Patents by Inventor Paul E. Aldrich

Paul E. Aldrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Negative photoresists containing aminoacrylate salts
    Patent number: 5399460
    Abstract: Negative photoresists, and electronic devices comprising dielectric polyimide films resulting from such photoresists. The Photoresists comprise polyamic acids, which have been neutralized with tertiary amines containing double bonds of the acrylic family, the amines including acrylamines, alkylacrylamines such as for example methacrylamines, ethacrylamines, and the like. Also methods of making such amines in high purity.
    Type: Grant
    Filed: December 4, 1991
    Date of Patent: March 21, 1995
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul E. Aldrich, Philip Manos, Allan E. Nader
  • 2-amino-1, 4-dihydropyridine derivatives with calcium agonist and alpha.sub. -antagonist activity
    Patent number: 5314887
    Abstract: There are provided novel 1,4-dihydropyridine compounds possessing both calcium agonist and alpha.sub.1 -antagonist activity useful for treating congestive heart failure, pharmaceutical compositions containing them and methods of using these compounds to treat congestive heart failure in a mammal.
    Type: Grant
    Filed: October 30, 1992
    Date of Patent: May 24, 1994
    Assignee: The Du Pont Merck Pharmaceutical Company
    Inventors: Paul E. Aldrich, Richard A. Earl, Philip Ma
  • 2-amino-1,4-dihydropyridine derivatives with calcium agonist and alpha.sub.1 -antagonist activity
    Patent number: 5166148
    Abstract: There are provided novel 1,4-dihydropyridine compounds possessing both calcium agonist and alpha.sub.1 -antagonist activity useful for treating congestive heart failure, pharmaceutical compositions containing them and methods of using these compounds to treat congestive heart failure in a mammal.
    Type: Grant
    Filed: July 9, 1990
    Date of Patent: November 24, 1992
    Assignee: The Du Pont Merck Pharmaceutical Company
    Inventors: Paul E. Aldrich, Richard A. Earl, Philip Ma
  • Tetrazole intermediates to antihypertensive compounds
    Patent number: 4874867
    Abstract: Tetrazole intermediates useful to prepare antihypertensive compounds described in coassigned application U.S. Ser. No. 884,920, filed July 11, 1986, are described, these tetrazoles have the formula: ##STR1## wherein X.sup.1 and X.sup.2 are as described in the specification.
    Type: Grant
    Filed: November 23, 1988
    Date of Patent: October 17, 1989
    Assignee: E. I. Du Pont De Nemours and Company
    Inventors: Paul E. Aldrich, John Jonas V. Duncia, Michael E. Pierce
  • Tetrazole intermediates to antihypertensive compounds
    Patent number: 4870186
    Abstract: Tetrazole intermediates useful to prepare antihypertensive compounds described in coassigned application U.S. Ser. No. 884,920, filed July 11, 1986, are described, these tetrazoles have the formula: ##STR1## wherein X.sup.1 and X.sup.2 are as described in the specification.
    Type: Grant
    Filed: November 23, 1988
    Date of Patent: September 26, 1989
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul E. Aldrich, John J. V. Duncia, Michael E. Pierce
  • Tetrazole intermediates to antihypertensive compounds
    Patent number: 4820843
    Abstract: Tetrazole intermediates useful to prepare antihypertensive compounds described in coassigned application U.S. Ser. No. 884,920, filed July 11, 1986, are described, these tetrazoles have the formula: ##STR1## wherein X.sup.1 and X.sup.2 are as described in the specification.
    Type: Grant
    Filed: May 22, 1987
    Date of Patent: April 11, 1989
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul E. Aldrich, John Jonas V. Duncia, Michael E. Pierce
  • Antihypertensive polyhalohydroxylisopropyl phenylalkanoic and phenylalkenoic acids, amides and esters and intermediates thereto
    Patent number: 4727180
    Abstract: Polyhalohydroxyisopropyl phenylalkanoic and phenylalkenoic acids, amides, and esters, such as methyl 2-methoxy-4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]benzenepro panoate, are useful as antihypertensive agents.
    Type: Grant
    Filed: January 4, 1985
    Date of Patent: February 23, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul E. Aldrich, Gilbert H. Berezin
  • Antihypertensive polyfluoroisopropyl tricyclic carbostyrils
    Patent number: 4322417
    Abstract: Polyfluorohydroxyisopropyl tricyclic carbostyrils, such as 2,3-dihydro-7-methyl-9-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl ]-5H-[1,4]thiazino[2,3,4-ij]-quinolin-5-one, useful as antihypertensive agents.
    Type: Grant
    Filed: December 22, 1977
    Date of Patent: March 30, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul E. Aldrich, Gilbert H. Berezin
  • Polyfluorohydroxyisopropyl-heterocyclic compounds
    Patent number: 4251659
    Abstract: Polyfluorohydroxyisopropyl: -indolines, -tetrahydroquinolines, and -benzazepines, such a .alpha.,.alpha.-bis(trifluoromethyl)-1,2,3,4-tetrahydroquinoline-6-methano l, useful as intermediates for antihypertensives.
    Type: Grant
    Filed: December 22, 1977
    Date of Patent: February 17, 1981
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul E. Aldrich, Gilbert H. Berezin
  • Antihypertensive polyfluorohydroxyisopropyl bicyclic and tricyclic carbostyrils
    Patent number: 4218448
    Abstract: Polyfluorohydroxyisopropyl bicyclic and tricyclic carbostyrils, such as 1,2-dihydro-8-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-6-methy l-4H-pyrrolo-[3,2,1-ij]quinolin-7-one, useful as antihypertensive agents.
    Type: Grant
    Filed: December 22, 1977
    Date of Patent: August 19, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul E. Aldrich, Gilbert H. Berezin
  • 1-Tertiary-alkyl-3-(substituted cyclohexenyl)ureas as antihypertensive agents
    Patent number: 4002767
    Abstract: 1-Tertiary-alkyl-3-(substituted cyclohexenyl)ureas that exhibit antihypertensive activity in warm-blooded animals. A representative compound is 1-tert-butyl-3-(3-oxo-1-cyclohexen-1-yl)urea.
    Type: Grant
    Filed: March 11, 1975
    Date of Patent: January 11, 1977
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul E. Aldrich, Gilbert H. Berezin, Bruce I. Dittmar