Patents by Inventor Paul E. Juniewicz

Paul E. Juniewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating a tumor
    Patent number: 6319923
    Abstract: In accordance with the present invention there is provided a method of treating a mammal having a solid tumor, the method comprising: a) administering to the mammal an effective amount of 3-ainino-1,2,4-benzotriazine 1,4-dioxide; b) administering to the mammal an effective amount of paclitaxel; and c) administering to the mammal an effective amount of a platinum complex. The method provides unexpected synergistic efficacy. The invention further provides a kit for treatment of a mammalian tumor comprising 3-amino-1,2,-benzotriazine 1,4-dioxide, paclitaxel and a platinum complex.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: November 20, 2001
    Assignee: Sanofi-Synthelabo Inc.
    Inventors: Daniel L. Dexter, Paul E. Juniewicz, James B. Rake, Daniel D. Von Hoff
  • Method of treating a tumor
    Patent number: 6063780
    Abstract: In accordance with the present invention there is provided a method of treating a mammal having a solid tumor, the method comprising:a) administering to the mammal an effective amount of 3-amino-1,2,4-benzotriazine 1,4-dioxide;b) administering to the mammal an effective amount of paclitaxel; andc) administering to the mammal an effective amount of a platinum complex.The method provides unexpected synergistic efficacy. The invention further provides a kit for treatment of a mammalian tumor comprising 3-amino-1,2,-benzotriazine 1,4-dioxide, paclitaxel and a platinum complex.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: May 16, 2000
    Assignee: Sanofi-Synthelabo Inc.
    Inventors: Daniel L. Dexter, Paul E. Juniewicz, James B. Rake, Daniel D. Von Hoff
  • Win 49596-finasteride method of use and compositions
    Patent number: 5175155
    Abstract: The method of use of a combination of the antiandrogen (5.alpha.,17.alpha.)-1'-(methylsulfonyl)-1'H-pregn-20-yno[3,2-c]pyrazol-17 -ol (Win 49596) and the 5.alpha.-reductase inhibitor (5.alpha.,17.beta.)-N-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carb oxamide (finasteride) for treating prostate disease in a male mammal and pharmaceutical compositions thereof are disclosed.
    Type: Grant
    Filed: October 7, 1991
    Date of Patent: December 29, 1992
    Assignee: Sterling Winthrop Inc.
    Inventors: Paul E. Juniewicz, Bruce M. Berger