Patents by Inventor Paul F. Hollenberg

Paul F. Hollenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnosis and treatment of osteosarcoma
    Publication number: 20030219802
    Abstract: The present invention relates to compositions and methods for the diagnosis, prognosis, and treatment of cancer. In particular, the present invention provides compositions and methods of using P450 3A4/5 expression in the diagnosis, prognosis, and treatment of osteosarcoma. The present invention thus provides improved compositions and methods for providing prognoses to osteosarcoma patients.
    Type: Application
    Filed: March 7, 2003
    Publication date: November 27, 2003
    Applicant: The Regents of the University of Michigan
    Inventors: Hassan R. Dhaini, Laurence H. Baker, Paul F. Hollenberg, Timothy D. Johnson, Dafydd G. Thomas
  • Compositions containing Bergamottin for increasing the oral bioavailability of pharmaceutical agents
    Patent number: 6509371
    Abstract: Bergamottin, principle compound in grapefruit juice responsible for inhibition of p450 3a4, the predominant p450 enzyme in the intestine, is coadministered with a compound having low bioavailability to a patient to increase oral bioavailability of the compound and pharmaceutical compositions of the same, as well as a method of isolating bg from grapefruit juice.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: January 21, 2003
    Assignee: Warner-Lambert Company
    Inventors: Kan He, Paul F. Hollenberg, Thomas F. Woolf
  • Conjugation of aromatic amines or nitro-containing compounds with proteins or polypeptides by photoirradiation of the azide derivatives with ultraviolet light in order to produce antibodies against the haptens
    Patent number: 4835258
    Abstract: A method of linking primary aromatic amine- or nitro-compounds to carrier proteins by photochemical reactions in order to produce antibodies against the haptens.
    Type: Grant
    Filed: December 24, 1986
    Date of Patent: May 30, 1989
    Assignee: Northwestsern University
    Inventors: Paul F. Hollenberg, Ramendra N. Pandey