Patents by Inventor Paul E. Hessler

Paul E. Hessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Essential bacteria genes and genome scanning in Haemophilus influenzae for the identification of 'essential genes'
    Publication number: 20030021813
    Abstract: Essential bacteria genes and a method for identifying ‘essential genes’ (i.e., genes which are essential to a bacterium's survival) using an in vitro transposition system, a small (975 bp) insertional element containing an antibiotic resistance cassette and mapping these inserts relative to the deduced open reading frames of H. influenzae by PCR and Southern analysis.
    Type: Application
    Filed: September 30, 2002
    Publication date: January 30, 2003
    Inventors: Linda E. Chovan, Paul E. Hessler, Karl A. Reich
  • Methods and compositions for enhancing erythromycin production
    Patent number: 5976836
    Abstract: The present invention provides isolated and purified polypeptides that increase antibiotic production, polynucleotides that encode those polypeptides, expression vectors containing those polynucleotides, host cells transformed with those expression vectors, a process of making the polypeptides using those polynucleotides and vectors, and processes using those polypeptides and polynucleotides.
    Type: Grant
    Filed: May 7, 1997
    Date of Patent: November 2, 1999
    Assignee: FermaLogic, Inc.
    Inventors: J. Mark Weber, Paul E. Hessler, Peter E. Larsen, Minh B. Luu
  • Process of preparing genistein
    Patent number: 5554519
    Abstract: The present invention provides a process of preparing the isoflavone genistein. Genistein is prepared by fermenting the bacteria Saccharopolyspora erythraea in the presence of a soy-based substrate. A process of recovering genistein from a bacterial fermentation medium using alkaline, organic solvent extraction is also provided.
    Type: Grant
    Filed: August 7, 1995
    Date of Patent: September 10, 1996
    Assignee: FermaLogic, Inc.
    Inventors: J. Mark Weber, Andreas Constantinou, Paul E. Hessler