Patents by Inventor Paul E. Chirico

Paul E. Chirico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11925723
    Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: March 12, 2024
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Paul E. Chirico, Bohdan Wolodymyr Chopko, John Barr, Robert Vincent McCormick, Julie Lucero, Jason A. Jegge
  • Publication number: 20220133376
    Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
    Type: Application
    Filed: January 18, 2022
    Publication date: May 5, 2022
    Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO
  • Patent number: 11224471
    Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: January 18, 2022
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico
  • Publication number: 20210283303
    Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.
    Type: Application
    Filed: June 1, 2021
    Publication date: September 16, 2021
    Inventors: Houdin DEHNAD, Paul E. CHIRICO, Bohdan Wolodymyr CHOPKO, John BARR, Robert Vincent McCORMICK, Julie LUCERO, Jason A. JEGGE
  • Patent number: 11020508
    Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: June 1, 2021
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Paul E. Chirico, Bohdan Wolodymyr Chopko, John Barr, Robert Vincent McCormick, Julie Lucero, Jason A. Jegge
  • Publication number: 20190357954
    Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 28, 2019
    Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO
  • Publication number: 20190247538
    Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.
    Type: Application
    Filed: April 22, 2019
    Publication date: August 15, 2019
    Inventors: Houdin DEHNAD, Paul E. CHIRICO, Bohdan Wolodymyr CHOPKO, John BARR, Robert Vincent McCORMICK, Julie LUCERO, Jason A. JEGGE
  • Patent number: 10368929
    Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: August 6, 2019
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico
  • Patent number: 10265435
    Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: April 23, 2019
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Paul E. Chirico, Bohdan Wolodymyr Chopko, John Barr, Robert Vincent McCormick, Julie Lucero, Jason A. Jegge
  • Publication number: 20180296262
    Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
    Type: Application
    Filed: June 21, 2018
    Publication date: October 18, 2018
    Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO
  • Patent number: 10004548
    Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: June 26, 2018
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico
  • Publication number: 20180093013
    Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.
    Type: Application
    Filed: November 21, 2017
    Publication date: April 5, 2018
    Inventors: Houdin DEHNAD, Paul E. CHIRICO, Bohdan Wolodymyr CHOPKO, John BARR, Robert Vincent MC CORMICK, Julie LUCERO, Jason A. JEGGE
  • Patent number: 9889284
    Abstract: Silver and/or zinc ion releasing implants, systems and method of operating, inserting and activating/inactivating them are described. In some variations the implant is configured as a bone implant that includes a bone-screw or intramedullary rod like body configured to receive a treatment cartridge having a plurality of ion-releasing members configured as an anode that can controllably engage with a catheter to turn galvanic release of ions on/off as desired. These devices may be configured to release silver ions (and/or zinc ions) above a predetermined level for a predetermined period of time and may maintain a concentration of ions over a relatively large volume of tissue. The ion-releasing members may be configured to reduce or prevent implant movement.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: February 13, 2018
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico, Robert Vincent McCormick
  • Patent number: 9821094
    Abstract: Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: November 21, 2017
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Paul E. Chirico, Bohdan Wolodymyr Chopko, John Barr, Robert Vincent McCormick, Julie Lucero, Jason A. Jegge
  • Publication number: 20170312399
    Abstract: Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate (including, but not limited to absorbable/resorbable substrates) so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.
    Type: Application
    Filed: November 13, 2015
    Publication date: November 2, 2017
    Inventors: Houdin DEHNAD, Julie LUCERO, Paul E. CHIRICO, Jason A. JEGGE, Thomas Lee GUTSHALL
  • Patent number: 9789298
    Abstract: Silver and/or zinc ion releasing implants, systems and method of operating, inserting and activating/inactivating them are described. In some variations the implant is configured as a bone implant that includes a bone-screw or intramedullary rod like body configured to receive a treatment cartridge having a plurality of ion-releasing members configured as an anode that can controllably engage with a catheter to turn galvanic release of ions on/off as desired. These devices may be configured to release silver ions (and/or zinc ions) above a predetermined level for a predetermined period of time and may maintain a concentration of ions over a relatively large volume of tissue. The ion-releasing members may be configured to reduce or prevent implant movement.
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: October 17, 2017
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico, Robert Vincent McCormick
  • Publication number: 20170014607
    Abstract: Silver and/or zinc ion releasing implants, systems and method of operating, inserting and activating/inactivating them are described. In some variations the implant is configured as a bone implant that includes a bone-screw or intramedullary rod like body configured to receive a treatment cartridge having a plurality of ion-releasing members configured as an anode that can controllably engage with a catheter to turn galvanic release of ions on/off as desired. These devices may be configured to release silver ions (and/or zinc ions) above a predetermined level for a predetermined period of time and may maintain a concentration of ions over a relatively large volume of tissue. The ion-releasing members may be configured to reduce or prevent implant movement.
    Type: Application
    Filed: July 16, 2015
    Publication date: January 19, 2017
    Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO, Robert Vincent MC CORMICK
  • Patent number: 9452242
    Abstract: Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate (including, but not limited to absorbable/resorbable substrates) so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: September 27, 2016
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Julie Lucero, Paul E. Chirico, Jason A. Jegge, Thomas Lee Gutshall
  • Publication number: 20160157907
    Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
    Type: Application
    Filed: February 1, 2016
    Publication date: June 9, 2016
    Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO
  • Publication number: 20160136335
    Abstract: Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate (including, but not limited to absorbable/resorbable substrates) so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.
    Type: Application
    Filed: July 22, 2015
    Publication date: May 19, 2016
    Inventors: Houdin DEHNAD, Julie LUCERO, Paul E. CHIRICO, Jason A. JEGGE, Thomas Lee GUTSHALL