Patents by Inventor Paul Ferrell
Paul Ferrell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240210407Abstract: The present invention provides compositions and methods for detecting conditions characterized with pathological fibroblasts (e.g., heart failure (e.g., early stages of heart failure) (e.g., cardiomyopathy)) (e.g., idiopathic pulmonary fibrosis) (e.g., nonalcoholic fatty liver disease with cirrhosis) in a subject through detecting aberrant pro-N-cadherin (PNC) cellular localization and/or PNC circulation in blood (e.g., a blood, plasma, serum, a whole blood, buffy coat). In addition, the present invention provides methods for treating conditions characterized with pathological fibroblasts (e.g., heart failure) (e.g., early stages of heart failure) (e.g., cardiomyopathy) (e.g., idiopathic pulmonary fibrosis) (e.g., nonalcoholic fatty liver disease with cirrhosis) in a subject through inhibiting aberrant PNC cellular localization and/or PNC circulation in blood (e.g., a blood, plasma, serum, a whole blood, buffy coat).Type: ApplicationFiled: December 21, 2023Publication date: June 27, 2024Inventors: Paul Ferrell, Kristianne Oristian, Salvatore Pizzo
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Publication number: 20220227881Abstract: Humanized antibody to a pathologically mislocated form of N-cadherin detects and eliminates cells that express the protein extracellularly. These cells are found in fibrotic conditions within heart, lung, and liver, as well as kidney, skin, and other organs effected by fibrosis. The antibody does not affect cells with normal, subcellular location of the protein.Type: ApplicationFiled: January 24, 2022Publication date: July 21, 2022Applicant: Duke UniversityInventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
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Patent number: 11230606Abstract: Humanized antibody to a pathologically mislocated form of N-cadherin detects and eliminates cells that express the protein extracellularly. These cells are found in fibrotic conditions within heart, lung, and liver, as well as kidney, skin, and other organs effected by fibrosis. The antibody does not affect cells with normal, subcellular location of the protein.Type: GrantFiled: March 9, 2020Date of Patent: January 25, 2022Assignee: Duke UniversityInventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
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Patent number: 11022608Abstract: Compositions, kits and methods for assessing the presence of pathological fibroblasts within a biological sample are provided. In addition, compositions, kits and methods for detecting fibrosis are provided. Also provided are methods for treating fibrosis and conditions characterized with pathological fibroblasts.Type: GrantFiled: September 27, 2019Date of Patent: June 1, 2021Assignee: Duke UniversityInventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
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Publication number: 20200369779Abstract: Humanized antibody to a pathologically mislocated form of N-cadherin detects and eliminates cells that express the protein extracellularly. These cells are found in fibrotic conditions within heart, lung, and liver, as well as kidney, skin, and other organs effected by fibrosis. The antibody does not affect cells with normal, subcellular location of the protein.Type: ApplicationFiled: March 9, 2020Publication date: November 26, 2020Applicant: Duke UniversityInventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
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Publication number: 20200319166Abstract: Compositions, kits and methods for assessing the presence of pathological fibroblasts within a biological sample are provided. In addition, compositions, kits and methods for detecting fibrosis are provided. Also provided are methods for treating fibrosis and conditions characterized with pathological fibroblasts.Type: ApplicationFiled: June 23, 2020Publication date: October 8, 2020Inventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
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Publication number: 20200103397Abstract: Compositions, kits and methods for assessing the presence of pathological fibroblasts within a biological sample are provided. In addition, compositions, kits and methods for detecting fibrosis are provided. Also provided are methods for treating fibrosis and conditions characterized with pathological fibroblasts.Type: ApplicationFiled: September 27, 2019Publication date: April 2, 2020Inventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
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Patent number: 10407168Abstract: Various embodiments include a drone having a landing control device that is configured to rotate wings into an auto-rotation decent configuration causing the drone to enter a nose-down attitude and spin about a long axis of the drone, and to collectively control pivot angles of the wings to enables control of decent rate and lateral motion during an auto-rotation descent. The landing control device may be a landing carousel including a pivotal frame secured to a drone body and configured to rotate about a carousel axis extending laterally relative to a longitudinal axis of the body. The landing carousel may include a first wing motor configured to pivot a first wing about a wing pivot axis extending parallel to the carousel axis, and a second wing motor configured to pivot a second wing about the wing pivot axis independent of the pivot the first wing.Type: GrantFiled: August 7, 2017Date of Patent: September 10, 2019Assignee: QUALCOMM IncorporatedInventors: Donald Bolden Hutson, Charles Wheeler Sweet, III, Paul Ferrell
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Patent number: 10230643Abstract: A packet capture system may copy packets from an interface to a bucket. When the bucket is full of packets, a new bucket for incoming packets may be started, and the full bucket may be indexed. During the indexing, each packet may be sorted in the bucket by flow, and each flow may be indexed. Once indexing is complete, the packets are written to a flow ordered FCAP file and the indexes are written to disk. The flow ordered nature of the FCAP file combined with the indices and their associated search algorithms allow for rapid retrieval of captured flows.Type: GrantFiled: April 27, 2016Date of Patent: March 12, 2019Inventor: Paul Ferrell
