Abstract: A method includes ingesting, by a clinical trial management platform, data from multiple clinical trial site systems associated with multiple clinical trials, responsive to authentication of user credentials of a user, providing the user with access to the clinical trial management platform, based on the user credentials, identifying a particular clinical trial associated with the user, through the clinical trial management platform, providing the user with access to multiple clinical trial software services based on the authenticated user credentials, based on the ingested data for the particular clinical trial associated with the user, presenting to the user a user-specific task list for user tasks related to the particular clinical trial; and through the clinical trial management platform, establishing a communication link between the user and another user, the communication link enabling direct, real-time messaging via the clinical trial management platform between the user and the other user.

Abstract: Provided are methods relating to the treatment of cancer with a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101 in combination with an inhibitor of the tryptophan metabolism pathway, e.g., an indoleamine-2,3-dioxygenase (IDO) inhibitor or a tryptophan-2, 3-dioxygenase (TDO) inhibitor.

Abstract: A system for displaying a demographic data comprises an input interface, a processor, and an output interface. The input interface is configured to receive a location data of a device and to receive a display type. The processor is configured to determine a user characterization data associated with the device and to determine a probability that the device is associated with a location of interest. The output interface is configured to provide an aggregated characterization data associated with the location of interest for display according to the display type. In some embodiments, the system for determining a demographic data comprises a memory coupled to the processor and configured to provide the processor with instructions. In various embodiments, the device is one of a plurality of devices whose data is received and manipulated in order to determine probabilistic demographic data associated with a location.

Abstract: A system for determining a demographic data comprises an input interface configured to receive a location data of a device or group of devices, a processor configured to determine a user characterization data associated with the device or group of devices and to determine a probability that the device or group of devices is associated with a location of interest, and an output interface configured to provide an aggregated characterization data associated with the location of interest.

Abstract: A method for hydrating yeast comprises several steps. A package comprising a thermochromic ink and an indicator is provided. A liquid is provided. The temperature of the liquid is measured by placing the package in contact with the liquid. The liquid is heated or cooled until the thermochromic ink indicates the liquid is within the predetermined temperature range. The liquid and yeast are combined. The package comprises a pouch, a thermochromic ink, and an indicator. The pouch is formed from one or more films sealed together to create an internal space. The thermochromic ink and indicator are arranged relative to each other to indicate when the liquid is within a predetermined temperature range. The thermochromic ink changes color when the liquid is within the predetermined temperature range.

Abstract: Embodiments of the invention relate to methods for assessing and/or improving contact between an electrophysiology catheter and tissue, and catheters for performing the methods. One embodiment relates to a catheter comprising a braided conductive member coupled to the distal end of a shaft, wherein the braided conductive member comprises a plurality of pressure sensitive wires. Another embodiment relates to a catheter comprising a braided conductive member having a plurality of sectors and coupled to the distal end of a shaft, and a balloon assembly constructed and arranged to selectively apply distal pressure to one or more sectors of the braided conductive member.

Abstract: An aqueous non-flammable release composition for use in food preparation comprising water; de-oiled, powdered lecithin; and less than about 10% oil. The de-oiled, powdered lecithin is water miscible which facilitates the use of less or no oil in a release composition, and allows the use of a non-flammable propellant. The non-flammable release composition may be applied to cooking utensils, such as baking and frying pans, and especially grills and the like, in order to prevent or inhibit food from sticking during cooking and to facilitate cleaning; which may be safely applied while a utensil, pan, or grill is hot; near an open flame or heating element; or while food is being cooked.

Abstract: Embodiments of the invention relate to methods for assessing and/or improving contact between an electrophysiology catheter and tissue, and catheters for performing the methods. One embodiment relates to a catheter comprising a braided conductive member coupled to the distal end of a shaft, wherein the braided conductive member comprises a plurality of pressure sensitive wires. Another embodiment relates to a catheter comprising a braided conductive member having a plurality of sectors and coupled to the distal end of a shaft, and a balloon assembly constructed and arranged to selectively apply distal pressure to one or more sectors of the braided conductive member.

Abstract: By combining lecithin and oil as the principal ingredients, a highly effective, uniform, widely dispersed, pan release spray product is achieved with the lecithin comprising a de-oiled powdered lecithin. The liquid lecithin and/or combinations thereof is blended with the vegetable oil, water and/or alcohol to form a stable emulsion that exhibits superior pan release properties. Furthermore, the lecithin emulsions of the present invention are easily formulated with a variety of blending agents to make flavorful salad dressings, marinades, and pet flavor enhancing products, as a non-aerosol, finger pump based product or as an aerosol product.

