Abstract: Provided herein are novel 10Fn3 domains which specifically bind to PD-L1, as well as imaging agents based on the same for diagnostics.

Abstract: A radioisotope elution system is provided that has a component in a cabinet with a door equipped with an authentication system to open. The system may also have a user interface equipped with an authentication system. The radioisotope elution system has a dose calibrator equipped with a lifting mechanism for lifting and/or lowering the vial to be tested in the dose calibrator. The lifting mechanism may be controlled for preventing the vial from being lifted during a quality control test on a sample of eluate in the vial. This feature prevents a user from tampering and/or interfering with the vial while a quality control testing is in progress. There also is provided a radioisotope elution system with a scanning system for entering information about the radioisotope generator and/or the patient in the system. Systems ensuring that the eluant reservoir contains a saline solution are proposed.

Abstract: In an implementation, a software application on a computing device directs the device to extract audio data from a media file comprising the audio data and video data, generate a trim proposal based on analysis of speech in the audio data, and display a visualization of the trim proposal. A user may supply input comprising a selection of at least a portion of the visualization of the trim proposal, in response to which the device trims the media file.

Abstract: Disclosed are new configurations of a rubidium elution system that offer several advantages. The rubidium elution systems of the present disclosure comprise an assembly including a 82Sr/82Rb generator, an activity detector, a waste container, a pump, a sensor, a tubing circuit and at least one valve. The waste container is located in the lower section of the assembly. More particularly, the top surface of the waste container compartment is either below the top surface of the generator compartment, or the waste container is at the same elevation than the generator or below the pump.

Abstract: A radioisotope elution system is provided that has a component in a cabinet with a door equipped with an authentication system to open. The system may also have a user interface equipped with an authentication system. The radioisotope elution system has a dose calibrator equipped with a lifting mechanism for lifting and/or lowering the vial to be tested in the dose calibrator. The lifting mechanism may be controlled for preventing the vial from being lifted during a quality control test on a sample of eluate in the vial. This feature prevents a user from tampering and/or interfering with the vial while a quality control testing is in progress. There also is provided a radioisotope elution system with a scanning system for entering information about the radioisotope generator and/or the patient in the system. Systems ensuring that the eluant reservoir contains a saline solution are proposed.

Abstract: Disclosed herein are rubidium elution systems comprising a primary assembly including a 82Sr/82Rb generator, an activity detector, a waste container, a pump system, a sensor, a tubing circuit, at least one valve, and a computer; and a dose calibrator outside the primary assembly. The system may have an interface for configuring the dose calibrator, and a locking means for preventing access to the interface and reconfigurations of its parameters. Moreover, the dose calibrator may be in electronic communication with the computer of the system. Furthermore, the electronic communication can be embodied with an electronic cable having a breakaway connector. Also, the dose calibrator may be positioned on a mobile platform.

Abstract: Real-time busyness information is for a public place is computed in a privacy-sensitive way, and provided for display in relation to historical busyness information. An aggregate amount of real-time location information available for a particular public place is measured (410), and used to determine (420) whether the public place is privacy-qualified. If the public place is privacy-qualified, real-time busyness information is computed (440) for the public place based on the real-time location information. Further, it is determined (450) whether the computed real-time busyness information is accuracy-qualified, based on a comparison of the real-time busyness information to historical busyness information. If both qualifications are met, the real-time busyness information is output (470) for display or to another application.

Abstract: A radioisotope elution system is provided, that has at least a component comprised in a cabinet and accessible via a door equipped with an authentication system to ensure safety. The system may also have a user interface equipped with an authentication system. It is also provided a radioisotope elution system that has a dose calibrator equipped with a lifting mechanism for lifting and/or lowering the vial to be tested in the dose calibrator. Advantageously, the lifting mechanism may be controlled for preventing the vial from being lifted during a quality control test on a sample of eluate in the vial. This feature prevents a user from tampering and/or interfering with the vial while a quality control testing is in progress. In another feature, there is provided a radioisotope elution system with a scanning system for entering information about the radioisotope generator and/or the patient in the system. Systems ensuring that the eluant reservoir contains a saline solution are proposed.

Abstract: A radioisotope elution system is provided. The radioisotope elution system may comprise a controller that is configured to calculate the available amount of daughter radioisotope at any time during establishment of the equilibrium for decay of the parent radioisotope into its daughter radioisotope. The radioisotope elution system may comprise a controller that is configured to schedule various patient infusions planned for the next following days and weeks in accordance with the available amount of daughter radioisotope on each day. The elution system may also comprise a controller that is connected to the imaging software of a radioisotope imaging device, where the radioisotope imaging device is arranged for imaging the patient or a region of the patient; and the controller is configured to start an image acquisition at a predetermined time.

Abstract: In an implementation, a software application on a computing device directs the device to extract audio data from a media file comprising the audio data and video data, generate a trim proposal based on analysis of speech in the audio data, and display a visualization of the trim proposal. A user may supply input comprising a selection of at least a portion of the visualization of the trim proposal, in response to which the device trims the media file.

Abstract: In the present disclosure, a collaborative workspace fosters content creation between users in a synchronous and/or asynchronous manner by enabling automatic generation and management of collaborative media objects that automatically combine content from a plurality of users into a single media object. This is extremely beneficial in technical scenarios where users are creating projects, assignments, presentations, etc., by removing the need for users to manually stitch together and combine content to create a final product. For example, the collaborative workspace is adapted for a video discussion application/service, where users create one or more video clips (e.g., video feeds, live video feeds) in response to a posted topic. In at least one instance, a collaborative workspace for a video discussion application/service may be integrated to display within another type of application/service. However, the present disclosure is extensible to work with any type of application/service and any content type.

