Patents by Inventor Paul E. Stephens

Paul E. Stephens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIVALENT FZD4, WNT CO-RECEPTOR, AND VEGF RECEPTOR MOLECULES AND USES THEREOF
    Publication number: 20260092109
    Abstract: Herein are multivalent antibody binding molecules that activate a Wnt/?-catenin signaling pathway comprising a FZD4 receptor binding domain, an LRP5 co-receptor binding domain, and a VEGF binding domain. Also described herein are nucleic acids and vectors encoding said molecules and methods for their use.
    Type: Application
    Filed: September 4, 2025
    Publication date: April 2, 2026
    Applicants: EyeBiotech Limited, Merck Sharp & Dohme LLC
    Inventors: Paul E. Stephens, Michael John Davies, Yin Shan Eric Ng, Masahisa Handa, Alexander V. Loktev
  • MULTIVALENT FZD4, WNT CO-RECEPTOR, AND VEGF BINDING MOLECULES AND USES THEREOF
    Publication number: 20260092125
    Abstract: Herein are multivalent antibody binding molecules that activate a Wnt/?-catenin signaling pathway comprising a FZD4 receptor binding domain, an LRP5 co-receptor binding domain, and a VEGF binding domain. Also described herein are nucleic acids and vectors encoding said molecules and methods for their use.
    Type: Application
    Filed: September 4, 2025
    Publication date: April 2, 2026
    Applicants: EyeBiotech Limited, Merck Sharp & Dohme LLC
    Inventors: Paul E. Stephens, Michael John Davies, Yin Shan Eric Ng, Masahisa Handa, Alexander V. Loktev
  • MULTIVALENT FZD4, WNT CO-RECEPTOR, AND VEGF RECEPTOR MOLECULES AND USES THEREOF
    Publication number: 20260070966
    Abstract: Herein are multivalent antibody binding molecules that activate a Wnt/?-catenin signaling pathway comprising a FZD4 receptor binding domain, an LRP5 co-receptor binding domain, and a VEGF binding domain. Also described herein are nucleic acids and vectors encoding said molecules and methods for their use.
    Type: Application
    Filed: September 4, 2025
    Publication date: March 12, 2026
    Applicants: EyeBiotech Limited, Merck Sharp & Dohme LLC
    Inventors: Paul E. Stephens, Michael John Davies, Yin Shan Eric Ng, Masahisa Handa, Alexander V. Loktev
  • Apparatus and method for efficiently allocating memory to reconstruct a data structure
    Patent number: 5412805
    Abstract: A method, system and process for enhancing a database server by improving memory allocation and memory copying during the process of reconstructing a data structure.
    Type: Grant
    Filed: August 3, 1992
    Date of Patent: May 2, 1995
    Assignee: International Business Machines Corporation
    Inventors: Lloyd E. Jordan, II, Shaw-Ben Shi, Martin J. Sirkin, Paul E. Stephens