Abstract: A method of providing customized medical monitoring to a patient is disclosed. The method can include steps of selecting a medical monitoring device for a patient, where the medical monitoring device is associated with a biological transducer, determining at least one desired monitoring parameter, and customizing locally the medical monitoring device to monitor the desired monitoring parameter collected by the biological transducer. The method may further include steps of providing the medical monitoring device to the patient, and monitoring at least one health parameter of the patient from a remote location. The medical monitoring device can also be customized remotely.

Abstract: Perfused tissue is illuminated and light passing through the tissue or reflected from it is detected to produce an electrical signal. Amplitude pulses corresponding to the subject's heart beat are detected in the electrical signal and the areas of these pulses are calculated to produce blood flow values indicative of the blood volume pumped by the heart. The blood flow values may be used alone or in combination with other measured cardiac parameters to evaluate cardiac function.

Abstract: An aqueous non-flammable release composition for use in food preparation comprising water; de-oiled, powdered lecithin; and less than about 10% oil. The de-oiled, powdered lecithin is water miscible which facilitates the use of less or no oil in a release composition, and allows the use of a non-flammable propellant. The non-flammable release composition may be applied to cooking utensils, such as baking and frying pans, and especially grills and the like, in order to prevent or inhibit food from sticking during cooking and to facilitate cleaning; which may be safely applied while a utensil, pan, or grill is hot; near an open flame or heating element; or while food is being cooked.

Abstract: The present invention is directed to combination therapies for treatment of Human Immunodeficiency Virus (HIV) infection comprising administration of a CCR5 antagonist in combination with other therapeutic agents.

Abstract: A method and apparatus for scanning an indicium local to a user on an advertisement or product. The scanning may be carried out by using a user device, such as a cellular phone or personal digital assistant (PDA), as an input device. The indicium may include an alphanumeric code encoded or embedded therein. The alphanumeric code may be sent over a communication network such as the Internet to a lookup server. The lookup server will correlate the alphanumeric code with a location identifier. The location identifier may be a universal resource locator (URL) indicating a specific webpage containing information and/or interactive tools related to the item bearing the indicium.

Abstract: A method of providing customized medical monitoring to a patient is disclosed. The method can include steps of selecting a medical monitoring device for a patient, where the medical monitoring device is associated with a biological transducer, determining at least one desired monitoring parameter, and customizing locally the medical monitoring device to monitor the desired monitoring parameter collected by the biological transducer. The method may further include steps of providing the medical monitoring device to the patient, and monitoring at least one health parameter of the patient from a remote location. The medical monitoring device can also be customized remotely.

Abstract: A method for dynamic control of medications provided to a patient at a remote location is disclosed. The method can include steps of selecting a customized set of medications for a patient, where the customized set of medications at least partially reflect a medical diagnosis of the patient, and providing the customized set of medications to the patient, where the customized set of medications are inaccessible to the patient without authorization from a medical care provider. Further steps of the method can include authorizing the patient to receive a first medication regimen from the customized set of medications, monitoring remotely at least one health parameter of the patient, and authorizing the first medication regimen to be modified to a second medication regimen based at least partially on the at least one health parameter.

Abstract: A cordless telephone system includes a base station and a handset. The base station includes a telephone line interface, a base station chipset coupled to the telephone line interface, and a first radio transceiver coupled to the base station chipset. The handset includes a microphone, a speaker, a processor coupled to the microphone and the speaker, a wireless network interface coupled to the processor, a handset chipset coupled to the processor, and a second radio transceiver coupled to the wireless network interface and the handset chipset. The second radio transceiver is operable to communicate with the first radio transceiver and a third radio transceiver at a device coupled to a computer network. In a cordless telephone mode, a telephone call is communicated between the handset and the base station. In an IP telephone mode, an IP telephone call is communicated between the handset and the device.

Abstract: By combining lecithin and oil as the principal ingredients, a highly effective, uniform, widely dispersed, pan release spray product is achieved with the lecithin comprising a de-oiled powdered lecithin. The liquid lecithin and/or combinations thereof is blended with the vegetable oil, water and/or alcohol to form a stable emulsion that exhibits superior pan release properties. Furthermore, the lecithin emulsions of the present invention are easily formulated with a variety of blending agents to make flavorful salad dressings, marinades, and pet flavor enhancing products, as a non-aerosol, finger pump based product or as an aerosol product.

Abstract: The invention describes a steerable sheath for percutaneous epicardial access. The invention also describes a novel lead to facilitate left ventricular pacing and efficient defibrillation.

Abstract: The invention provides a rotatable infusion sheath apparatus. An apparatus of the invention includes a hub comprising a hub body with a longitudinal bore, at least one infusion inlet in fluid communication with the bore, and at least one elongate catheter sheath attached to the hub body. Generally, the sheath is rotatable with respect to the hub body and forms a substantially fluid- and gas-impervious seal therewith. Articles of manufacture are provided that include a rotatable infusion sheath apparatus of the invention and a catheter.