Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.

Abstract: A mounting assembly secures a generator and facilitates attachment to a railroad railcar on the end of the railcar axle. The generator produces electricity from the axle of a railroad railcar while it is traveling on a railroad track. A generator is mounted with a generator bracket and a backing plate to an existing bearing adapter on the railcar. A drive hub engages axle bolts on the railcar axle. As the railcar axle turns, the drive hub turns and with the drive hub connected to a generator the generator subsequently rotates to supply electricity to the railcar. Different types of generators can be attached with the mounting assembly to the railcar. The mounting assembly allows generators to be mounted without modification to the existing railcar structure.