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Publication number: 20190039728Abstract: Various embodiments include a drone having a landing control device that is configured to rotate wings into an auto-rotation decent configuration causing the drone to enter a nose-down attitude and spin about a long axis of the drone, and to collectively control pivot angles of the wings to enables control of decent rate and lateral motion during an auto-rotation descent. The landing control device may be a landing carousel including a pivotal frame secured to a drone body and configured to rotate about a carousel axis extending laterally relative to a longitudinal axis of the body. The landing carousel may include a first wing motor configured to pivot a first wing about a wing pivot axis extending parallel to the carousel axis, and a second wing motor configured to pivot a second wing about the wing pivot axis independent of the pivot the first wing.Type: ApplicationFiled: August 7, 2017Publication date: February 7, 2019Inventors: Donald Bolden Hutson, Charles Wheeler Sweet, III, Paul Ferrell
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Publication number: 20180281933Abstract: Methods, devices, and systems of various embodiments are disclosed for operating a propeller assembly for use with a UAV. Various embodiments include a propeller assembly including a pivotal arm, a propeller mounted on the pivotal arm, and pivotal leg coupled to the pivotal arm. The pivotal leg may be folded into the pivotal arm and the pivotal arm may be folded into a body of the UAV. A processor may be coupled to the propeller assembly and configured with processor-executable instructions to perform operations of the propeller assembly.Type: ApplicationFiled: July 17, 2017Publication date: October 4, 2018Inventors: Jonathan Paul Davis, Donald Hutson, Paul Ferrell, Clayton Dumstorff, Travis Van Schoyck, Ross Eric Kessler
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Publication number: 20180186471Abstract: An apparatus for mounting cameras to a drone may include a frame having camera mounts for mounting two 190-degree field-of-view cameras in a back-to-back orientation. Positioning two 190-degree field-of-view cameras in a back-to-back orientation enables obtaining 360-degree field-of-view by stitching images from the two cameras together. The frame may be configured to position the cameras at a 30-40-degree tilt angle (e.g., 35°) with respect to a main axis of the drone to enable the respective images to be stitched together with reduced stitch lines while allowing the lower-facing camera to be used for viewing the ground. In some embodiments, the camera apparatus may be mounted to a drone dampening system.Type: ApplicationFiled: March 20, 2017Publication date: July 5, 2018Inventors: Donald Hutson, Gwendolyn Denise Barriac, Paul Ferrell
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Patent number: 9844718Abstract: A snowboard binding includes a baseplate configured to secure to an upper surface of a snowboard a high back and straps secure to the baseplate. A drive plate is secured to the upper surface of the baseplate and has a stiffness effective to change ride properties of the snowboard. The drive plate may include a laminate structure including one or more composite layers such as fiberglass, carbon fiber, aluminum, or titanium. A carriage may mount the drive plate to the snowboard and may define a recess for receiving the drive plate. Tabs may extend from the lower surface of the carriage and engage corresponding apertures in the baseplate. The tabs may have hooked end portions to secure the carriage to the baseplate.Type: GrantFiled: October 19, 2015Date of Patent: December 19, 2017Assignee: Mervin Manufacturing, Inc.Inventors: Paul Ferrel, Dain Engebretsen, Steven Cobb, Ryan Smith
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Publication number: 20170106269Abstract: A snowboard binding includes a baseplate configured to secure to an upper surface of a snowboard a high back and straps secure to the baseplate. A drive plate is secured to the upper surface of the baseplate and has a stiffness effective to change ride properties of the snowboard. The drive plate may include a laminate structure including one or more composite layers such as fiberglass, carbon fiber, aluminum, or titanium. A carriage may mount the drive plate to the snowboard and may define a recess for receiving the drive plate. Tabs may extend from the lower surface of the carriage and engage corresponding apertures in the baseplate. The tabs may have hooked end portions to secure the carriage to the baseplate.Type: ApplicationFiled: October 19, 2015Publication date: April 20, 2017Inventors: Paul Ferrel, Dain Engebretsen, Steven Cobb, Ryan Smith
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Publication number: 20170063695Abstract: A packet capture system may copy packets from an interface to a bucket. When the bucket is full of packets, a new bucket for incoming packets may be started, and the full bucket may be indexed. During the indexing, each packet may be sorted in the bucket by flow, and each flow may be indexed. Once indexing is complete, the packets are written to a flow ordered FCAP file and the indexes are written to disk. The flow ordered nature of the FCAP file combined with the indices and their associated search algorithms allow for rapid retrieval of captured flows.Type: ApplicationFiled: April 27, 2016Publication date: March 2, 2017Inventor: Paul Ferrell
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Patent number: 8096254Abstract: In one preferred embodiment, the present invention provides a system for launching and recovering one or more unmanned, underwater vehicles. The system includes a surface vessel having a generally low waterline for transporting, launching and recovering the unmanned vehicles. The system provides the ability to transport, launch and recover unmanned vehicles from either the port or starboard sides of the surface vessel, utilizing an A-frame hoist assembly which can be moved laterally in a controlled manner between the port and starboard sides of the surface vessel for lifting the unmanned vehicles, and which can be pivoted in a controlled manner to provide the launch and recovery operations.Type: GrantFiled: March 29, 2010Date of Patent: January 17, 2012Assignee: The United States of American as represented by the Secretary of the NavyInventors: Eric Bauer, Kelly Krueger, Paul Ferrell, James Arthur, Ryan Davis
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Publication number: 20050113253Abstract: A particulate fertilizer containing prodiamine is produced by impregnating the fertilizer with a solution of the prodiamine in N-methyl pyrrolidone.Type: ApplicationFiled: November 20, 2003Publication date: May 26, 2005Inventor: Paul Ferrell
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Patent number: 5750130Abstract: Granular pesticide compositions wherein a pesticide material is applied to a granular substrate using a carrier composition which provides improved adhesion of the pesticide to the substrate and abrasion resistance. The carrier composition may also provide controlled release of the pesticide.Type: GrantFiled: August 9, 1996Date of Patent: May 12, 1998Inventors: Paul Ferrell, Alice P. Hudson