Patents by Inventor Paul E. Chirico
Paul E. Chirico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11925723Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.Type: GrantFiled: June 1, 2021Date of Patent: March 12, 2024Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Paul E. Chirico, Bohdan Wolodymyr Chopko, John Barr, Robert Vincent McCormick, Julie Lucero, Jason A. Jegge
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Publication number: 20220133376Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.Type: ApplicationFiled: January 18, 2022Publication date: May 5, 2022Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO
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Patent number: 11224471Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.Type: GrantFiled: August 5, 2019Date of Patent: January 18, 2022Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico
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Publication number: 20210283303Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.Type: ApplicationFiled: June 1, 2021Publication date: September 16, 2021Inventors: Houdin DEHNAD, Paul E. CHIRICO, Bohdan Wolodymyr CHOPKO, John BARR, Robert Vincent McCORMICK, Julie LUCERO, Jason A. JEGGE
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Patent number: 11020508Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.Type: GrantFiled: April 22, 2019Date of Patent: June 1, 2021Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Paul E. Chirico, Bohdan Wolodymyr Chopko, John Barr, Robert Vincent McCormick, Julie Lucero, Jason A. Jegge
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Publication number: 20190357954Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.Type: ApplicationFiled: August 5, 2019Publication date: November 28, 2019Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO
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Publication number: 20190247538Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.Type: ApplicationFiled: April 22, 2019Publication date: August 15, 2019Inventors: Houdin DEHNAD, Paul E. CHIRICO, Bohdan Wolodymyr CHOPKO, John BARR, Robert Vincent McCORMICK, Julie LUCERO, Jason A. JEGGE
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Patent number: 10368929Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.Type: GrantFiled: June 21, 2018Date of Patent: August 6, 2019Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico
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Patent number: 10265435Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.Type: GrantFiled: November 21, 2017Date of Patent: April 23, 2019Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Paul E. Chirico, Bohdan Wolodymyr Chopko, John Barr, Robert Vincent McCormick, Julie Lucero, Jason A. Jegge
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Publication number: 20180296262Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.Type: ApplicationFiled: June 21, 2018Publication date: October 18, 2018Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO
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Patent number: 10004548Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.Type: GrantFiled: February 1, 2016Date of Patent: June 26, 2018Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico
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Publication number: 20180093013Abstract: Antimicrobial metal ion coatings and implants including them. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, rhodium, manganese, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal. The implant may be configured as an implant such as a bone-screw or intramedullary rod-like body configured to receive a treatment cartridge having a coating as described.Type: ApplicationFiled: November 21, 2017Publication date: April 5, 2018Inventors: Houdin DEHNAD, Paul E. CHIRICO, Bohdan Wolodymyr CHOPKO, John BARR, Robert Vincent MC CORMICK, Julie LUCERO, Jason A. JEGGE
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Patent number: 9889284Abstract: Silver and/or zinc ion releasing implants, systems and method of operating, inserting and activating/inactivating them are described. In some variations the implant is configured as a bone implant that includes a bone-screw or intramedullary rod like body configured to receive a treatment cartridge having a plurality of ion-releasing members configured as an anode that can controllably engage with a catheter to turn galvanic release of ions on/off as desired. These devices may be configured to release silver ions (and/or zinc ions) above a predetermined level for a predetermined period of time and may maintain a concentration of ions over a relatively large volume of tissue. The ion-releasing members may be configured to reduce or prevent implant movement.Type: GrantFiled: July 16, 2015Date of Patent: February 13, 2018Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico, Robert Vincent McCormick
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Patent number: 9821094Abstract: Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.Type: GrantFiled: August 24, 2015Date of Patent: November 21, 2017Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Paul E. Chirico, Bohdan Wolodymyr Chopko, John Barr, Robert Vincent McCormick, Julie Lucero, Jason A. Jegge
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Publication number: 20170312399Abstract: Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate (including, but not limited to absorbable/resorbable substrates) so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.Type: ApplicationFiled: November 13, 2015Publication date: November 2, 2017Inventors: Houdin DEHNAD, Julie LUCERO, Paul E. CHIRICO, Jason A. JEGGE, Thomas Lee GUTSHALL
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Patent number: 9789298Abstract: Silver and/or zinc ion releasing implants, systems and method of operating, inserting and activating/inactivating them are described. In some variations the implant is configured as a bone implant that includes a bone-screw or intramedullary rod like body configured to receive a treatment cartridge having a plurality of ion-releasing members configured as an anode that can controllably engage with a catheter to turn galvanic release of ions on/off as desired. These devices may be configured to release silver ions (and/or zinc ions) above a predetermined level for a predetermined period of time and may maintain a concentration of ions over a relatively large volume of tissue. The ion-releasing members may be configured to reduce or prevent implant movement.Type: GrantFiled: June 10, 2014Date of Patent: October 17, 2017Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico, Robert Vincent McCormick
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Publication number: 20170014607Abstract: Silver and/or zinc ion releasing implants, systems and method of operating, inserting and activating/inactivating them are described. In some variations the implant is configured as a bone implant that includes a bone-screw or intramedullary rod like body configured to receive a treatment cartridge having a plurality of ion-releasing members configured as an anode that can controllably engage with a catheter to turn galvanic release of ions on/off as desired. These devices may be configured to release silver ions (and/or zinc ions) above a predetermined level for a predetermined period of time and may maintain a concentration of ions over a relatively large volume of tissue. The ion-releasing members may be configured to reduce or prevent implant movement.Type: ApplicationFiled: July 16, 2015Publication date: January 19, 2017Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO, Robert Vincent MC CORMICK
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Patent number: 9452242Abstract: Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate (including, but not limited to absorbable/resorbable substrates) so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.Type: GrantFiled: July 22, 2015Date of Patent: September 27, 2016Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Julie Lucero, Paul E. Chirico, Jason A. Jegge, Thomas Lee Gutshall
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Publication number: 20160157907Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.Type: ApplicationFiled: February 1, 2016Publication date: June 9, 2016Inventors: Houdin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO
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Publication number: 20160136335Abstract: Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate (including, but not limited to absorbable/resorbable substrates) so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.Type: ApplicationFiled: July 22, 2015Publication date: May 19, 2016Inventors: Houdin DEHNAD, Julie LUCERO, Paul E. CHIRICO, Jason A. JEGGE, Thomas Lee GUTSHALL