatus for collecting superparamagnetic particles from a subject. The superparamagnetic particles are previously injected into the subject and have ligands bound thereto that are specific for one or more non-cell biomarkers. In one embodiment, the superparamagnetic particles are injected into and retrieved from a cavity such as a joint cavity. These compositions and methods allow for the sequestration and removal of inflammatory mediators, as both a diagnostic of the local immune response and a therapeutic that can reduce inflammation in the local disease environment.

Abstract: In one embodiment, the presence of anomalous material within tissue is detected by scanning a patient using magnetic resonance imaging (MRI) to obtain MRI data, identifying individual voxels of the MRI data, identifying multiple parameters of each voxel, and determining as to each voxel based upon the identified parameters the likelihood of tissue represented by the voxel containing anomalous material.

Abstract: Provided herein is a magnetic apparatus for collecting superparamagnetic particles from a subject. The superparamagnetic particles are previously injected into the subject and have ligands bound thereto that are specific for one or more non-cell biomarkers. In one embodiment, the superparamagnetic particles are injected into and retrieved from a cavity such as a joint cavity. These compositions and methods allow for the sequestration and removal of inflammatory mediators, as both a diagnostic of the local immune response and a therapeutic that can reduce inflammation in the local disease environment.

Abstract: In one embodiment, the presence of anomalous material within tissue is detected by scanning a patient using magnetic resonance imaging (MRI) to obtain MRI data, identifying individual voxels of the MRI data, identifying multiple parameters of each voxel, and determining as to each voxel based upon the identified parameters the likelihood of tissue represented by the voxel containing anomalous material.

Abstract: Provided herein is a magnetic apparatus for collecting superparamagnetic particles from a subject. The superparamagnetic particles are previously injected into the subject and have ligands bound thereto that are specific for one or more non-cell biomarkers. In one embodiment, the superparamagnetic particles are injected into and retrieved from a cavity such as a joint cavity. These compositions and methods allow for the sequestration and removal of inflammatory mediators, as both a diagnostic of the local immune response and a therapeutic that can reduce inflammation in the local disease environment.

Abstract: There is described a method of magnetically manipulating a cell in vivo which comprises the association of a magnetizable particle with a cell. More particularly, there is described a method of magnetically manipulating a cell which comprises the association of a magnetizable particle with a cell characterized in that the method comprises agonizing or antagonizing ion channels within a cell by the association of a magnetizable particle with a cell. There is also described the use of a magnetizable particle in a method of magnetically manipulating a cell in vivo and/or activating ion channels in vivo.

Abstract: A method of culturing tissue comprises growing tissue forming cells whilst subjecting the tissue forming cells to mechanical stresses which are generated magnetically.

Abstract: A spray deflecting joint of fluid conveying structures has a spray obstructing structure lying in the path of any fluid that might spray from the joint in any direction within a range of directions, wherein the spray obstructing structure is permanently attached to one of the fluid conveying structures, is shaped to reduce the momentum of liquid sprays and/or has a surface treatment to reduce the momentum of liquid sprays.

Abstract: A temperature-controlled actuator has a housing (12) with a proximal end and a moveable distal portion. A core-wire (16) extends along the housing, with its distal section anchored to the distal portion of the housing. The core-wire's distal section has an austenite state and a martensite state. The distal section moves the distal portion by transitioning between the austenite and martensite states in response to a temperature change along a thermometric section (22, 24) of the core-wire. A proximal section in mechanical communication with the core-wire's distal section transmits tension, provided by a tensioning element (20), to the distal section. The tensioning element, which is coupled to the proximal section of the core-wire, constantly applies a tensioning force to the core-wire.

Abstract: A method of culturing tissue comprises growing tissue forming cells whilst subjecting the tissue forming cells to mechanical stresses which are generated magnetically.

Abstract: The present invention describes a communications system that utilizes frequency division multiple access (FDMA), code division multiple access (CDMA), and time division multiple access (TDMA) techniques for providing efficient use of frequency spectrum while supporting a large number of transmitters/users (2-6). Many users of the communications system share a common frequency band, but each transmit their respective message bursts (50) at different and specific times via a TDMA technique. To facilitate synchronization of the TDMA technique, each transmitter of the system is synchronized to a common timing reference (1) thereby abating the need to maintain synchronization between the transmitters (2-6) and receivers (8-12) of the system.

Abstract: A method and apparatus for evoking epileptiform activity in patients with drug resistant epilepsy, as part of a presurgical evaluation procedure are disclosed. The apparatus includes a cranial helmet, for generating a DC magnetic field of a sufficient strength to evoke epileptiform activity, and means for localizing the regions of the patient's brain where said epileptiform activity has been evoked. In the preferred embodiment, the magnetic field strength varies between 1 milliTesla and 2 milliTesla, and is generated by two generally similar coils which are coaxially separated, and which are wound on corresponding thermoplastic members to form the helmet. The desired magnetic field strength is produced at about the middle of the distance between the two coils, in general registration with the hippocampus region of the brain. In an exemplary embodiment, the localizing means includes implantable Foramen Ovale electrodes for sensing the evoked and natural epileptic firings.