Abstract: A radioisotope elution system is provided. The radioisotope elution system may comprise a controller that is configured to calculate the available amount of daughter radioisotope at any time during establishment of the equilibrium for decay of the parent radioisotope into its daughter radioisotope. The radioisotope elution system may comprise a controller that is configured to schedule various patient infusions planned for the next following days and weeks in accordance with the available amount of daughter radioisotope on each day. The elution system may also comprise a controller that is connected to the imaging software of a radioisotope imaging device, where the radioisotope imaging device is arranged for imaging the patient or a region of the patient; and the controller is configured to start an image acquisition at a predetermined time.

Abstract: Real-time busyness information is for a public place is computed in a privacy-sensitive way, and provided for display in relation to historical busyness information. An aggregate amount of real-time location information available for a particular public place is measured (410), and used to determine (420) whether the public place is privacy-qualified. If the public place is privacy-qualified, real-time busyness information is computed (440) for the public place based on the real-time location information. Further, it is determined (450) whether the computed real-time busyness information is accuracy-qualified, based on a comparison of the real-time busyness information to historical busyness information. If both qualifications are met, the real-time busyness information is output (470) for display or to another application.

Abstract: The present technology provides compounds, as well as compositions including such compounds, useful for imaging and/or treatment of a non-small cell lung cancer, small cell carcinoma of the lung, bladder cancer, colon cancer, gallbladder cancer, pancreatic cancer, esophageal cancer, melanoma, liver cancer, primary gastric adenocarcinoma, primary colorectal adenocarcinoma, renal cell carcinoma, prostate cancer, a neuroendocrine tumor, a pituitary tumor, a vasoactive intestinal peptide-secreting tumor, a glioma, breast cancer, an adrenal cortical cancer, a cervical carcinoma, a vulvar carcinoma, an endometrial carcinoma, a primary ovarian carcinoma, a metastatic ovarian carcinoma, and/or a metastatic cancer.

Abstract: In the present disclosure, a collaborative workspace fosters content creation between users in a synchronous and/or asynchronous manner by enabling automatic generation and management of collaborative media objects that automatically combine content from a plurality of users into a single media object. This is extremely beneficial in technical scenarios where users are creating projects, assignments, presentations, etc., by removing the need for users to manually stitch together and combine content to create a final product. For example, the collaborative workspace is adapted for a video discussion application/service, where users create one or more video clips (e.g., video feeds, live video feeds) in response to a posted topic. In at least one instance, a collaborative workspace for a video discussion application/service may be integrated to display within another type of application/service. However, the present disclosure is extensible to work with any type of application/service and any content type.

Abstract: In the present disclosure, a collaborative workspace fosters content creation between users in a synchronous and/or asynchronous manner by enabling automatic generation and management of collaborative media objects that automatically combine content from a plurality of users into a single media object. This is extremely beneficial in technical scenarios where users are creating projects, assignments, presentations, etc., by removing the need for users to manually stitch together and combine content to create a final product. For example, the collaborative workspace is adapted for a video discussion application/service, where users create one or more video clips (e.g., video feeds, live video feeds) in response to a posted topic. In at least one instance, a collaborative workspace for a video discussion application/service may be integrated to display within another type of application/service. However, the present disclosure is extensible to work with any type of application/service and any content type.

Abstract: In the present disclosure, a collaborative workspace fosters content creation between users in a synchronous and/or asynchronous manner by enabling automatic generation and management of collaborative media objects that automatically combine content from a plurality of users into a single media object. To improve processing efficiency and user productivity, the present disclosure further provides processing that applies trained artificial intelligence (AI) processing that is adapted to automatically generate representations of data insights for management of a collaborative media object within the collaborative workspace. Data insights are generated pertaining to feature management of an exemplary application/service (e.g., video discussion application/service) including features for generating and managing a collaborative media object. Signal data associated with users of a collaborative session (e.g., within a collaborative workspace) is detected and analyzed.

Abstract: Real-time busyness information is for a public place is computed in a privacy-sensitive way, and provided for display in relation to historical busyness information. An aggregate amount of real-time location information available for a particular public place is measured (410), and used to determine (420) whether the public place is privacy-qualified. If the public place is privacy-qualified, real-time busyness information is computed (440) for the public place based on the real-time location information. Further, it is determined (450) whether the computed real-time busyness information is accuracy-qualified, based on a comparison of the real-time busyness information to historical busyness information. If both qualifications are met, the real-time busyness information is output (470) for display or to another application.

Abstract: In the present disclosure, a collaborative workspace fosters content creation between users in a synchronous and/or asynchronous manner by enabling automatic generation and management of collaborative media objects that automatically combine content from a plurality of users into a single media object. This is extremely beneficial in technical scenarios where users are creating projects, assignments, presentations, etc., by removing the need for users to manually stitch together and combine content to create a final product. For example, the collaborative workspace is adapted for a video discussion application/service, where users create one or more video clips (e.g., video feeds, live video feeds) in response to a posted topic. In at least one instance, a collaborative workspace for a video discussion application/service may be integrated to display within another type of application/service. However, the present disclosure is extensible to work with any type of application/service and any content type.

Abstract: In the present disclosure, a collaborative workspace fosters content creation between users in a synchronous and/or asynchronous manner by enabling automatic generation and management of collaborative media objects that automatically combine content from a plurality of users into a single media object. To improve processing efficiency and user productivity, the present disclosure further provides processing that applies trained artificial intelligence (AI) processing that is adapted to automatically generate representations of data insights for management of a collaborative media object within the collaborative workspace. Data insights are generated pertaining to feature management of an exemplary application/service (e.g., video discussion application/service) including features for generating and managing a collaborative media object. Signal data associated with users of a collaborative session (e.g., within a collaborative workspace) is detected and analyzed.