Abstract: Systems are provided for an imaging system isolation enclosure for use with a medical imaging system includes a pathogen impermeable enclosure for use with one or more of radiation imaging systems and magnetic resonance imaging systems, the pathogen impermeable enclosure is configured to provide a barrier between the imaging system and at least one of a patient user and an imaging room, and an air filtration system including an inlet to supply a cooling air flow to an interior of the imaging system isolation enclosure and an outlet to output exhaust air from an interior of the imaging system isolation enclosure.

Abstract: An intraoperative specimen imaging system is provided. The intraoperative specimen imaging system includes a mammography imaging system configured to acquire imaging data. The intraoperative specimen imaging system also includes a specimen holding system configured to hold a tissue sample, wherein the specimen holding system is retrofittedly coupled to the mammography imaging system, wherein the intraoperative specimen imaging system is configured to acquire imaging data for generating three-dimensional (3D) images of the tissue sample.

Abstract: Systems are provided for a patient isolation unit for use with a medical imaging system includes an enclosure comprised of a pathogen impermeable material compatible with one or more imaging systems. The enclosure includes a base, a first end wall coupled to a first end of the base, a second end wall coupled to a second end of the base, and a cover coupled to a first side of the base, second side of the base, the first end wall and the second end wall for substantially enclosing a patient therein. In another exemplary embodiment, a patient isolation unit for use with a medical imaging system includes a head enclosure comprised of a pathogen impermeable material and a body enclosure coupled to the head enclosure and comprised of a pathogen impermeable material.

Abstract: An intraoperative specimen imaging system is provided. The intraoperative specimen imaging system includes a mammography imaging system configured to acquire imaging data. The intraoperative specimen imaging system also includes a specimen holding system configured to hold a tissue sample, wherein the specimen holding system is retrofittedly coupled to the mammography imaging system, wherein the intraoperative specimen imaging system is configured to acquire imaging data for generating three-dimensional (3D) images of the tissue sample.

Abstract: The present disclosure relates to the design of phantoms configurable using one or more inserts and to their use in generating images that may be used to compare image quality between different imaging systems. Such phantoms may have a modular design with inserts that may be exchanged one for another within a phantom body.

Abstract: An imaging method includes executing a low-dose preparatory scan to an object by applying tube voltages and tube currents in an x-ray source, and generating a first image of the object corresponding to the low-dose preparatory scan. The method further includes generating image quality estimates and dose estimates view by view at least based on the first image. The method includes optimizing the tube voltages and the tube currents to generate optimal profiles for the tube voltage and the tube current. At least one of the optimal profiles for the tube voltage and the tube current is generated based on the image quality estimates and the dose estimates. The method includes executing an acquisition scan by applying the tube voltages and the tube currents based on the optimal profiles and generating a second image of the object corresponding to the acquisition scan. An imaging system is also provided.

Abstract: Design and use of an administered drug in the form of a nanoparticle or molecule is described. In certain examples, the nanoparticle has a core and a shell surrounding the core. The core may be configured or designed to provide useful X-ray attenuating properties, gamma ray emission properties, magnetic properties, or therapeutic effects. In certain aspects, the nanoparticle or molecule is sized so as to either distribute from or remain in the blood pool, while still being eliminated by the kidneys.

Abstract: Design and use of an administered drug in the form of a nanoparticle or molecule is described. In certain examples, the nanoparticle has a core and a shell surrounding the core. The core may be configured or designed to provide useful X-ray attenuating properties, gamma ray emission properties, magnetic properties, or therapeutic effects. In certain aspects, the nanoparticle or molecule is sized so as to either distribute from or remain in the blood pool, while still being eliminated by the kidneys.

Abstract: An imaging method includes executing a low-dose preparatory scan to an object by applying tube voltages and tube currents in an x-ray source, and generating a first image of the object corresponding to the low-dose preparatory scan. The method further includes generating image quality estimates and dose estimates view by view at least based on the first image. The method includes optimizing the tube voltages and the tube currents to generate optimal profiles for the tube voltage and the tube current. At least one of the optimal profiles for the tube voltage and the tube current is generated based on the image quality estimates and the dose estimates. The method includes executing an acquisition scan by applying the tube voltages and the tube currents based on the optimal profiles and generating a second image of the object corresponding to the acquisition scan. An imaging system is also provided.

Abstract: An energy discrimination radiography system includes at least one radiation source configured to alternately irradiate a component with radiation characterized by at least two energy spectra, where the component has a number of constituents. At least one radiation detector is configured to receive radiation passing through the component and a computer is operationally coupled to the detector. The computer is configured to receive data corresponding to each of the energy spectra for a scan of the component, process the data to generate a multi-energy data set, and decompose the multi-energy data set to generate material characterization images in substantially real time. A method for inspecting the component includes irradiating the component, receiving a data stream of energy discriminated data, processing the energy discriminated data, to generate a multi-energy data set, and decomposing the multi-energy data set, to generate material characterization images in substantially real time.