Patents by Inventor Paul Edward Aldrich

Paul Edward Aldrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1N-alkyl-n-arylpyrimidinamines and derivatives thereof
    Patent number: 6342503
    Abstract: The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppression, Alzheimer'disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula: wherein R1, R3, R4, R5, Z, Y, V, X, X′, J, K, L, and M are as defined herein.
    Type: Grant
    Filed: January 7, 1998
    Date of Patent: January 29, 2002
    Assignee: DuPont Pharmaceuticals Company
    Inventors: Paul Edward Aldrich, Argyrios Georgios Arvanitis, Robert Scott Cheeseman, Robert John Chorvat, Thomas Eugene Christos, Paul Joseph Gilligan, Dimitri Emil Grigoriadis, Carl Nicholas Hodge, Paul John Krenitsky, Everett Latham Scholfield, Sang William Tam, Zelda Rakowitz Wasserman
  • 1N-alkyl-N-arylpyrimidinamines and derivatives thereof
    Patent number: 6107301
    Abstract: The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppression, Alzheimer's disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula: ##STR1## wherein R.sup.1, R.sup.3, R.sup.4, R.sup.5, Z, Y, V, X, X', J, K, L, and M are as defined herein.
    Type: Grant
    Filed: August 5, 1997
    Date of Patent: August 22, 2000
    Assignee: Dupont Pharmaceuticals Company
    Inventors: Paul Edward Aldrich, Argyrios Georgios Arvanitis, Rajagopal Bakthavatchalam, James Peter Beck, Robert Scott Cheeseman, Robert John Chorvat, Paul Joseph Gilligan, Carl Nicholas Hodge, Zelda Rakowitz Wasserman
  • Antihypertensive hexafluorohydroxyisopropyl benzazepines and benzazocines
    Patent number: 4107303
    Abstract: Hexafluorohydroxyisopropyl: -tetrahydroquinolines, -benzazepines, and -benzazocines, such as 2,3,4,5-tetrahydro-1-(1-oxopropyl)-.alpha.,.alpha.-bis(trifluoromethyl)-1H -1-benzazepine-7-methanol useful as antihypertensives.
    Type: Grant
    Filed: June 24, 1976
    Date of Patent: August 15, 1978
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul Edward Aldrich, Gilbert Harvey Berezin
  • 1-Tertiary-alkyl-3-(substituted thienyl)ureas and 1-tertiary-alkyl-3-(substituted thietyl)ureas as antihypertensive agents
    Patent number: 4070479
    Abstract: This invention relates to a class of 1-tertiary-alkyl-3-(substituted thienyl)ureas and 1-tertiary-alkyl-3-(substituted thietyl)ureas that exhibit antihypertensive activity in warm-blooded animals. Representative compounds are 1-tert-butyl-3-(4,5-dihydro-3-thienyl)urea S,S-dioxide and 1-tert-butyl-3-(3-thietyl)urea S,S-dioxide.
    Type: Grant
    Filed: November 18, 1976
    Date of Patent: January 24, 1978
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul Edward Aldrich, Gilbert Harvey Berezin, Bruce Ivor Dittmar
  • 1-Tertiary-alkyl-3-(substituted thienyl)ureas and 1-tertiary-alkyl-3-(substituted thietyl)ureas as antihypertensive agents
    Patent number: 4009847
    Abstract: This invention relates to a class of 1-tertiary-alkyl-3-(substituted thienyl)ureas and 1-tertiary-alkyl-3-(substituted thietyl)ureas that exhibit antihypertensive activity in warm-blooded animals. Representative compounds are 1-tert-butyl-3-(4,5-dihydro-3-thienyl)urea S,S-dioxide and 1-tert-butyl-3-(3-thiethyl)urea S,S-dioxide.
    Type: Grant
    Filed: March 11, 1975
    Date of Patent: March 1, 1977
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul Edward Aldrich, Gilbert Harvey Berezin, Bruce Ivor Dittmar