Abstract: A process is described for filtration of fluids, particularly of heterodisperse fluids like beer, in which a cleaning cycle of the MF modules is always carried out when the transmembrane pressure exceeds a pre-set pressure which has been selected to be equal to the optimal trans-membrane pressure for the particular fluid to be filtered as regards its analytical appearance. In beer filtration this value is preferably set at 1.5 bar. The microfiltration facility is equipped with numerous MF modules 5, arrayed in series and parallel; with a device for cleansing the MF modules 5; and with a measuring device 3 for recording trans-membrane pressure, attached to a control device 7, which, upon attaining the pre-set trans-membrane pressure, interrupts the filtration process and starts a cleansing cycle going.