Patents by Inventor Paul Edward Kearney

Paul Edward Kearney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230408530
    Abstract: The present invention provides compositions and methods for due date and time to birth prediction for a pregnancy with significantly higher accuracy than current clinical methods. The compositions and methods for due date and time to birth prediction for a pregnancy can also identify those pregnancies that will deliver earlier than the due date derived from LMP and/or US dating.
    Type: Application
    Filed: March 31, 2023
    Publication date: December 21, 2023
    Inventors: John Jay Boniface, Paul Edward Kearney, Julja Burchard, Gregory Charles Critchfield, Durlin Edward Hickok, Tracey Cristine Fleischer, Ashoka Dharmapriya Polpitiya
  • Patent number: 11662351
    Abstract: Compositions and methods for predicting due date and time to birth for a pregnancy with significantly higher accuracy than current clinical methods. The compositions and methods for predicting due date and time to birth for a pregnancy can also identify those pregnancies that will deliver earlier than the due date derived from Last Menstrual Period (LMP) and/or obstetric ultrasonography (US) dating.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: May 30, 2023
    Assignee: Sera Prognostics, Inc.
    Inventors: John Jay Boniface, Paul Edward Kearney, Julja Burchard, Gregory Charles Critchfield, Durlin Edward Hickok, Tracey Cristine Fleischer, Ashoka Dharmapriya Polpitiya
  • Patent number: 11193935
    Abstract: The present invention provides methods for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung condition. The present invention also provides compositions comprising these biomarker proteins and methods of using these biomarker proteins or panels thereof to diagnose, classify, and monitor various lung conditions. The methods and compositions provided herein may be used to diagnose or classify a subject as having lung cancer or a non-cancerous condition, and to distinguish between different types of cancer (e.g., malignant versus benign, SCLC versus NSCLC).
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: December 7, 2021
    Assignee: Biodesix, Inc.
    Inventors: Paul Edward Kearney, Kenneth Charles Fang, Xiao-Jun Li, Clive Hayward
  • Patent number: 10802027
    Abstract: Methods are provided for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung condition. Also provided are compositions comprising these biomarker proteins and methods of using these biomarker proteins or panels thereof to diagnose, classify, and monitor various lung conditions. The methods and compositions provided herein may be used to diagnose or classify a subject as having lung cancer or a non-cancerous condition, and to distinguish between different types of cancer (e.g., malignant versus benign, SCLC versus NSCLC).
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: October 13, 2020
    Assignee: Biodesix, Inc.
    Inventors: Paul Edward Kearney, Kenneth Charles Fang, Xiao-Jun Li, Clive Hayward
  • Patent number: 10534002
    Abstract: Provided herein are methods for developing selected reaction monitoring mass spectrometry (LC-SRM-MS) assays.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: January 14, 2020
    Assignee: Biodesix, Inc.
    Inventors: Paul Edward Kearney, Xiao-Jun Li, Clive Hayward, Miguel Dominguez Geeraerts
  • Publication number: 20190234954
    Abstract: The present invention provides compositions and methods for due date and time to birth prediction for a pregnancy with significantly higher accuracy than current clinical methods. The compositions and methods for due date and time to birth prediction for a pregnancy can also identify those pregnancies that will deliver earlier than the due date derived from LMP and/or US dating.
    Type: Application
    Filed: August 17, 2018
    Publication date: August 1, 2019
    Inventors: John Jay Boniface, Paul Edward Kearney, Julja Burchard, Gregory Charles Critchfield, Durlin Edward Hickok, Tracey Cristine Fleischer, Ashoka Dharmapriya Polpitiya
  • Patent number: 10338074
    Abstract: Methods are provided for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung condition. Also provided are compositions comprising these biomarker proteins and methods of using these biomarker proteins or panels thereof to diagnose, classify, and monitor various lung conditions. The methods and compositions provided herein may be used to diagnose or classify a subject as having lung cancer or a non-cancerous condition, and to distinguish between different types of cancer (e.g., malignant versus benign, SCLC versus NSCLC).
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: July 2, 2019
    Assignee: Biodesix, Inc.
    Inventors: Paul Edward Kearney, Kenneth Charles Fang, Xiao-Jun Li, Clive Hayward
  • Publication number: 20190177367
    Abstract: The present application provides stable peptide-based Akt capture agents and the use thereof as detection, diagnosis, and treatment agents. The application further provides novel methods of developing stable peptide-based capture agents, including Akt capture agents, using iterative on-bead in situ click chemistry.
    Type: Application
    Filed: February 20, 2019
    Publication date: June 13, 2019
    Inventors: James R. Heath, Arundhati Nag, Samir Das, Kaycie M. Deyle, Steven Wesley Millward, Paul Edward Kearney
  • Patent number: 10221214
    Abstract: The present application provides stable peptide-based Akt capture agents and the use thereof as detection, diagnosis, and treatment agents. The application further provides novel methods of developing stable peptide-based capture agents, including Akt capture agents, using iterative on-bead in situ click chemistry.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: March 5, 2019
    Assignee: INDI MOLECULAR, INC.
