Abstract: An adhesive composition which lacks functional groups containing reactive hydrogen moieties and contains no post-polymerization chemical crosslinker finds use in transdermal drug delivery systems. The invention enables the administration of drugs containing a reactive functional group, which drugs have heretofore not been able to be administered by the transdermal route using conventional acrylic adhesives.

Abstract: Vaginal use compositions comprising pellets prepared from a debranched starch. Pellets may be conveniently prepared via extrusion/spheronization.

Abstract: Vaginal use compositions comprising pellets prepared from a debranched starch. Pellets may be conveniently prepared via extrusion/spheronization.

Abstract: Solution acrylic polymers suitable for dispersing drugs are particularly useful in transdermal drug delivery applications.

Abstract: The invention provides films and film forming compositions that can be applied onto a tissue surface. The film and the film forming composition comprise at least one polycarboxylated polymer and at least one polysaccharide.

Abstract: A system for transdermal delivery of risperidone to an individual. The system has a high risperidone loading with suitable permeation enhancers to effect therapeutic flux rate. Acrylate polymeric reservoir with the high risperidone and permeation enhancers dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.

Abstract: A transdermal galantamine delivery system to an individual. The system has a high galantamine loading with suitable permeation enhancers to effect therapeutic flux rate. Acrylate polymeric reservoir with the high galantamine and permeation enhancers dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties for multiple-day delivery.

Abstract: A system for transdermal delivery of norelgestromin (NGMN) to an individual. The system has a high NGMN loading with suitable permeation enhancers to effect therapeutic flux rate. Polyacrylate drug reservoir with the NGMN and high loading of one or more of permeation enhancers and NGMN dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties. Estrogen can be delivered with the NGMN.

Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.

Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.

Abstract: Solution acrylic polymers suitable for dispersing drugs are particularly useful in transdermal drug delivery applications.

Abstract: Acrylic polymers comprising vinyl acetate monomers, hydroxyl functional monomers and low Tg alkyl acrylate monomers are useful in adhesive compositions that find use in skin contact applications.

Abstract: Acrylic polymers comprising a non-primary hydroxyl functional monomer and low Tg alkyl acrylate monomers are useful in adhesive compositions that find use in skin contact applications.

Abstract: Mucoadhesive tablets have a convex surface, a diameter to cup depth ratio of 4-20 and a cup depth to edge thickness ratio of greater than 0.75 swiftly adheres and conforms to the contacting tissue. The tablets are used to administer actives such as, for example, benzocaine.

Abstract: A method for discovering relationships among elements of a transactional conversation includes tagging a transcribed representation of the conversation to identify elements of the conversation and structuring the tagged conversation according to a specified format to produce a structured, tagged representation of the conversation. A set of structured, tagged conversation representations is then analyzed to discover a relationship between a first conversation element and a second conversation element. Tagging the conversation may include evaluating a portion of the conversation, assigning the portion a message type, and assigning a data value to an attribute defined by the message type. The message type may be defined by a conversation policy, wherein the conversation policy identifies conversation elements including conversation states and message types that transition the conversation among the conversation states.

Abstract: The invention provides a safe drug delivery composition that enhances the absolute bioavailability of active agent (drug).

Abstract: A method and apparatus for creating new representations of a conversational policy or conversation are shown. The conversational policy or a specific conversation can be displayed in a tabular form, which emphasizes order and timing. Representing the policy as a ‘filmstrip’ or series of interactions can make writing the conversational policy more understandable.

Abstract: A method and apparatus for taking a visual or verbal representation of a conversational policy and translating the representation into an XML file. The XML file can then be output in one or more formats, such as code used in a policy, a Word version of the XML file, or a visual representation of the XML file.

Abstract: This patent pertains to the use of debranched starch in the preparation of pharmaceutical pellets by extrusion spheronization. Such excipients are useful in any dry dosage form, including tablets and capsules, for either immediate or sustained release.

Abstract: A composition for glazing joints comprises (a) a siloxane polymer having a molecular weight of from 300,000 to 700,000, (b) a siloxane polymer having a molecular weight of from 10,000 to 100,000 (the ratio of component A to component B being in the range of from 10 to 1, to 3 to 1) and a cross linking agent. The composition is preferably sufficiently cross-linked to have an effective surface tackiness. A glazing strip (10) shaped for receiving two or more sheets may be formed from the composition. An advantage of the composition is that it remains adhesive so that in use, this allows glass sheets to be repositioned and removed when dismantling a partition wall.