    Inventors: James R. Heath, Arundhati Nag, Samir Das, Kaycie M. Deyle, Steven Wesley Millward, Paul Edward Kearney
  • Publication number: 20180284128
    Abstract: Provided herein are methods for developing selected reaction monitoring mass spectrometry (LC-SRM-MS) assays.
    Type: Application
    Filed: June 7, 2018
    Publication date: October 4, 2018
    Inventors: Paul Edward Kearney, Xiao-Jun Li, Clive Hayward
  • Publication number: 20180067119
    Abstract: Methods are provided for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung condition. Also provided are compositions comprising these biomarker proteins and methods of using these biomarker proteins or panels thereof to diagnose, classify, and monitor various lung conditions. The methods and compositions provided herein may be used to diagnose or classify a subject as having lung cancer or a non-cancerous condition, and to distinguish between different types of cancer (e.g., malignant versus benign, SCLC versus NSCLC).
    Type: Application
    Filed: October 18, 2017
    Publication date: March 8, 2018
    Inventors: Paul Edward KEARNEY, Kenneth Charles FANG, Xiao-Jun LI, Clive HAYWARD, Douglas SPICER
  • Publication number: 20180059113
    Abstract: Methods are provided for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung condition. Also provided are compositions comprising these biomarker proteins and methods of using these biomarker proteins or panels thereof to diagnose, classify, and monitor various lung conditions. The methods and compositions provided herein may be used to diagnose or classify a subject as having lung cancer or a non-cancerous condition, and to distinguish between different types of cancer (e.g., malignant versus benign, SCLC versus NSCLC).
    Type: Application
    Filed: May 5, 2017
    Publication date: March 1, 2018
    Inventors: Paul Edward KEARNEY, Kenneth Charles Fang, Xiao-Jun Li, Clive Hayward
  • Publication number: 20180011099
    Abstract: The present invention provides methods for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung condition. The present invention also provides compositions comprising these biomarker proteins and methods of using these biomarker proteins or panels thereof to diagnose, classify, and monitor various lung conditions. The methods and compositions provided herein may be used to diagnose or classify a subject as having lung cancer or a non-cancerous condition, and to distinguish between different types of cancer (e.g., malignant versus benign, SCLC versus NSCLC).
    Type: Application
    Filed: August 18, 2017
    Publication date: January 11, 2018
    Inventors: Paul Edward Kearney, Kenneth Charles Fang, Xiao-Jun Li, Clive Hayward
  • Publication number: 20180003724
    Abstract: Novel compositions, methods, assays and kits directed to a diagnostic panel for Alzheimer's disease are provided. In one embodiment, the diagnostic panel includes one or more proteins associated with Alzheimer's disease.
    Type: Application
    Filed: August 24, 2017
    Publication date: January 4, 2018
    Inventors: Xiao-Jun LI, Paul Edward KEARNEY
  • Publication number: 20170299604
    Abstract: Provided herein are methods for developing selected reaction monitoring mass spectrometry (LC-SRM-MS) assays.
    Type: Application
    Filed: November 18, 2016
    Publication date: October 19, 2017
    Inventors: Paul Edward Kearney, Xiao-Jun Li, Clive Hayward
  • Publication number: 20170299605
    Abstract: Provided herein are methods for developing selected reaction monitoring mass spectrometry (LC-SRM-MS) assays.
    Type: Application
    Filed: June 30, 2017
    Publication date: October 19, 2017
    Inventors: Paul Edward Kearney, Xiao-Jun Li, Clive Hayward
  • Publication number: 20170269090
    Abstract: Presented herein are compositions, methods, and kits for determining whether a pulmonary nodule is cancer and/or is not cancer.
    Type: Application
    Filed: March 13, 2017
    Publication date: September 21, 2017
    Inventors: Paul Edward KEARNEY, Xiao-Jun Li, Clive Hayward
  • Publication number: 20170212120
    Abstract: Provided herein are methods for developing selected reaction monitoring mass spectrometry (LC-SRM-MS) assays.
    Type: Application
    Filed: March 31, 2017
    Publication date: July 27, 2017
    Inventors: Paul Edward KEARNEY, Xiao-Jun Li, Clive HAYWARD, Miguel Dominguez GEERAERTS
  • Publication number: 20170184596
    Abstract: The present application provides novel compositions, methods, and assays for use in identification of appropriate diagnostic markers in blood. These compositions, methods, and assays are capable of distinguishing normal levels of detectable markers from changes in marker levels that are indicative of changes in health status.
    Type: Application
    Filed: March 3, 2017
    Publication date: June 29, 2017
    Inventors: Xiao-Jun Li, Paul Edward Kearney
  • Publication number: 20170168058
    Abstract: Methods are provided for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung condition. Also provided are compositions comprising these biomarker proteins and methods of using these biomarker proteins or panels thereof to diagnose, classify, and monitor various lung conditions. The methods and compositions provided herein may be used to diagnose or classify a subject as having lung cancer or a non-cancerous condition, and to distinguish between different types of cancer (e.g., malignant versus benign, SCLC versus NSCLC).
    Type: Application
    Filed: February 8, 2017
    Publication date: June 15, 2017
    Inventors: Paul EDWARD Kearney, Clive Hayward, Xiao-Jun Li